Coexpression cluster: Cluster_31 (HCCA)

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Average Expression Profile

Enriched GO Terms (corrected p-value < 0.05) (download table)
ID Label % in cluster Enrichment log2 p-value Corrected p-value
GO:0006139 nucleobase-containing compound metabolic process 17.94% (40/223) 1.85 0.0 0.0
GO:1901360 organic cyclic compound metabolic process 19.28% (43/223) 1.71 0.0 0.0
GO:0006725 cellular aromatic compound metabolic process 18.83% (42/223) 1.71 0.0 0.0
GO:0046483 heterocycle metabolic process 18.83% (42/223) 1.69 0.0 0.0
GO:0090304 nucleic acid metabolic process 13.45% (30/223) 1.89 0.0 0.0
GO:0034641 cellular nitrogen compound metabolic process 18.83% (42/223) 1.48 0.0 0.0
GO:0006807 nitrogen compound metabolic process 23.32% (52/223) 1.26 0.0 0.0
GO:0034660 ncRNA metabolic process 6.73% (15/223) 2.8 0.0 0.0
GO:0097367 carbohydrate derivative binding 16.14% (36/223) 1.55 0.0 0.0
GO:0035639 purine ribonucleoside triphosphate binding 14.8% (33/223) 1.63 0.0 0.0
GO:0017076 purine nucleotide binding 14.8% (33/223) 1.6 0.0 0.0
GO:0005524 ATP binding 13.9% (31/223) 1.67 0.0 0.0
GO:0032559 adenyl ribonucleotide binding 13.9% (31/223) 1.66 0.0 0.0
GO:0043039 tRNA aminoacylation 4.93% (11/223) 3.23 0.0 0.0
GO:0043038 amino acid activation 4.93% (11/223) 3.23 0.0 0.0
GO:0030554 adenyl nucleotide binding 13.9% (31/223) 1.66 0.0 0.0
GO:0043170 macromolecule metabolic process 17.94% (40/223) 1.4 0.0 0.0
GO:0006399 tRNA metabolic process 5.83% (13/223) 2.92 0.0 0.0
GO:0032555 purine ribonucleotide binding 14.8% (33/223) 1.61 0.0 0.0
GO:0016070 RNA metabolic process 8.52% (19/223) 2.24 0.0 0.0
GO:0004812 aminoacyl-tRNA ligase activity 4.93% (11/223) 3.17 0.0 0.0
GO:0016875 ligase activity, forming carbon-oxygen bonds 4.93% (11/223) 3.17 0.0 0.0
GO:0140101 catalytic activity, acting on a tRNA 5.83% (13/223) 2.84 0.0 0.0
GO:0032553 ribonucleotide binding 14.8% (33/223) 1.54 0.0 0.0
GO:0006418 tRNA aminoacylation for protein translation 4.48% (10/223) 3.21 0.0 0.0
GO:0016874 ligase activity 6.73% (15/223) 2.48 0.0 1e-06
GO:0043168 anion binding 16.59% (37/223) 1.38 0.0 1e-06
GO:0000166 nucleotide binding 16.14% (36/223) 1.4 0.0 1e-06
GO:1901265 nucleoside phosphate binding 16.14% (36/223) 1.4 0.0 1e-06
GO:0140098 catalytic activity, acting on RNA 6.73% (15/223) 2.38 0.0 1e-06
GO:0036094 small molecule binding 17.49% (39/223) 1.28 0.0 1e-06
GO:0097159 organic cyclic compound binding 25.56% (57/223) 0.94 0.0 5e-06
GO:1901363 heterocyclic compound binding 25.56% (57/223) 0.94 0.0 5e-06
GO:0071704 organic substance metabolic process 25.11% (56/223) 0.93 1e-06 9e-06
GO:0044238 primary metabolic process 21.97% (49/223) 1.0 1e-06 1.4e-05
GO:0008152 metabolic process 27.8% (62/223) 0.84 1e-06 1.4e-05
GO:0005488 binding 30.49% (68/223) 0.79 1e-06 1.4e-05
GO:0044237 cellular metabolic process 21.52% (48/223) 0.99 2e-06 2e-05
GO:0003723 RNA binding 5.83% (13/223) 2.05 9e-06 0.000118
GO:0043167 ion binding 17.04% (38/223) 1.0 1.8e-05 0.000221
GO:1901564 organonitrogen compound metabolic process 13.45% (30/223) 1.13 2.8e-05 0.000334
GO:0003676 nucleic acid binding 13.9% (31/223) 1.06 5.7e-05 0.000674
GO:0006281 DNA repair 3.14% (7/223) 2.64 7.7e-05 0.000883
GO:0009123 nucleoside monophosphate metabolic process 1.35% (3/223) 4.35 0.000116 0.00108
GO:0000049 tRNA binding 1.35% (3/223) 4.35 0.000116 0.00108
GO:0009124 nucleoside monophosphate biosynthetic process 1.35% (3/223) 4.35 0.000116 0.00108
GO:0009126 purine nucleoside monophosphate metabolic process 1.35% (3/223) 4.35 0.000116 0.00108
GO:0009127 purine nucleoside monophosphate biosynthetic process 1.35% (3/223) 4.35 0.000116 0.00108
GO:0009156 ribonucleoside monophosphate biosynthetic process 1.35% (3/223) 4.35 0.000116 0.00108
GO:0009161 ribonucleoside monophosphate metabolic process 1.35% (3/223) 4.35 0.000116 0.00108
GO:0009167 purine ribonucleoside monophosphate metabolic process 1.35% (3/223) 4.35 0.000116 0.00108
GO:0009168 purine ribonucleoside monophosphate biosynthetic process 1.35% (3/223) 4.35 0.000116 0.00108
GO:0044281 small molecule metabolic process 9.87% (22/223) 1.26 0.000102 0.001143
GO:0006974 cellular response to DNA damage stimulus 3.14% (7/223) 2.46 0.000182 0.001663
GO:0003674 molecular_function 52.91% (118/223) 0.35 0.000245 0.002204
GO:0072522 purine-containing compound biosynthetic process 2.24% (5/223) 2.97 0.000251 0.002213
GO:0033554 cellular response to stress 3.14% (7/223) 2.35 0.000301 0.002607
GO:0003824 catalytic activity 32.74% (73/223) 0.52 0.000322 0.002745
GO:0051716 cellular response to stimulus 3.14% (7/223) 2.3 0.00038 0.003184
GO:0006520 cellular amino acid metabolic process 4.93% (11/223) 1.66 0.000575 0.004737
GO:0050896 response to stimulus 3.59% (8/223) 1.99 0.000685 0.005545
GO:0072521 purine-containing compound metabolic process 2.69% (6/223) 2.35 0.000824 0.006569
GO:0006950 response to stress 3.14% (7/223) 2.07 0.001063 0.008337
GO:0016741 transferase activity, transferring one-carbon groups 4.04% (9/223) 1.69 0.001584 0.012223
GO:0055086 nucleobase-containing small molecule metabolic process 4.04% (9/223) 1.66 0.001796 0.013652
GO:0006259 DNA metabolic process 4.93% (11/223) 1.45 0.001957 0.014429
GO:0009987 cellular process 30.04% (67/223) 0.46 0.001937 0.014497
GO:0004820 glycine-tRNA ligase activity 0.9% (2/223) 4.35 0.002388 0.014744
GO:0030983 mismatched DNA binding 0.9% (2/223) 4.35 0.002388 0.014744
GO:0006426 glycyl-tRNA aminoacylation 0.9% (2/223) 4.35 0.002388 0.014744
GO:0008360 regulation of cell shape 0.9% (2/223) 4.35 0.002388 0.014744
GO:0046040 IMP metabolic process 0.9% (2/223) 4.35 0.002388 0.014744
GO:0022603 regulation of anatomical structure morphogenesis 0.9% (2/223) 4.35 0.002388 0.014744
GO:0003690 double-stranded DNA binding 0.9% (2/223) 4.35 0.002388 0.014744
GO:0006188 IMP biosynthetic process 0.9% (2/223) 4.35 0.002388 0.014744
GO:0050793 regulation of developmental process 0.9% (2/223) 4.35 0.002388 0.014744
GO:0006432 phenylalanyl-tRNA aminoacylation 0.9% (2/223) 4.35 0.002388 0.014744
GO:0022604 regulation of cell morphogenesis 0.9% (2/223) 4.35 0.002388 0.014744
GO:0006164 purine nucleotide biosynthetic process 1.79% (4/223) 2.77 0.00203 0.014744
GO:1901135 carbohydrate derivative metabolic process 4.93% (11/223) 1.4 0.00262 0.015981
GO:0016779 nucleotidyltransferase activity 2.69% (6/223) 2.08 0.002369 0.016962
GO:0006082 organic acid metabolic process 5.38% (12/223) 1.28 0.003515 0.020191
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 1.35% (3/223) 3.13 0.003502 0.020352
GO:0033293 monocarboxylic acid binding 1.35% (3/223) 3.13 0.003502 0.020352
GO:0008144 drug binding 1.35% (3/223) 3.13 0.003502 0.020352
GO:0008658 penicillin binding 1.35% (3/223) 3.13 0.003502 0.020352
GO:0006163 purine nucleotide metabolic process 2.24% (5/223) 2.15 0.004388 0.024913
GO:0016740 transferase activity 11.21% (25/223) 0.79 0.004487 0.025186
GO:0033218 amide binding 1.35% (3/223) 2.94 0.005402 0.029983
GO:0006396 RNA processing 2.69% (6/223) 1.85 0.005467 0.030007
GO:0019752 carboxylic acid metabolic process 4.93% (11/223) 1.24 0.00624 0.033504
GO:0043436 oxoacid metabolic process 4.93% (11/223) 1.24 0.00624 0.033504
GO:0006753 nucleoside phosphate metabolic process 2.69% (6/223) 1.81 0.006334 0.033647
GO:0004826 phenylalanine-tRNA ligase activity 0.9% (2/223) 3.77 0.006931 0.035298
GO:0006298 mismatch repair 0.9% (2/223) 3.77 0.006931 0.035298
GO:0047429 nucleoside-triphosphate diphosphatase activity 0.9% (2/223) 3.77 0.006931 0.035298
GO:0070566 adenylyltransferase activity 0.9% (2/223) 3.77 0.006931 0.035298
GO:0031406 carboxylic acid binding 1.35% (3/223) 2.77 0.007812 0.039381
GO:0008168 methyltransferase activity 3.14% (7/223) 1.57 0.00813 0.040566
GO:0140097 catalytic activity, acting on DNA 3.14% (7/223) 1.54 0.0091 0.044956
Enriched Clades (corrected p-value < 0.05) (download table)
Clade % in cluster Enrichment log2 p-value Corrected p-value Gene Family Method
No enriched Clades found
Similar Clusters (download table)
Species Clustering Method Target Jaccard index Gene Family Method (for comparison) Actions
Campylobacter jejuni HCCA Cluster_1 0.054 OrthoFinder Compare
Campylobacter jejuni HCCA Cluster_7 0.062 OrthoFinder Compare
Campylobacter jejuni HCCA Cluster_8 0.046 OrthoFinder Compare
Clostridioides difficile HCCA Cluster_2 0.031 OrthoFinder Compare
Clostridioides difficile HCCA Cluster_14 0.032 OrthoFinder Compare
Clostridioides difficile HCCA Cluster_19 0.03 OrthoFinder Compare
Clostridioides difficile HCCA Cluster_30 0.047 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_2 0.038 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_7 0.029 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_13 0.034 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_15 0.058 OrthoFinder Compare
Escherichia coli HCCA Cluster_23 0.039 OrthoFinder Compare
Escherichia coli HCCA Cluster_24 0.072 OrthoFinder Compare
Escherichia coli HCCA Cluster_29 0.125 OrthoFinder Compare
Escherichia coli HCCA Cluster_37 0.065 OrthoFinder Compare
Escherichia coli HCCA Cluster_39 0.074 OrthoFinder Compare
Escherichia coli HCCA Cluster_40 0.108 OrthoFinder Compare
Escherichia coli HCCA Cluster_41 0.027 OrthoFinder Compare
Escherichia coli HCCA Cluster_45 0.081 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_3 0.047 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_5 0.037 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_7 0.049 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_11 0.086 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_14 0.029 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_15 0.041 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_19 0.041 OrthoFinder Compare
Helicobacter pylori HCCA Cluster_1 0.029 OrthoFinder Compare
Helicobacter pylori HCCA Cluster_14 0.04 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_2 0.067 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_26 0.13 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_29 0.038 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_37 0.04 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_38 0.031 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_40 0.06 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_42 0.039 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_44 0.078 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_45 0.038 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_46 0.03 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_54 0.031 OrthoFinder Compare
Listeria monocytogenes HCCA Cluster_2 0.027 OrthoFinder Compare
Listeria monocytogenes HCCA Cluster_10 0.048 OrthoFinder Compare
Listeria monocytogenes HCCA Cluster_18 0.055 OrthoFinder Compare
Listeria monocytogenes HCCA Cluster_24 0.059 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_1 0.038 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_7 0.04 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_11 0.034 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_12 0.054 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_16 0.033 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_17 0.034 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_22 0.031 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_22 0.039 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_34 0.04 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_35 0.038 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_40 0.051 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_51 0.052 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_52 0.029 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_53 0.038 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_61 0.045 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_62 0.034 OrthoFinder Compare
Staphylococcus aureus HCCA Cluster_3 0.037 OrthoFinder Compare
Staphylococcus aureus HCCA Cluster_5 0.061 OrthoFinder Compare
Staphylococcus aureus HCCA Cluster_15 0.037 OrthoFinder Compare
Staphylococcus aureus HCCA Cluster_19 0.032 OrthoFinder Compare
Staphylococcus aureus HCCA Cluster_25 0.038 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_2 0.039 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_3 0.032 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_10 0.037 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_14 0.042 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_18 0.059 OrthoFinder Compare
Streptococcus pyogenes HCAA Cluster_4 0.044 OrthoFinder Compare
Streptococcus pyogenes HCAA Cluster_7 0.027 OrthoFinder Compare
Streptococcus pyogenes HCAA Cluster_11 0.059 OrthoFinder Compare
Streptococcus pyogenes HCAA Cluster_14 0.028 OrthoFinder Compare
Streptococcus pyogenes HCAA Cluster_18 0.03 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_1 0.1 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_11 0.069 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_12 0.036 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_19 0.052 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_22 0.027 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_24 0.063 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_31 0.03 OrthoFinder Compare
Sequences (223) (download table)

InterPro Domains

GO Terms

Family Terms