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  5. AKI49768

AKI49768 (purK, L2625_01910)


Aliases : purK, L2625_01910

Description : phosphoribosylaminoimidazole carboxylase, ATPase subunit [Ensembl]. D-isomer specific 2-hydroxyacid dehydrogenase, ATP-grasp fold, Phosphoribosylaminoimidazole carboxylase [Interproscan].


Gene families : OG_02_0000599 (OrthoFinder) Phylogenetic Tree(s): OG0000599_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: AKI49768
Cluster HCCA: Cluster_10

Target Alias Description ECC score Gene Family Method Actions
AAC73624 purK, b0522 N5-carboxyaminoimidazole ribonucleotide synthase... 0.09 OrthoFinder
AAK98858 spr0054, purK Phosphoribosyl glucinamide formyltransferase [Ensembl].... 0.12 OrthoFinder
AAL19487 STM0533, purK phosphoribosylaminoimidazole carboxylase = AIR... 0.06 OrthoFinder
AEA94185 purK, OG1RF_11498 phosphoribosylaminoimidazole carboxylase ATPase subunit... 0.07 OrthoFinder
AGT25557 N559_3922 phosphoribosylaminoimidazole carboxylase ATPase subunit... 0.07 OrthoFinder
CCG26117 No alias Phosphoribosylaminoimidazole carboxylase ATPase subunit... 0.1 OrthoFinder
CPC41036 purK, ERS093114_00359 Phosphoribosylaminoimidazole carboxylase ATPase subunit... 0.13 OrthoFinder
CRP05042 purK N5-carboxyaminoimidazole ribonucleotide synthase... 0.07 OrthoFinder
EDJ90912 CGSHi22421_03648 phosphoribosylaminoimidazole carboxylase [Ensembl]. 0.05 OrthoFinder
KNA53679 VCV51_030034 phosphoribosylaminoimidazole carboxylase [Ensembl].... 0.08 OrthoFinder

Type GO Term Name Evidence Source
MF GO:0051287 NAD binding IEA Interproscan
BP GO:0055114 obsolete oxidation-reduction process IEA Interproscan
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Type GO Term Name Evidence Source
BP GO:0000105 histidine biosynthetic process IEP Enrichment
MF GO:0003864 3-methyl-2-oxobutanoate hydroxymethyltransferase activity IEP Enrichment
MF GO:0003879 ATP phosphoribosyltransferase activity IEP Enrichment
MF GO:0003937 IMP cyclohydrolase activity IEP Enrichment
MF GO:0004019 adenylosuccinate synthase activity IEP Enrichment
MF GO:0004329 formate-tetrahydrofolate ligase activity IEP Enrichment
MF GO:0004357 glutamate-cysteine ligase activity IEP Enrichment
MF GO:0004399 histidinol dehydrogenase activity IEP Enrichment
MF GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity IEP Enrichment
MF GO:0004592 pantoate-beta-alanine ligase activity IEP Enrichment
MF GO:0004637 phosphoribosylamine-glycine ligase activity IEP Enrichment
MF GO:0004643 phosphoribosylaminoimidazolecarboxamide formyltransferase activity IEP Enrichment
MF GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor IEP Enrichment
BP GO:0006139 nucleobase-containing compound metabolic process IEP Enrichment
BP GO:0006144 purine nucleobase metabolic process IEP Enrichment
BP GO:0006163 purine nucleotide metabolic process IEP Enrichment
BP GO:0006164 purine nucleotide biosynthetic process IEP Enrichment
BP GO:0006188 IMP biosynthetic process IEP Enrichment
BP GO:0006189 'de novo' IMP biosynthetic process IEP Enrichment
BP GO:0006547 histidine metabolic process IEP Enrichment
BP GO:0006575 cellular modified amino acid metabolic process IEP Enrichment
BP GO:0006725 cellular aromatic compound metabolic process IEP Enrichment
BP GO:0006749 glutathione metabolic process IEP Enrichment
BP GO:0006750 glutathione biosynthetic process IEP Enrichment
BP GO:0006753 nucleoside phosphate metabolic process IEP Enrichment
BP GO:0006793 phosphorus metabolic process IEP Enrichment
BP GO:0006796 phosphate-containing compound metabolic process IEP Enrichment
BP GO:0006807 nitrogen compound metabolic process IEP Enrichment
BP GO:0008152 metabolic process IEP Enrichment
MF GO:0008961 phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity IEP Enrichment
MF GO:0008987 quinolinate synthetase A activity IEP Enrichment
BP GO:0009058 biosynthetic process IEP Enrichment
BP GO:0009113 purine nucleobase biosynthetic process IEP Enrichment
BP GO:0009116 nucleoside metabolic process IEP Enrichment
BP GO:0009117 nucleotide metabolic process IEP Enrichment
BP GO:0009165 nucleotide biosynthetic process IEP Enrichment
BP GO:0009262 deoxyribonucleotide metabolic process IEP Enrichment
BP GO:0009263 deoxyribonucleotide biosynthetic process IEP Enrichment
BP GO:0009435 NAD biosynthetic process IEP Enrichment
BP GO:0009987 cellular process IEP Enrichment
MF GO:0010181 FMN binding IEP Enrichment
MF GO:0015035 protein-disulfide reductase activity IEP Enrichment
MF GO:0015036 disulfide oxidoreductase activity IEP Enrichment
BP GO:0015939 pantothenate metabolic process IEP Enrichment
BP GO:0015940 pantothenate biosynthetic process IEP Enrichment
BP GO:0016053 organic acid biosynthetic process IEP Enrichment
MF GO:0016742 hydroxymethyl-, formyl- and related transferase activity IEP Enrichment
MF GO:0016757 glycosyltransferase activity IEP Enrichment
MF GO:0016763 pentosyltransferase activity IEP Enrichment
MF GO:0016874 ligase activity IEP Enrichment
MF GO:0016879 ligase activity, forming carbon-nitrogen bonds IEP Enrichment
MF GO:0016881 acid-amino acid ligase activity IEP Enrichment
BP GO:0018130 heterocycle biosynthetic process IEP Enrichment
BP GO:0019184 nonribosomal peptide biosynthetic process IEP Enrichment
BP GO:0019359 nicotinamide nucleotide biosynthetic process IEP Enrichment
BP GO:0019362 pyridine nucleotide metabolic process IEP Enrichment
BP GO:0019363 pyridine nucleotide biosynthetic process IEP Enrichment
BP GO:0019438 aromatic compound biosynthetic process IEP Enrichment
BP GO:0019637 organophosphate metabolic process IEP Enrichment
BP GO:0032787 monocarboxylic acid metabolic process IEP Enrichment
BP GO:0034641 cellular nitrogen compound metabolic process IEP Enrichment
BP GO:0034654 nucleobase-containing compound biosynthetic process IEP Enrichment
BP GO:0042157 lipoprotein metabolic process IEP Enrichment
BP GO:0042158 lipoprotein biosynthetic process IEP Enrichment
BP GO:0042398 cellular modified amino acid biosynthetic process IEP Enrichment
BP GO:0044237 cellular metabolic process IEP Enrichment
BP GO:0044249 cellular biosynthetic process IEP Enrichment
BP GO:0044271 cellular nitrogen compound biosynthetic process IEP Enrichment
BP GO:0044281 small molecule metabolic process IEP Enrichment
BP GO:0046040 IMP metabolic process IEP Enrichment
BP GO:0046394 carboxylic acid biosynthetic process IEP Enrichment
BP GO:0046483 heterocycle metabolic process IEP Enrichment
BP GO:0046496 nicotinamide nucleotide metabolic process IEP Enrichment
BP GO:0055086 nucleobase-containing small molecule metabolic process IEP Enrichment
MF GO:0061731 ribonucleoside-diphosphate reductase activity IEP Enrichment
BP GO:0071704 organic substance metabolic process IEP Enrichment
BP GO:0072330 monocarboxylic acid biosynthetic process IEP Enrichment
BP GO:0072521 purine-containing compound metabolic process IEP Enrichment
BP GO:0072522 purine-containing compound biosynthetic process IEP Enrichment
BP GO:0072524 pyridine-containing compound metabolic process IEP Enrichment
BP GO:0072525 pyridine-containing compound biosynthetic process IEP Enrichment
BP GO:0090407 organophosphate biosynthetic process IEP Enrichment
BP GO:1901135 carbohydrate derivative metabolic process IEP Enrichment
BP GO:1901293 nucleoside phosphate biosynthetic process IEP Enrichment
BP GO:1901360 organic cyclic compound metabolic process IEP Enrichment
BP GO:1901362 organic cyclic compound biosynthetic process IEP Enrichment
BP GO:1901564 organonitrogen compound metabolic process IEP Enrichment
BP GO:1901566 organonitrogen compound biosynthetic process IEP Enrichment
BP GO:1901576 organic substance biosynthetic process IEP Enrichment
BP GO:1901657 glycosyl compound metabolic process IEP Enrichment
InterPro domains Description Start Stop
IPR006140 D-isomer_DH_NAD-bd 7 76
IPR003135 ATP-grasp_carboxylate-amine 116 285
IPR040686 PurK_C 312 364
No external refs found!