AAL19195 (STM0231, dnaE)

Aliases : STM0231, dnaE

Description : DNA polymerase III, alpha subunit [Ensembl]. PHP domain, Helix-hairpin-helix motif, OB-fold nucleic acid binding domain, Bacterial DNA polymerase III alpha NTPase domain, Bacterial DNA polymerase III alpha subunit finger domain [Interproscan].

Gene families : OG_02_0000325 (OrthoFinder) Phylogenetic Tree(s): OG0000325_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AAL19195
Cluster	HCCA: Cluster_47

Target	Alias	Description	ECC score	Gene Family Method
AAC73295	dnaE, b0184	DNA polymerase III alpha subunit [Ensembl]. PHP domain,...	0.19	OrthoFinder
AEA93464	dnaE, OG1RF_10777	DNA-directed DNA polymerase III alpha subunit [Ensembl]....	0.03	OrthoFinder
AGT25840	N559_4216	DNA polymerase III subunit alpha [Ensembl]. Bacterial...	0.08	OrthoFinder
AKP15394	dnaE, WX61_01347	DNA polymerase III subunit alpha [Ensembl]. PHP domain,...	0.04	OrthoFinder
CCG26417	No alias	DNA polymerase III alpha subunit [Ensembl]. PHP domain,...	0.03	OrthoFinder
CRO13404	dnaE	DNA polymerase III subunit alpha [Ensembl]. PHP domain,...	0.05	OrthoFinder
KNA51808	VCV51_031511	DNA polymerase III [Ensembl]. PHP domain,...	0.05	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	IEA	Interproscan
MF	GO:0003824	catalytic activity	IEA	Interproscan
MF	GO:0004518	nuclease activity	None	Extended
MF	GO:0004527	exonuclease activity	None	Extended
MF	GO:0005488	binding	None	Extended
BP	GO:0006260	DNA replication	IEA	Interproscan
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008408	3'-5' exonuclease activity	IEA	Interproscan
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009059	macromolecule biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016788	hydrolase activity, acting on ester bonds	None	Extended
BP	GO:0034645	cellular macromolecule biosynthetic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEP	Enrichment
BP	GO:0001522	pseudouridine synthesis	IEP	Enrichment
MF	GO:0003723	RNA binding	IEP	Enrichment
MF	GO:0003919	FMN adenylyltransferase activity	IEP	Enrichment
MF	GO:0004107	chorismate synthase activity	IEP	Enrichment
MF	GO:0005524	ATP binding	IEP	Enrichment
MF	GO:0005525	GTP binding	IEP	Enrichment
BP	GO:0006081	cellular aldehyde metabolic process	IEP	Enrichment
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	Enrichment
BP	GO:0006281	DNA repair	IEP	Enrichment
BP	GO:0006629	lipid metabolic process	IEP	Enrichment
BP	GO:0006643	membrane lipid metabolic process	IEP	Enrichment
BP	GO:0006644	phospholipid metabolic process	IEP	Enrichment
BP	GO:0006664	glycolipid metabolic process	IEP	Enrichment
BP	GO:0006721	terpenoid metabolic process	IEP	Enrichment
BP	GO:0006725	cellular aromatic compound metabolic process	IEP	Enrichment
BP	GO:0006807	nitrogen compound metabolic process	IEP	Enrichment
BP	GO:0006974	cellular response to DNA damage stimulus	IEP	Enrichment
MF	GO:0008168	methyltransferase activity	IEP	Enrichment
MF	GO:0008171	O-methyltransferase activity	IEP	Enrichment
MF	GO:0008175	tRNA methyltransferase activity	IEP	Enrichment
MF	GO:0008194	UDP-glycosyltransferase activity	IEP	Enrichment
MF	GO:0008417	fucosyltransferase activity	IEP	Enrichment
MF	GO:0008531	riboflavin kinase activity	IEP	Enrichment
BP	GO:0008610	lipid biosynthetic process	IEP	Enrichment
BP	GO:0008654	phospholipid biosynthetic process	IEP	Enrichment
MF	GO:0008685	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity	IEP	Enrichment
MF	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	IEP	Enrichment
MF	GO:0008915	lipid-A-disaccharide synthase activity	IEP	Enrichment
MF	GO:0008961	phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity	IEP	Enrichment
MF	GO:0009007	site-specific DNA-methyltransferase (adenine-specific) activity	IEP	Enrichment
MF	GO:0009008	DNA-methyltransferase activity	IEP	Enrichment
MF	GO:0009020	tRNA (guanosine-2'-O-)-methyltransferase activity	IEP	Enrichment
MF	GO:0009029	tetraacyldisaccharide 4'-kinase activity	IEP	Enrichment
BP	GO:0009073	aromatic amino acid family biosynthetic process	IEP	Enrichment
BP	GO:0009240	isopentenyl diphosphate biosynthetic process	IEP	Enrichment
BP	GO:0009245	lipid A biosynthetic process	IEP	Enrichment
BP	GO:0009246	enterobacterial common antigen biosynthetic process	IEP	Enrichment
BP	GO:0009247	glycolipid biosynthetic process	IEP	Enrichment
BP	GO:0009311	oligosaccharide metabolic process	IEP	Enrichment
BP	GO:0009312	oligosaccharide biosynthetic process	IEP	Enrichment
CC	GO:0009360	DNA polymerase III complex	IEP	Enrichment
BP	GO:0009451	RNA modification	IEP	Enrichment
MF	GO:0009982	pseudouridine synthase activity	IEP	Enrichment
BP	GO:0016051	carbohydrate biosynthetic process	IEP	Enrichment
BP	GO:0016070	RNA metabolic process	IEP	Enrichment
BP	GO:0016114	terpenoid biosynthetic process	IEP	Enrichment
MF	GO:0016423	tRNA (guanine) methyltransferase activity	IEP	Enrichment
MF	GO:0016726	oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor	IEP	Enrichment
MF	GO:0016740	transferase activity	IEP	Enrichment
MF	GO:0016741	transferase activity, transferring one-carbon groups	IEP	Enrichment
MF	GO:0016757	glycosyltransferase activity	IEP	Enrichment
MF	GO:0016758	hexosyltransferase activity	IEP	Enrichment
MF	GO:0016838	carbon-oxygen lyase activity, acting on phosphates	IEP	Enrichment
MF	GO:0016849	phosphorus-oxygen lyase activity	IEP	Enrichment
MF	GO:0016866	intramolecular transferase activity	IEP	Enrichment
MF	GO:0017076	purine nucleotide binding	IEP	Enrichment
MF	GO:0019001	guanyl nucleotide binding	IEP	Enrichment
BP	GO:0019288	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway	IEP	Enrichment
BP	GO:0019637	organophosphate metabolic process	IEP	Enrichment
BP	GO:0019682	glyceraldehyde-3-phosphate metabolic process	IEP	Enrichment
MF	GO:0030554	adenyl nucleotide binding	IEP	Enrichment
MF	GO:0032553	ribonucleotide binding	IEP	Enrichment
MF	GO:0032555	purine ribonucleotide binding	IEP	Enrichment
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Enrichment
MF	GO:0032561	guanyl ribonucleotide binding	IEP	Enrichment
BP	GO:0032775	DNA methylation on adenine	IEP	Enrichment
BP	GO:0034641	cellular nitrogen compound metabolic process	IEP	Enrichment
MF	GO:0035596	methylthiotransferase activity	IEP	Enrichment
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Enrichment
BP	GO:0036065	fucosylation	IEP	Enrichment
MF	GO:0036094	small molecule binding	IEP	Enrichment
BP	GO:0042157	lipoprotein metabolic process	IEP	Enrichment
BP	GO:0042158	lipoprotein biosynthetic process	IEP	Enrichment
CC	GO:0042575	DNA polymerase complex	IEP	Enrichment
MF	GO:0043138	3'-5' DNA helicase activity	IEP	Enrichment
MF	GO:0043167	ion binding	IEP	Enrichment
MF	GO:0043168	anion binding	IEP	Enrichment
BP	GO:0043412	macromolecule modification	IEP	Enrichment
BP	GO:0044238	primary metabolic process	IEP	Enrichment
BP	GO:0044255	cellular lipid metabolic process	IEP	Enrichment
BP	GO:0046378	enterobacterial common antigen metabolic process	IEP	Enrichment
BP	GO:0046467	membrane lipid biosynthetic process	IEP	Enrichment
BP	GO:0046483	heterocycle metabolic process	IEP	Enrichment
BP	GO:0046490	isopentenyl diphosphate metabolic process	IEP	Enrichment
BP	GO:0046493	lipid A metabolic process	IEP	Enrichment
MF	GO:0047429	nucleoside-triphosphate diphosphatase activity	IEP	Enrichment
MF	GO:0050497	alkylthioltransferase activity	IEP	Enrichment
BP	GO:0050992	dimethylallyl diphosphate biosynthetic process	IEP	Enrichment
BP	GO:0050993	dimethylallyl diphosphate metabolic process	IEP	Enrichment
MF	GO:0051745	4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity	IEP	Enrichment
CC	GO:0061695	transferase complex, transferring phosphorus-containing groups	IEP	Enrichment
MF	GO:0062105	RNA 2'-O-methyltransferase activity	IEP	Enrichment
BP	GO:0070085	glycosylation	IEP	Enrichment
MF	GO:0070566	adenylyltransferase activity	IEP	Enrichment
BP	GO:0090304	nucleic acid metabolic process	IEP	Enrichment
BP	GO:0090407	organophosphate biosynthetic process	IEP	Enrichment
MF	GO:0097367	carbohydrate derivative binding	IEP	Enrichment
MF	GO:0106050	tRNA 2'-O-methyltransferase activity	IEP	Enrichment
MF	GO:0140097	catalytic activity, acting on DNA	IEP	Enrichment
BP	GO:1901135	carbohydrate derivative metabolic process	IEP	Enrichment
BP	GO:1901137	carbohydrate derivative biosynthetic process	IEP	Enrichment
MF	GO:1901265	nucleoside phosphate binding	IEP	Enrichment
BP	GO:1901269	lipooligosaccharide metabolic process	IEP	Enrichment
BP	GO:1901271	lipooligosaccharide biosynthetic process	IEP	Enrichment
BP	GO:1901360	organic cyclic compound metabolic process	IEP	Enrichment
BP	GO:1903509	liposaccharide metabolic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR004013	PHP_dom	8	171
IPR040982	DNA_pol3_finger	561	735
IPR011708	DNA_pol3_alpha_NTPase_dom	291	558
IPR029460	DNAPol_HHH	808	897
IPR004365	NA-bd_OB_tRNA	1000	1072

External Links

No external refs found!

AAL19195 (STM0231, dnaE)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation