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GO:0016874: ligase activity (Molecular function)

"Catalysis of the joining of two molecules, or two groups within a single molecule, using the energy from the hydrolysis of ATP, a similar triphosphate, or a pH gradient." [EC:6.-.-.-, GOC:mah]


There are 3931 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_14 Campylobacter jejuni 9.09 % 0.000786 0.044812
Cluster_2 Clostridioides difficile 4.07 % 0.000163 0.001278
Cluster_12 Enterococcus faecalis 9.33 % 8.1e-05 0.00094
Cluster_23 Escherichia coli 10.87 % 0.000312 0.006204
Cluster_37 Escherichia coli 11.21 % 0.0 0.0
Cluster_26 Klebsiella pneumoniae 5.71 % 0.000663 0.006938
Cluster_44 Klebsiella pneumoniae 8.21 % 0.0 1e-06
Cluster_12 Klebsiella pneumoniae 5.88 % 0.005038 0.013041
Cluster_18 Listeria monocytogenes 12.88 % 0.0 0.0
Cluster_42 Mycobacterium tuberculosis 7.84 % 0.000902 0.037437
Cluster_12 Neisseria gonorrhoeae 10.46 % 0.0 0.0
Cluster_73 Pseudomonas aeruginosa 50.0 % 0.019561 0.046946
Cluster_24 Pseudomonas aeruginosa 7.55 % 0.001732 0.011824
Cluster_47 Pseudomonas aeruginosa 5.52 % 7.7e-05 0.002954
Cluster_51 Pseudomonas aeruginosa 5.95 % 0.00133 0.007065
Cluster_35 Pseudomonas aeruginosa 3.5 % 0.003271 0.022482
Cluster_47 Salmonella enterica 12.24 % 2.2e-05 0.00412
Cluster_31 Salmonella enterica 6.73 % 0.0 1e-06
Cluster_5 Staphylococcus aureus 4.86 % 0.000927 0.00762
Cluster_14 Staphylococcus aureus 14.04 % 1e-06 9.9e-05
Cluster_4 Streptococcus pyogenes 5.24 % 0.000628 0.004144
Cluster_12 Vibrio cholerae 4.95 % 5.1e-05 0.007828
Sequences (3931) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms