AKI48775 (L2625_00846)

Aliases : L2625_00846

Description : 3-hydroxy-3-methylglutaryl-CoA reductase [Ensembl]. Hydroxymethylglutaryl-CoA reductase [Interproscan].

Gene families : OG_02_0003081 (OrthoFinder) Phylogenetic Tree(s): OG0003081_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AKI48775
Cluster	HCCA: Cluster_20

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004420	hydroxymethylglutaryl-CoA reductase (NADPH) activity	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006163	purine nucleotide metabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006753	nucleoside phosphate metabolic process	None	Extended
BP	GO:0006793	phosphorus metabolic process	None	Extended
BP	GO:0006796	phosphate-containing compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009117	nucleotide metabolic process	None	Extended
BP	GO:0009150	purine ribonucleotide metabolic process	None	Extended
BP	GO:0009259	ribonucleotide metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0015936	coenzyme A metabolic process	IEA	Interproscan
MF	GO:0016491	oxidoreductase activity	None	Extended
MF	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	None	Extended
MF	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	None	Extended
BP	GO:0019637	organophosphate metabolic process	None	Extended
BP	GO:0019693	ribose phosphate metabolic process	None	Extended
BP	GO:0033865	nucleoside bisphosphate metabolic process	None	Extended
BP	GO:0033875	ribonucleoside bisphosphate metabolic process	None	Extended
BP	GO:0034032	purine nucleoside bisphosphate metabolic process	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0055086	nucleobase-containing small molecule metabolic process	None	Extended
BP	GO:0055114	obsolete oxidation-reduction process	IEA	Interproscan
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0072521	purine-containing compound metabolic process	None	Extended
BP	GO:1901135	carbohydrate derivative metabolic process	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEP	Enrichment
MF	GO:0000287	magnesium ion binding	IEP	Enrichment
MF	GO:0003678	DNA helicase activity	IEP	Enrichment
MF	GO:0003690	double-stranded DNA binding	IEP	Enrichment
MF	GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	IEP	Enrichment
MF	GO:0004150	dihydroneopterin aldolase activity	IEP	Enrichment
MF	GO:0004386	helicase activity	IEP	Enrichment
MF	GO:0004478	methionine adenosyltransferase activity	IEP	Enrichment
MF	GO:0004486	methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity	IEP	Enrichment
MF	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity	IEP	Enrichment
MF	GO:0004817	cysteine-tRNA ligase activity	IEP	Enrichment
MF	GO:0005436	sodium:phosphate symporter activity	IEP	Enrichment
MF	GO:0005488	binding	IEP	Enrichment
MF	GO:0005524	ATP binding	IEP	Enrichment
BP	GO:0006259	DNA metabolic process	IEP	Enrichment
BP	GO:0006281	DNA repair	IEP	Enrichment
BP	GO:0006289	nucleotide-excision repair	IEP	Enrichment
BP	GO:0006298	mismatch repair	IEP	Enrichment
BP	GO:0006423	cysteinyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006556	S-adenosylmethionine biosynthetic process	IEP	Enrichment
BP	GO:0006629	lipid metabolic process	IEP	Enrichment
BP	GO:0006720	isoprenoid metabolic process	IEP	Enrichment
BP	GO:0006950	response to stress	IEP	Enrichment
BP	GO:0006974	cellular response to DNA damage stimulus	IEP	Enrichment
MF	GO:0008094	ATPase, acting on DNA	IEP	Enrichment
BP	GO:0008299	isoprenoid biosynthetic process	IEP	Enrichment
MF	GO:0008661	1-deoxy-D-xylulose-5-phosphate synthase activity	IEP	Enrichment
MF	GO:0008897	holo-[acyl-carrier-protein] synthase activity	IEP	Enrichment
MF	GO:0015081	sodium ion transmembrane transporter activity	IEP	Enrichment
MF	GO:0015293	symporter activity	IEP	Enrichment
MF	GO:0015294	solute:cation symporter activity	IEP	Enrichment
MF	GO:0015370	solute:sodium symporter activity	IEP	Enrichment
MF	GO:0016744	transketolase or transaldolase activity	IEP	Enrichment
MF	GO:0016758	hexosyltransferase activity	IEP	Enrichment
MF	GO:0016787	hydrolase activity	IEP	Enrichment
MF	GO:0016887	ATPase	IEP	Enrichment
MF	GO:0017076	purine nucleotide binding	IEP	Enrichment
BP	GO:0030258	lipid modification	IEP	Enrichment
BP	GO:0030259	lipid glycosylation	IEP	Enrichment
MF	GO:0030554	adenyl nucleotide binding	IEP	Enrichment
MF	GO:0030983	mismatched DNA binding	IEP	Enrichment
MF	GO:0032553	ribonucleotide binding	IEP	Enrichment
MF	GO:0032555	purine ribonucleotide binding	IEP	Enrichment
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Enrichment
BP	GO:0033554	cellular response to stress	IEP	Enrichment
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Enrichment
MF	GO:0036094	small molecule binding	IEP	Enrichment
MF	GO:0043138	3'-5' DNA helicase activity	IEP	Enrichment
MF	GO:0043167	ion binding	IEP	Enrichment
MF	GO:0043168	anion binding	IEP	Enrichment
MF	GO:0043169	cation binding	IEP	Enrichment
BP	GO:0043170	macromolecule metabolic process	IEP	Enrichment
BP	GO:0044255	cellular lipid metabolic process	IEP	Enrichment
BP	GO:0044341	sodium-dependent phosphate transport	IEP	Enrichment
BP	GO:0046500	S-adenosylmethionine metabolic process	IEP	Enrichment
BP	GO:0050896	response to stimulus	IEP	Enrichment
BP	GO:0051716	cellular response to stimulus	IEP	Enrichment
BP	GO:0070085	glycosylation	IEP	Enrichment
BP	GO:0090304	nucleic acid metabolic process	IEP	Enrichment
MF	GO:0097159	organic cyclic compound binding	IEP	Enrichment
MF	GO:0097367	carbohydrate derivative binding	IEP	Enrichment
MF	GO:0140097	catalytic activity, acting on DNA	IEP	Enrichment
MF	GO:1901265	nucleoside phosphate binding	IEP	Enrichment
MF	GO:1901363	heterocyclic compound binding	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR002202	HMG_CoA_Rdtase	12	383

External Links

No external refs found!

AKI48775 (L2625_00846)

Expression Profile

Co-expression Networks

Functional Annotation