AKI49561 (mutM, L2625_01670)

Aliases : mutM, L2625_01670

Description : formamidopyrimidine-DNA glycosylase [Ensembl]. DNA glycosylase/AP lyase, Formamidopyrimidine-DNA glycosylase, Zinc finger [Interproscan].

Gene families : OG_02_0000689 (OrthoFinder) Phylogenetic Tree(s): OG0000689_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AKI49561
Cluster	HCCA: Cluster_20

Target	Alias	Description	ECC score	Gene Family Method	Actions
AEA93294	mutM, OG1RF_10607	DNA-formamidopyrimidine glycosylase [Ensembl]. Zinc...	0.06	OrthoFinder
CPC86246	mutM, ERS093114_01512	Formamidopyrimidine-DNA glycosylase [Ensembl]. Zinc...	0.03	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	None	Extended
MF	GO:0003684	damaged DNA binding	IEA	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	None	Extended
BP	GO:0006284	base-excision repair	IEA	Interproscan
BP	GO:0006289	nucleotide-excision repair	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008270	zinc ion binding	IEA	Interproscan
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016798	hydrolase activity, acting on glycosyl bonds	None	Extended
MF	GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	IEA	Interproscan
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043169	cation binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
MF	GO:0046872	metal ion binding	None	Extended
MF	GO:0046914	transition metal ion binding	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000160	phosphorelay signal transduction system	IEP	Enrichment
MF	GO:0000166	nucleotide binding	IEP	Enrichment
MF	GO:0003690	double-stranded DNA binding	IEP	Enrichment
MF	GO:0003848	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity	IEP	Enrichment
MF	GO:0003951	NAD+ kinase activity	IEP	Enrichment
MF	GO:0004140	dephospho-CoA kinase activity	IEP	Enrichment
MF	GO:0004150	dihydroneopterin aldolase activity	IEP	Enrichment
MF	GO:0004329	formate-tetrahydrofolate ligase activity	IEP	Enrichment
MF	GO:0004357	glutamate-cysteine ligase activity	IEP	Enrichment
MF	GO:0004420	hydroxymethylglutaryl-CoA reductase (NADPH) activity	IEP	Enrichment
MF	GO:0004672	protein kinase activity	IEP	Enrichment
MF	GO:0005524	ATP binding	IEP	Enrichment
BP	GO:0005996	monosaccharide metabolic process	IEP	Enrichment
BP	GO:0006163	purine nucleotide metabolic process	IEP	Enrichment
BP	GO:0006298	mismatch repair	IEP	Enrichment
BP	GO:0006464	cellular protein modification process	IEP	Enrichment
BP	GO:0006468	protein phosphorylation	IEP	Enrichment
BP	GO:0006553	lysine metabolic process	IEP	Enrichment
BP	GO:0006575	cellular modified amino acid metabolic process	IEP	Enrichment
BP	GO:0006741	NADP biosynthetic process	IEP	Enrichment
BP	GO:0006749	glutathione metabolic process	IEP	Enrichment
BP	GO:0006750	glutathione biosynthetic process	IEP	Enrichment
BP	GO:0006753	nucleoside phosphate metabolic process	IEP	Enrichment
BP	GO:0006760	folic acid-containing compound metabolic process	IEP	Enrichment
BP	GO:0006793	phosphorus metabolic process	IEP	Enrichment
BP	GO:0006796	phosphate-containing compound metabolic process	IEP	Enrichment
BP	GO:0007165	signal transduction	IEP	Enrichment
MF	GO:0008839	4-hydroxy-tetrahydrodipicolinate reductase	IEP	Enrichment
BP	GO:0009085	lysine biosynthetic process	IEP	Enrichment
BP	GO:0009089	lysine biosynthetic process via diaminopimelate	IEP	Enrichment
BP	GO:0009117	nucleotide metabolic process	IEP	Enrichment
BP	GO:0009150	purine ribonucleotide metabolic process	IEP	Enrichment
BP	GO:0009166	nucleotide catabolic process	IEP	Enrichment
BP	GO:0009259	ribonucleotide metabolic process	IEP	Enrichment
BP	GO:0009396	folic acid-containing compound biosynthetic process	IEP	Enrichment
BP	GO:0015936	coenzyme A metabolic process	IEP	Enrichment
BP	GO:0015937	coenzyme A biosynthetic process	IEP	Enrichment
MF	GO:0016301	kinase activity	IEP	Enrichment
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	IEP	Enrichment
MF	GO:0016791	phosphatase activity	IEP	Enrichment
MF	GO:0016853	isomerase activity	IEP	Enrichment
MF	GO:0016879	ligase activity, forming carbon-nitrogen bonds	IEP	Enrichment
BP	GO:0017038	protein import	IEP	Enrichment
MF	GO:0017076	purine nucleotide binding	IEP	Enrichment
BP	GO:0019184	nonribosomal peptide biosynthetic process	IEP	Enrichment
MF	GO:0019203	carbohydrate phosphatase activity	IEP	Enrichment
BP	GO:0019318	hexose metabolic process	IEP	Enrichment
BP	GO:0019637	organophosphate metabolic process	IEP	Enrichment
BP	GO:0019693	ribose phosphate metabolic process	IEP	Enrichment
MF	GO:0030554	adenyl nucleotide binding	IEP	Enrichment
MF	GO:0030983	mismatched DNA binding	IEP	Enrichment
MF	GO:0032553	ribonucleotide binding	IEP	Enrichment
MF	GO:0032555	purine ribonucleotide binding	IEP	Enrichment
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Enrichment
BP	GO:0033865	nucleoside bisphosphate metabolic process	IEP	Enrichment
BP	GO:0033866	nucleoside bisphosphate biosynthetic process	IEP	Enrichment
BP	GO:0033875	ribonucleoside bisphosphate metabolic process	IEP	Enrichment
BP	GO:0034030	ribonucleoside bisphosphate biosynthetic process	IEP	Enrichment
BP	GO:0034032	purine nucleoside bisphosphate metabolic process	IEP	Enrichment
BP	GO:0034033	purine nucleoside bisphosphate biosynthetic process	IEP	Enrichment
BP	GO:0035556	intracellular signal transduction	IEP	Enrichment
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Enrichment
MF	GO:0036094	small molecule binding	IEP	Enrichment
BP	GO:0036211	protein modification process	IEP	Enrichment
MF	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity	IEP	Enrichment
BP	GO:0042398	cellular modified amino acid biosynthetic process	IEP	Enrichment
BP	GO:0042558	pteridine-containing compound metabolic process	IEP	Enrichment
BP	GO:0042559	pteridine-containing compound biosynthetic process	IEP	Enrichment
MF	GO:0043168	anion binding	IEP	Enrichment
BP	GO:0043412	macromolecule modification	IEP	Enrichment
BP	GO:0044281	small molecule metabolic process	IEP	Enrichment
BP	GO:0046451	diaminopimelate metabolic process	IEP	Enrichment
MF	GO:0050308	sugar-phosphatase activity	IEP	Enrichment
BP	GO:0055086	nucleobase-containing small molecule metabolic process	IEP	Enrichment
BP	GO:0072521	purine-containing compound metabolic process	IEP	Enrichment
MF	GO:0097367	carbohydrate derivative binding	IEP	Enrichment
MF	GO:1901265	nucleoside phosphate binding	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR015886	DNA_glyclase/AP_lyase_DNA-bd	133	223
IPR012319	FPG_cat	1	116
IPR010663	Znf_FPG/IleRS	246	273

External Links

No external refs found!

AKI49561 (mutM, L2625_01670)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation