AKP15454 (nth, WX61_01408)

Aliases : nth, WX61_01408

Description : Endonuclease III [Ensembl]. Helix-hairpin-helix motif, Iron-sulfur binding domain of endonuclease III, HhH-GPD superfamily base excision DNA repair protein [Interproscan].

Gene families : OG_02_0000527 (OrthoFinder) Phylogenetic Tree(s): OG0000527_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AKP15454
Cluster	HCCA: Cluster_16

Target	Alias	Description	ECC score	Gene Family Method	Actions
AEA93619	nth, OG1RF_10932	endonuclease III [Ensembl]. Helix-hairpin-helix motif,...	0.04	OrthoFinder
KNA56243	VCV51_032979	endonuclease III [Ensembl]. Helix-hairpin-helix motif,...	0.05	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	None	Extended
BP	GO:0006284	base-excision repair	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
MF	GO:0051536	iron-sulfur cluster binding	None	Extended
MF	GO:0051539	4 iron, 4 sulfur cluster binding	IEA	Interproscan
MF	GO:0051540	metal cluster binding	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEP	Enrichment
MF	GO:0003824	catalytic activity	IEP	Enrichment
MF	GO:0003842	1-pyrroline-5-carboxylate dehydrogenase activity	IEP	Enrichment
MF	GO:0004127	cytidylate kinase activity	IEP	Enrichment
MF	GO:0004358	glutamate N-acetyltransferase activity	IEP	Enrichment
MF	GO:0004375	glycine dehydrogenase (decarboxylating) activity	IEP	Enrichment
MF	GO:0004386	helicase activity	IEP	Enrichment
MF	GO:0004424	imidazoleglycerol-phosphate dehydratase activity	IEP	Enrichment
MF	GO:0004611	phosphoenolpyruvate carboxykinase activity	IEP	Enrichment
MF	GO:0005515	protein binding	IEP	Enrichment
MF	GO:0005524	ATP binding	IEP	Enrichment
CC	GO:0005694	chromosome	IEP	Enrichment
BP	GO:0006082	organic acid metabolic process	IEP	Enrichment
BP	GO:0006544	glycine metabolic process	IEP	Enrichment
BP	GO:0006546	glycine catabolic process	IEP	Enrichment
MF	GO:0008080	N-acetyltransferase activity	IEP	Enrichment
MF	GO:0008094	ATPase, acting on DNA	IEP	Enrichment
MF	GO:0008964	phosphoenolpyruvate carboxylase activity	IEP	Enrichment
BP	GO:0009063	cellular amino acid catabolic process	IEP	Enrichment
BP	GO:0009071	serine family amino acid catabolic process	IEP	Enrichment
BP	GO:0015977	carbon fixation	IEP	Enrichment
BP	GO:0016053	organic acid biosynthetic process	IEP	Enrichment
BP	GO:0016054	organic acid catabolic process	IEP	Enrichment
MF	GO:0016407	acetyltransferase activity	IEP	Enrichment
MF	GO:0016410	N-acyltransferase activity	IEP	Enrichment
MF	GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	IEP	Enrichment
MF	GO:0016642	oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor	IEP	Enrichment
MF	GO:0016746	acyltransferase activity	IEP	Enrichment
MF	GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	IEP	Enrichment
MF	GO:0016787	hydrolase activity	IEP	Enrichment
MF	GO:0017076	purine nucleotide binding	IEP	Enrichment
BP	GO:0019752	carboxylic acid metabolic process	IEP	Enrichment
MF	GO:0030554	adenyl nucleotide binding	IEP	Enrichment
MF	GO:0032553	ribonucleotide binding	IEP	Enrichment
MF	GO:0032555	purine ribonucleotide binding	IEP	Enrichment
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Enrichment
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Enrichment
MF	GO:0036094	small molecule binding	IEP	Enrichment
MF	GO:0043167	ion binding	IEP	Enrichment
MF	GO:0043168	anion binding	IEP	Enrichment
BP	GO:0043436	oxoacid metabolic process	IEP	Enrichment
BP	GO:0046394	carboxylic acid biosynthetic process	IEP	Enrichment
BP	GO:0046395	carboxylic acid catabolic process	IEP	Enrichment
MF	GO:0097367	carbohydrate derivative binding	IEP	Enrichment
MF	GO:0140097	catalytic activity, acting on DNA	IEP	Enrichment
MF	GO:1901265	nucleoside phosphate binding	IEP	Enrichment
BP	GO:1901606	alpha-amino acid catabolic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR000445	HhH_motif	110	138
IPR003651	Endonuclease3_FeS-loop_motif	198	214
IPR003265	HhH-GPD_domain	45	179

External Links

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AKP15454 (nth, WX61_01408)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation