AAC75324 (menD, b2264)


Aliases : menD, b2264

Description : 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase; SEPHCHC synthase [Ensembl]. Thiamine pyrophosphate enzyme, Middle domain of thiamine pyrophosphate [Interproscan].


Gene families : OG_02_0001378 (OrthoFinder) Phylogenetic Tree(s): OG0001378_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: AAC75324
Cluster HCCA: Cluster_31

Target Alias Description ECC score Gene Family Method Actions
AAL21210 STM2309, menD 2-oxoglutarate decarboxylase [Ensembl]. Thiamine... 0.12 OrthoFinder

Type GO Term Name Evidence Source
MF GO:0003824 catalytic activity IEA Interproscan
MF GO:0030976 thiamine pyrophosphate binding IEA Interproscan
Type GO Term Name Evidence Source
BP GO:0000041 transition metal ion transport IEP Enrichment
MF GO:0000166 nucleotide binding IEP Enrichment
BP GO:0001514 selenocysteine incorporation IEP Enrichment
MF GO:0003690 double-stranded DNA binding IEP Enrichment
MF GO:0003746 translation elongation factor activity IEP Enrichment
MF GO:0005524 ATP binding IEP Enrichment
BP GO:0006281 DNA repair IEP Enrichment
BP GO:0006298 mismatch repair IEP Enrichment
BP GO:0006414 translational elongation IEP Enrichment
BP GO:0006417 regulation of translation IEP Enrichment
BP GO:0006451 translational readthrough IEP Enrichment
BP GO:0006826 iron ion transport IEP Enrichment
BP GO:0006950 response to stress IEP Enrichment
BP GO:0006974 cellular response to DNA damage stimulus IEP Enrichment
MF GO:0008897 holo-[acyl-carrier-protein] synthase activity IEP Enrichment
BP GO:0010608 posttranscriptional regulation of gene expression IEP Enrichment
MF GO:0015232 heme transmembrane transporter activity IEP Enrichment
BP GO:0015886 heme transport IEP Enrichment
MF GO:0016887 ATPase IEP Enrichment
MF GO:0017076 purine nucleotide binding IEP Enrichment
MF GO:0030554 adenyl nucleotide binding IEP Enrichment
MF GO:0030983 mismatched DNA binding IEP Enrichment
BP GO:0032268 regulation of cellular protein metabolic process IEP Enrichment
BP GO:0032324 molybdopterin cofactor biosynthetic process IEP Enrichment
MF GO:0032553 ribonucleotide binding IEP Enrichment
MF GO:0032555 purine ribonucleotide binding IEP Enrichment
MF GO:0032559 adenyl ribonucleotide binding IEP Enrichment
BP GO:0033554 cellular response to stress IEP Enrichment
BP GO:0034248 regulation of cellular amide metabolic process IEP Enrichment
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Enrichment
BP GO:0043545 molybdopterin cofactor metabolic process IEP Enrichment
BP GO:0050896 response to stimulus IEP Enrichment
BP GO:0051189 prosthetic group metabolic process IEP Enrichment
BP GO:0051246 regulation of protein metabolic process IEP Enrichment
BP GO:0051716 cellular response to stimulus IEP Enrichment
MF GO:0097367 carbohydrate derivative binding IEP Enrichment
MF GO:1901265 nucleoside phosphate binding IEP Enrichment
BP GO:1901678 iron coordination entity transport IEP Enrichment
InterPro domains Description Start Stop
IPR032264 MenD_middle 184 388
IPR012001 Thiamin_PyroP_enz_TPP-bd_dom 9 141
IPR011766 TPP_enzyme-bd_C 415 535
UniProtKB P17109