AAC76922 (metL, b3940)

Aliases : metL, b3940

Description : Bifunctional aspartokinase/homoserine dehydrogenase 2 [Ensembl]. Homoserine dehydrogenase, Amino acid kinase family [Interproscan].

Gene families : OG_02_0000145 (OrthoFinder) Phylogenetic Tree(s): OG0000145_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AAC76922
Cluster	HCCA: Cluster_11

Target	Alias	Description	ECC score	Gene Family Method
AAL18966	STM0002, thrA	aspartokinase I [Ensembl]. ACT domain, Homoserine...	0.18	OrthoFinder
AAL22941	STM4101, metL	aspartokinase II [Ensembl]. Homoserine dehydrogenase,...	0.25	OrthoFinder
AAL23044	STM4220, lysC	lysine sensitive aspartokinase III [Ensembl]. ACT...	0.05	OrthoFinder
AGT26473	N559_4889	aspartate kinase III [Ensembl]. Amino acid kinase family...	0.12	OrthoFinder
AKI50307	L2625_02494	aspartate kinase [Ensembl]. CASTOR,...	0.03	OrthoFinder
CPC31970	lysC, ERS093114_00024	Aspartokinase [Ensembl]. Amino acid kinase family [Interproscan].	0.03	OrthoFinder
CPC33474	lysC2, ERS093114_00089	aspartate kinase [Ensembl]. Amino acid kinase family...	0.03	OrthoFinder
KNA50221	VCV51_030256	aspartate kinase [Ensembl]. Amino acid kinase family...	0.16	OrthoFinder
KNA54894	VCV51_031799	homoserine dehydrogenase [Ensembl]. Amino acid kinase...	0.18	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005488	binding	None	Extended
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006520	cellular amino acid metabolic process	IEA	Interproscan
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016491	oxidoreductase activity	IEA	Interproscan
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
MF	GO:0050661	NADP binding	IEA	Interproscan
BP	GO:0055114	obsolete oxidation-reduction process	IEA	Interproscan
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000096	sulfur amino acid metabolic process	IEP	Enrichment
BP	GO:0000097	sulfur amino acid biosynthetic process	IEP	Enrichment
MF	GO:0003871	5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity	IEP	Enrichment
MF	GO:0004478	methionine adenosyltransferase activity	IEP	Enrichment
MF	GO:0004489	methylenetetrahydrofolate reductase (NAD(P)H) activity	IEP	Enrichment
MF	GO:0004665	prephenate dehydrogenase (NADP+) activity	IEP	Enrichment
BP	GO:0006534	cysteine metabolic process	IEP	Enrichment
BP	GO:0006555	methionine metabolic process	IEP	Enrichment
BP	GO:0006556	S-adenosylmethionine biosynthetic process	IEP	Enrichment
BP	GO:0006570	tyrosine metabolic process	IEP	Enrichment
BP	GO:0006571	tyrosine biosynthetic process	IEP	Enrichment
BP	GO:0006790	sulfur compound metabolic process	IEP	Enrichment
MF	GO:0008172	S-methyltransferase activity	IEP	Enrichment
MF	GO:0008977	prephenate dehydrogenase (NAD+) activity	IEP	Enrichment
BP	GO:0009066	aspartate family amino acid metabolic process	IEP	Enrichment
BP	GO:0009067	aspartate family amino acid biosynthetic process	IEP	Enrichment
BP	GO:0009069	serine family amino acid metabolic process	IEP	Enrichment
BP	GO:0009072	aromatic amino acid family metabolic process	IEP	Enrichment
BP	GO:0009073	aromatic amino acid family biosynthetic process	IEP	Enrichment
BP	GO:0009086	methionine biosynthetic process	IEP	Enrichment
BP	GO:0009092	homoserine metabolic process	IEP	Enrichment
BP	GO:0009095	aromatic amino acid family biosynthetic process, prephenate pathway	IEP	Enrichment
BP	GO:0016053	organic acid biosynthetic process	IEP	Enrichment
MF	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	IEP	Enrichment
MF	GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	IEP	Enrichment
MF	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	IEP	Enrichment
MF	GO:0016887	ATPase	IEP	Enrichment
BP	GO:0019346	transsulfuration	IEP	Enrichment
MF	GO:0019842	vitamin binding	IEP	Enrichment
MF	GO:0030170	pyridoxal phosphate binding	IEP	Enrichment
MF	GO:0032553	ribonucleotide binding	IEP	Enrichment
MF	GO:0042085	5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity	IEP	Enrichment
MF	GO:0043167	ion binding	IEP	Enrichment
MF	GO:0043168	anion binding	IEP	Enrichment
BP	GO:0043648	dicarboxylic acid metabolic process	IEP	Enrichment
BP	GO:0044272	sulfur compound biosynthetic process	IEP	Enrichment
BP	GO:0046417	chorismate metabolic process	IEP	Enrichment
BP	GO:0046500	S-adenosylmethionine metabolic process	IEP	Enrichment
BP	GO:0050667	homocysteine metabolic process	IEP	Enrichment
MF	GO:0070279	vitamin B6 binding	IEP	Enrichment
MF	GO:0097367	carbohydrate derivative binding	IEP	Enrichment
BP	GO:1901605	alpha-amino acid metabolic process	IEP	Enrichment
BP	GO:1901607	alpha-amino acid biosynthetic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR001342	HDH_cat	608	803
IPR001048	Asp/Glu/Uridylate_kinase	12	284
IPR005106	Asp/hSer_DH_NAD-bd	465	600

External Links

UniProtKB	P00562

AAC76922 (metL, b3940)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation