AGT25961 (N559_4351)


Aliases : N559_4351

Description : 2-isopropylmalate synthase [Ensembl]. LeuA allosteric (dimerisation) domain [InterProScan].


Gene families : OG_02_0000655 (OrthoFinder) Phylogenetic Tree(s): OG0000655_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: AGT25961
Cluster HCCA: Cluster_11

Target Alias Description ECC score Gene Family Method Actions
AAC73185 leuA, b0074 2-isopropylmalate synthase [Ensembl]. HMGL-like, LeuA... 0.05 OrthoFinder
AAK99939 spr1136 2-isopropylmalate synthase, truncation [Ensembl]. LeuA... 0.03 OrthoFinder
AAL19077 STM0113, leuA 2-isopropylmalate synthase [Ensembl]. HMGL-like, LeuA... 0.27 OrthoFinder
AHY40904 CJ8421_08660 2-isopropylmalate synthase [Ensembl]. HMGL-like, LeuA... 0.02 OrthoFinder
AKI49982 leuA, L2625_02135 2-isopropylmalate synthase [Ensembl]. Pyruvate... 0.13 OrthoFinder
CCL17001 aksA, BN171_1070003 Trans-homoaconitate synthase [Ensembl]. HMGL-like [Interproscan]. 0.04 OrthoFinder
CPD08084 leuA_2, ERS093114_02010 2-isopropylmalate synthase [Ensembl]. HMGL-like, LeuA... 0.1 OrthoFinder
KNA51159 VCV51_031676 2-isopropylmalate synthase [Ensembl]. HMGL-like, LeuA... 0.14 OrthoFinder

Type GO Term Name Evidence Source
MF GO:0003824 catalytic activity IEA Interproscan
MF GO:0003852 2-isopropylmalate synthase activity IEA Interproscan
BP GO:0009098 leucine biosynthetic process IEA Interproscan
Type GO Term Name Evidence Source
BP GO:0000096 sulfur amino acid metabolic process IEP Enrichment
BP GO:0000105 histidine biosynthetic process IEP Enrichment
MF GO:0000166 nucleotide binding IEP Enrichment
MF GO:0000287 magnesium ion binding IEP Enrichment
MF GO:0003871 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity IEP Enrichment
MF GO:0003879 ATP phosphoribosyltransferase activity IEP Enrichment
MF GO:0004399 histidinol dehydrogenase activity IEP Enrichment
MF GO:0004424 imidazoleglycerol-phosphate dehydratase activity IEP Enrichment
MF GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity IEP Enrichment
MF GO:0004635 phosphoribosyl-AMP cyclohydrolase activity IEP Enrichment
MF GO:0005488 binding IEP Enrichment
BP GO:0006534 cysteine metabolic process IEP Enrichment
BP GO:0006536 glutamate metabolic process IEP Enrichment
BP GO:0006537 glutamate biosynthetic process IEP Enrichment
BP GO:0006547 histidine metabolic process IEP Enrichment
BP GO:0006555 methionine metabolic process IEP Enrichment
BP GO:0006790 sulfur compound metabolic process IEP Enrichment
BP GO:0006810 transport IEP Enrichment
MF GO:0008964 phosphoenolpyruvate carboxylase activity IEP Enrichment
BP GO:0009066 aspartate family amino acid metabolic process IEP Enrichment
BP GO:0009069 serine family amino acid metabolic process IEP Enrichment
BP GO:0009086 methionine biosynthetic process IEP Enrichment
BP GO:0009092 homoserine metabolic process IEP Enrichment
MF GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity IEP Enrichment
MF GO:0015930 glutamate synthase activity IEP Enrichment
BP GO:0015977 carbon fixation IEP Enrichment
CC GO:0016020 membrane IEP Enrichment
MF GO:0016491 oxidoreductase activity IEP Enrichment
MF GO:0016614 oxidoreductase activity, acting on CH-OH group of donors IEP Enrichment
MF GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEP Enrichment
MF GO:0016743 carboxyl- or carbamoyltransferase activity IEP Enrichment
MF GO:0016887 ATPase IEP Enrichment
MF GO:0017076 purine nucleotide binding IEP Enrichment
MF GO:0019238 cyclohydrolase activity IEP Enrichment
BP GO:0019346 transsulfuration IEP Enrichment
MF GO:0019842 vitamin binding IEP Enrichment
MF GO:0030170 pyridoxal phosphate binding IEP Enrichment
MF GO:0030976 thiamine pyrophosphate binding IEP Enrichment
MF GO:0032555 purine ribonucleotide binding IEP Enrichment
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Enrichment
MF GO:0036094 small molecule binding IEP Enrichment
MF GO:0042085 5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity IEP Enrichment
MF GO:0043167 ion binding IEP Enrichment
MF GO:0043168 anion binding IEP Enrichment
BP GO:0043650 dicarboxylic acid biosynthetic process IEP Enrichment
BP GO:0050667 homocysteine metabolic process IEP Enrichment
BP GO:0051179 localization IEP Enrichment
BP GO:0051234 establishment of localization IEP Enrichment
MF GO:0051287 NAD binding IEP Enrichment
BP GO:0055085 transmembrane transport IEP Enrichment
BP GO:0055114 obsolete oxidation-reduction process IEP Enrichment
MF GO:0070279 vitamin B6 binding IEP Enrichment
MF GO:0097159 organic cyclic compound binding IEP Enrichment
MF GO:1901265 nucleoside phosphate binding IEP Enrichment
MF GO:1901363 heterocyclic compound binding IEP Enrichment
BP GO:1901605 alpha-amino acid metabolic process IEP Enrichment
BP GO:1901607 alpha-amino acid biosynthetic process IEP Enrichment
MF GO:1901681 sulfur compound binding IEP Enrichment
InterPro domains Description Start Stop
IPR013709 2-isopropylmalate_synth_dimer 369 499
IPR000891 PYR_CT 4 273
No external refs found!