CPC86246 (mutM, ERS093114_01512)

Aliases : mutM, ERS093114_01512

Description : Formamidopyrimidine-DNA glycosylase [Ensembl]. Zinc finger found in FPG and IleRS, Formamidopyrimidine-DNA glycosylase H2TH domain, Formamidopyrimidine-DNA glycosylase N-terminal domain [Interproscan].

Gene families : OG_02_0000689 (OrthoFinder) Phylogenetic Tree(s): OG0000689_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: CPC86246
Cluster	HCCA: Cluster_4

Target	Alias	Description	ECC score	Gene Family Method
AEA93294	mutM, OG1RF_10607	DNA-formamidopyrimidine glycosylase [Ensembl]. Zinc...	0.04	OrthoFinder
AKI49561	mutM, L2625_01670	formamidopyrimidine-DNA glycosylase [Ensembl]. DNA...	0.03	OrthoFinder
AKP14179	mutM, WX61_00090	Formamidopyrimidine-DNA glycosylase [Ensembl]. Zinc...	0.02	OrthoFinder
CCG27151	No alias	Formamidopyrimidine-DNA glycosylase [Ensembl]. Zinc...	0.03	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	None	Extended
MF	GO:0003684	damaged DNA binding	IEA	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	None	Extended
BP	GO:0006284	base-excision repair	IEA	Interproscan
BP	GO:0006289	nucleotide-excision repair	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008270	zinc ion binding	IEA	Interproscan
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016798	hydrolase activity, acting on glycosyl bonds	None	Extended
MF	GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	IEA	Interproscan
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043169	cation binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
MF	GO:0046872	metal ion binding	None	Extended
MF	GO:0046914	transition metal ion binding	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000774	adenyl-nucleotide exchange factor activity	IEP	Enrichment
MF	GO:0003916	DNA topoisomerase activity	IEP	Enrichment
MF	GO:0003918	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity	IEP	Enrichment
MF	GO:0003919	FMN adenylyltransferase activity	IEP	Enrichment
MF	GO:0004140	dephospho-CoA kinase activity	IEP	Enrichment
MF	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	IEP	Enrichment
MF	GO:0004743	pyruvate kinase activity	IEP	Enrichment
MF	GO:0004788	thiamine diphosphokinase activity	IEP	Enrichment
BP	GO:0006091	generation of precursor metabolites and energy	IEP	Enrichment
BP	GO:0006098	pentose-phosphate shunt	IEP	Enrichment
BP	GO:0006265	DNA topological change	IEP	Enrichment
BP	GO:0006739	NADP metabolic process	IEP	Enrichment
BP	GO:0006740	NADPH regeneration	IEP	Enrichment
BP	GO:0006753	nucleoside phosphate metabolic process	IEP	Enrichment
BP	GO:0006793	phosphorus metabolic process	IEP	Enrichment
BP	GO:0006796	phosphate-containing compound metabolic process	IEP	Enrichment
BP	GO:0006996	organelle organization	IEP	Enrichment
MF	GO:0008094	ATPase, acting on DNA	IEP	Enrichment
MF	GO:0008531	riboflavin kinase activity	IEP	Enrichment
BP	GO:0009143	nucleoside triphosphate catabolic process	IEP	Enrichment
BP	GO:0009150	purine ribonucleotide metabolic process	IEP	Enrichment
BP	GO:0009229	thiamine diphosphate biosynthetic process	IEP	Enrichment
BP	GO:0009259	ribonucleotide metabolic process	IEP	Enrichment
BP	GO:0015937	coenzyme A biosynthetic process	IEP	Enrichment
MF	GO:0016301	kinase activity	IEP	Enrichment
BP	GO:0016310	phosphorylation	IEP	Enrichment
MF	GO:0016740	transferase activity	IEP	Enrichment
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	IEP	Enrichment
MF	GO:0016779	nucleotidyltransferase activity	IEP	Enrichment
BP	GO:0018130	heterocycle biosynthetic process	IEP	Enrichment
BP	GO:0019637	organophosphate metabolic process	IEP	Enrichment
BP	GO:0019693	ribose phosphate metabolic process	IEP	Enrichment
MF	GO:0030234	enzyme regulator activity	IEP	Enrichment
MF	GO:0030955	potassium ion binding	IEP	Enrichment
MF	GO:0030975	thiamine binding	IEP	Enrichment
MF	GO:0031420	alkali metal ion binding	IEP	Enrichment
BP	GO:0033866	nucleoside bisphosphate biosynthetic process	IEP	Enrichment
BP	GO:0034030	ribonucleoside bisphosphate biosynthetic process	IEP	Enrichment
BP	GO:0034033	purine nucleoside bisphosphate biosynthetic process	IEP	Enrichment
BP	GO:0042357	thiamine diphosphate metabolic process	IEP	Enrichment
MF	GO:0042802	identical protein binding	IEP	Enrichment
MF	GO:0042803	protein homodimerization activity	IEP	Enrichment
MF	GO:0047429	nucleoside-triphosphate diphosphatase activity	IEP	Enrichment
MF	GO:0051087	chaperone binding	IEP	Enrichment
BP	GO:0051156	glucose 6-phosphate metabolic process	IEP	Enrichment
BP	GO:0051276	chromosome organization	IEP	Enrichment
MF	GO:0051499	D-aminoacyl-tRNA deacylase activity	IEP	Enrichment
BP	GO:0055086	nucleobase-containing small molecule metabolic process	IEP	Enrichment
MF	GO:0060589	nucleoside-triphosphatase regulator activity	IEP	Enrichment
MF	GO:0060590	ATPase regulator activity	IEP	Enrichment
MF	GO:0070566	adenylyltransferase activity	IEP	Enrichment
BP	GO:0071103	DNA conformation change	IEP	Enrichment
BP	GO:0090407	organophosphate biosynthetic process	IEP	Enrichment
MF	GO:0098772	molecular function regulator	IEP	Enrichment
BP	GO:1901362	organic cyclic compound biosynthetic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR012319	FPG_cat	1	135
IPR015886	DNA_glyclase/AP_lyase_DNA-bd	150	242
IPR010663	Znf_FPG/IleRS	264	290

External Links

No external refs found!

CPC86246 (mutM, ERS093114_01512)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation