EDJ91669 (purH, CGSHi22421_07938)

Aliases : purH, CGSHi22421_07938

Description : bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Ensembl]. MGS-like domain, AICARFT/IMPCHase bienzyme [Interproscan].

Gene families : OG_02_0000542 (OrthoFinder) Phylogenetic Tree(s): OG0000542_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: EDJ91669
Cluster	HCCA: Cluster_5

Target	Alias	Description	ECC score	Gene Family Method
AAC76980	purH, b4006	IMP cyclohydrolase and...	0.1	OrthoFinder
AAK98855	spr0051, purH	Phosphoribosylaminoimidazolecarboxamide...	0.05	OrthoFinder
AAL23004	STM4176, purH	phosphoribosylaminoimidazolecarboxamide...	0.08	OrthoFinder
AEA94177	purH, OG1RF_11490	bifunctional purine biosynthesis protein PurH [Ensembl]....	0.04	OrthoFinder
AGT26493	N559_4909	phosphoribosylaminoimidazolecarboxamide...	0.07	OrthoFinder
AKI49759	purH, L2625_01901	phosphoribosylaminoimidazolecarboxamide...	0.05	OrthoFinder
CCG26113	No alias	IMP cyclohydrolase /...	0.06	OrthoFinder
CCL18088	purH, BN171_210024	Bifunctional purine biosynthesis protein purH (Includes:...	0.04	OrthoFinder
CPC40781	purH, ERS093114_00351	IMP cyclohydrolase [Ensembl]. MGS-like domain,...	0.08	OrthoFinder
CRO51482	purH	Bifunctional purine biosynthesis protein PurH [Ensembl]....	0.03	OrthoFinder
KNA49649	VCV51_030205	phosphoribosylaminoimidazolecarboxamide...	0.06	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003937	IMP cyclohydrolase activity	IEA	Interproscan
MF	GO:0004643	phosphoribosylaminoimidazolecarboxamide formyltransferase activity	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006163	purine nucleotide metabolic process	None	Extended
BP	GO:0006164	purine nucleotide biosynthetic process	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006753	nucleoside phosphate metabolic process	None	Extended
BP	GO:0006793	phosphorus metabolic process	None	Extended
BP	GO:0006796	phosphate-containing compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009117	nucleotide metabolic process	None	Extended
BP	GO:0009165	nucleotide biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016741	transferase activity, transferring one-carbon groups	None	Extended
MF	GO:0016742	hydroxymethyl-, formyl- and related transferase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	None	Extended
MF	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	None	Extended
BP	GO:0018130	heterocycle biosynthetic process	None	Extended
MF	GO:0019238	cyclohydrolase activity	None	Extended
BP	GO:0019438	aromatic compound biosynthetic process	None	Extended
BP	GO:0019637	organophosphate metabolic process	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034654	nucleobase-containing compound biosynthetic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044271	cellular nitrogen compound biosynthetic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0055086	nucleobase-containing small molecule metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0072521	purine-containing compound metabolic process	None	Extended
BP	GO:0072522	purine-containing compound biosynthetic process	None	Extended
BP	GO:0090407	organophosphate biosynthetic process	None	Extended
BP	GO:1901293	nucleoside phosphate biosynthetic process	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901362	organic cyclic compound biosynthetic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003684	damaged DNA binding	IEP	Enrichment
MF	GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	IEP	Enrichment
MF	GO:0004018	N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity	IEP	Enrichment
MF	GO:0004470	malic enzyme activity	IEP	Enrichment
MF	GO:0004471	malate dehydrogenase (decarboxylating) (NAD+) activity	IEP	Enrichment
MF	GO:0004486	methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity	IEP	Enrichment
MF	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity	IEP	Enrichment
MF	GO:0004637	phosphoribosylamine-glycine ligase activity	IEP	Enrichment
MF	GO:0004645	1,4-alpha-oligoglucan phosphorylase activity	IEP	Enrichment
MF	GO:0005215	transporter activity	IEP	Enrichment
BP	GO:0005975	carbohydrate metabolic process	IEP	Enrichment
BP	GO:0005996	monosaccharide metabolic process	IEP	Enrichment
BP	GO:0006004	fucose metabolic process	IEP	Enrichment
BP	GO:0006071	glycerol metabolic process	IEP	Enrichment
BP	GO:0006144	purine nucleobase metabolic process	IEP	Enrichment
BP	GO:0006188	IMP biosynthetic process	IEP	Enrichment
BP	GO:0006189	'de novo' IMP biosynthetic process	IEP	Enrichment
BP	GO:0006289	nucleotide-excision repair	IEP	Enrichment
BP	GO:0006777	Mo-molybdopterin cofactor biosynthetic process	IEP	Enrichment
BP	GO:0006810	transport	IEP	Enrichment
MF	GO:0008028	monocarboxylic acid transmembrane transporter activity	IEP	Enrichment
MF	GO:0008184	glycogen phosphorylase activity	IEP	Enrichment
MF	GO:0008736	L-fucose isomerase activity	IEP	Enrichment
MF	GO:0008927	mannonate dehydratase activity	IEP	Enrichment
BP	GO:0009113	purine nucleobase biosynthetic process	IEP	Enrichment
BP	GO:0009123	nucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009124	nucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009126	purine nucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009127	purine nucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009156	ribonucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009161	ribonucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009167	purine ribonucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009168	purine ribonucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009403	toxin biosynthetic process	IEP	Enrichment
BP	GO:0009404	toxin metabolic process	IEP	Enrichment
MF	GO:0015129	lactate transmembrane transporter activity	IEP	Enrichment
MF	GO:0015267	channel activity	IEP	Enrichment
BP	GO:0015718	monocarboxylic acid transport	IEP	Enrichment
BP	GO:0015727	lactate transport	IEP	Enrichment
BP	GO:0015850	organic hydroxy compound transport	IEP	Enrichment
CC	GO:0016020	membrane	IEP	Enrichment
MF	GO:0016615	malate dehydrogenase activity	IEP	Enrichment
MF	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	IEP	Enrichment
MF	GO:0016829	lyase activity	IEP	Enrichment
MF	GO:0016842	amidine-lyase activity	IEP	Enrichment
CC	GO:0019008	molybdopterin synthase complex	IEP	Enrichment
MF	GO:0019203	carbohydrate phosphatase activity	IEP	Enrichment
BP	GO:0019318	hexose metabolic process	IEP	Enrichment
BP	GO:0019400	alditol metabolic process	IEP	Enrichment
BP	GO:0019720	Mo-molybdopterin cofactor metabolic process	IEP	Enrichment
BP	GO:0019748	secondary metabolic process	IEP	Enrichment
MF	GO:0022803	passive transmembrane transporter activity	IEP	Enrichment
MF	GO:0022857	transmembrane transporter activity	IEP	Enrichment
MF	GO:0030151	molybdenum ion binding	IEP	Enrichment
MF	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity	IEP	Enrichment
BP	GO:0043545	molybdopterin cofactor metabolic process	IEP	Enrichment
BP	GO:0044550	secondary metabolite biosynthetic process	IEP	Enrichment
BP	GO:0046040	IMP metabolic process	IEP	Enrichment
MF	GO:0046914	transition metal ion binding	IEP	Enrichment
MF	GO:0050308	sugar-phosphatase activity	IEP	Enrichment
BP	GO:0051179	localization	IEP	Enrichment
BP	GO:0051189	prosthetic group metabolic process	IEP	Enrichment
BP	GO:0051234	establishment of localization	IEP	Enrichment
MF	GO:0051499	D-aminoacyl-tRNA deacylase activity	IEP	Enrichment
BP	GO:0055085	transmembrane transport	IEP	Enrichment
MF	GO:1901618	organic hydroxy compound transmembrane transporter activity	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR011607	MGS-like_dom	18	131
IPR002695	PurH-like	136	463

External Links

No external refs found!

EDJ91669 (purH, CGSHi22421_07938)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation