CCL18232 (mutL, BN171_2170019)

Aliases : mutL, BN171_2170019

Description : DNA mismatch repair protein MutL [Ensembl]. MutL C terminal dimerisation domain, Histidine kinase-, DNA mismatch repair protein [Interproscan].

Gene families : OG_02_0000756 (OrthoFinder) Phylogenetic Tree(s): OG0000756_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: CCL18232
Cluster	HCCA: Cluster_8

Target	Alias	Description	ECC score	Gene Family Method
AAL23179	STM4359, mutL	enzyme in methyl-directed mismatch repair [Ensembl]....	0.03	OrthoFinder
AEA95121	hexB, OG1RF_12434	DNA mismatch repair protein HexB [Ensembl]. Histidine...	0.03	OrthoFinder
AKP16198	mutL, WX61_02174	DNA mismatch repair protein MutL [Ensembl]. Histidine...	0.03	OrthoFinder
CPC34369	mutL, ERS093114_00128	DNA mismatch repair protein MutL [Ensembl]. Histidine...	0.04	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	None	Extended
MF	GO:0003690	double-stranded DNA binding	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	None	Extended
BP	GO:0006298	mismatch repair	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0030983	mismatched DNA binding	IEA	Interproscan
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003697	single-stranded DNA binding	IEP	Enrichment
MF	GO:0004127	cytidylate kinase activity	IEP	Enrichment
MF	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	IEP	Enrichment
BP	GO:0006081	cellular aldehyde metabolic process	IEP	Enrichment
BP	GO:0006260	DNA replication	IEP	Enrichment
BP	GO:0006396	RNA processing	IEP	Enrichment
BP	GO:0006777	Mo-molybdopterin cofactor biosynthetic process	IEP	Enrichment
MF	GO:0008113	peptide-methionine (S)-S-oxide reductase activity	IEP	Enrichment
MF	GO:0008408	3'-5' exonuclease activity	IEP	Enrichment
BP	GO:0009240	isopentenyl diphosphate biosynthetic process	IEP	Enrichment
MF	GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	IEP	Enrichment
MF	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor	IEP	Enrichment
MF	GO:0016728	oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor	IEP	Enrichment
MF	GO:0016776	phosphotransferase activity, phosphate group as acceptor	IEP	Enrichment
CC	GO:0019008	molybdopterin synthase complex	IEP	Enrichment
MF	GO:0019205	nucleobase-containing compound kinase activity	IEP	Enrichment
BP	GO:0019288	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway	IEP	Enrichment
BP	GO:0019682	glyceraldehyde-3-phosphate metabolic process	IEP	Enrichment
BP	GO:0019720	Mo-molybdopterin cofactor metabolic process	IEP	Enrichment
CC	GO:0032991	protein-containing complex	IEP	Enrichment
MF	GO:0033743	peptide-methionine (R)-S-oxide reductase activity	IEP	Enrichment
BP	GO:0034645	cellular macromolecule biosynthetic process	IEP	Enrichment
BP	GO:0043545	molybdopterin cofactor metabolic process	IEP	Enrichment
BP	GO:0046490	isopentenyl diphosphate metabolic process	IEP	Enrichment
MF	GO:0050145	nucleoside monophosphate kinase activity	IEP	Enrichment
BP	GO:0050992	dimethylallyl diphosphate biosynthetic process	IEP	Enrichment
BP	GO:0050993	dimethylallyl diphosphate metabolic process	IEP	Enrichment
BP	GO:0051189	prosthetic group metabolic process	IEP	Enrichment
MF	GO:0061731	ribonucleoside-diphosphate reductase activity	IEP	Enrichment
MF	GO:0070402	NADPH binding	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR013507	DNA_mismatch_S5_2-like	210	324
IPR014790	MutL_C	471	610

External Links

UniProtKB	U3WW23

CCL18232 (mutL, BN171_2170019)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation