AAL23179 (STM4359, mutL)

Aliases : STM4359, mutL

Description : enzyme in methyl-directed mismatch repair [Ensembl]. Histidine kinase-, DNA mismatch repair protein, MutL C terminal dimerisation domain [Interproscan].

Gene families : OG_02_0000756 (OrthoFinder) Phylogenetic Tree(s): OG0000756_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AAL23179
Cluster	HCCA: Cluster_31

Target	Alias	Description	ECC score	Gene Family Method
AGT26318	N559_4727	DNA mismatch repair protein [Ensembl]. C-terminal...	0.09	OrthoFinder
AKP16198	mutL, WX61_02174	DNA mismatch repair protein MutL [Ensembl]. Histidine...	0.05	OrthoFinder
CCG26322	MutL	DNA mismatch repair protein MutL [Ensembl]. Histidine...	0.03	OrthoFinder
CCL18232	mutL, BN171_2170019	DNA mismatch repair protein MutL [Ensembl]. MutL C...	0.03	OrthoFinder
CRO54409	mutL	DNA mismatch repair protein MutL [Ensembl]. Histidine...	0.04	OrthoFinder
EDJ91210	CGSHi22421_01789	DNA mismatch repair protein [Ensembl]. Histidine...	0.04	OrthoFinder
KNA49104	VCV51_033829, MutL	DNA mismatch repair protein MutL [Ensembl]. Histidine...	0.05	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	None	Extended
MF	GO:0003690	double-stranded DNA binding	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	None	Extended
BP	GO:0006298	mismatch repair	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0030983	mismatched DNA binding	IEA	Interproscan
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003887	DNA-directed DNA polymerase activity	IEP	Enrichment
MF	GO:0004857	enzyme inhibitor activity	IEP	Enrichment
MF	GO:0004866	endopeptidase inhibitor activity	IEP	Enrichment
CC	GO:0005615	extracellular space	IEP	Enrichment
BP	GO:0006364	rRNA processing	IEP	Enrichment
MF	GO:0008897	holo-[acyl-carrier-protein] synthase activity	IEP	Enrichment
MF	GO:0008914	leucyltransferase activity	IEP	Enrichment
BP	GO:0009057	macromolecule catabolic process	IEP	Enrichment
CC	GO:0009360	DNA polymerase III complex	IEP	Enrichment
MF	GO:0015399	primary active transmembrane transporter activity	IEP	Enrichment
BP	GO:0016072	rRNA metabolic process	IEP	Enrichment
MF	GO:0016462	pyrophosphatase activity	IEP	Enrichment
MF	GO:0016740	transferase activity	IEP	Enrichment
MF	GO:0016755	aminoacyltransferase activity	IEP	Enrichment
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	IEP	Enrichment
MF	GO:0016779	nucleotidyltransferase activity	IEP	Enrichment
MF	GO:0016787	hydrolase activity	IEP	Enrichment
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Enrichment
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Enrichment
MF	GO:0016887	ATPase	IEP	Enrichment
BP	GO:0030163	protein catabolic process	IEP	Enrichment
MF	GO:0030414	peptidase inhibitor activity	IEP	Enrichment
MF	GO:0034061	DNA polymerase activity	IEP	Enrichment
BP	GO:0034470	ncRNA processing	IEP	Enrichment
CC	GO:0042575	DNA polymerase complex	IEP	Enrichment
MF	GO:0042626	ATPase-coupled transmembrane transporter activity	IEP	Enrichment
MF	GO:0047429	nucleoside-triphosphate diphosphatase activity	IEP	Enrichment
MF	GO:0061134	peptidase regulator activity	IEP	Enrichment
MF	GO:0061135	endopeptidase regulator activity	IEP	Enrichment
CC	GO:0061695	transferase complex, transferring phosphorus-containing groups	IEP	Enrichment
MF	GO:0140097	catalytic activity, acting on DNA	IEP	Enrichment
BP	GO:1901565	organonitrogen compound catabolic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR013507	DNA_mismatch_S5_2-like	214	330
IPR014790	MutL_C	438	567

External Links

No external refs found!

AAL23179 (STM4359, mutL)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation