CPD35390 (mfd, ERS093114_02650)

Aliases : mfd, ERS093114_02650

Description : Transcription-repair coupling factor [Ensembl]. CarD-like/TRCF domain, DEAD/DEAH box helicase, UvrB interaction domain, Helicase conserved C-terminal domain [Interproscan].

Gene families : OG_02_0000637 (OrthoFinder) Phylogenetic Tree(s): OG0000637_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: CPD35390
Cluster	HCCA: Cluster_15

Target	Alias	Description	ECC score	Gene Family Method
AAC74198	mfd, b1114	transcription-repair coupling factor [Ensembl]....	0.03	OrthoFinder
AAK98810	spr0006, mfd	Transcription-repair coupling factor [Ensembl]....	0.07	OrthoFinder
AEA92888	trcF, OG1RF_10201	transcription-repair coupling factor [Ensembl]....	0.05	OrthoFinder
AKP14165	mfd, WX61_00076	Transcription-repair-coupling factor [Ensembl]....	0.04	OrthoFinder
CCL19970	mfd, BN171_3610013	Transcription-repair coupling factor (TRCF ATP-dependent...	0.04	OrthoFinder
CCP43770	mfd, Rv1020	Probable transcription-repair coupling factor Mfd (TRCF)...	0.05	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0002949	tRNA threonylcarbamoyladenosine modification	IEP	Enrichment
MF	GO:0003700	DNA-binding transcription factor activity	IEP	Enrichment
MF	GO:0003824	catalytic activity	IEP	Enrichment
MF	GO:0004045	aminoacyl-tRNA hydrolase activity	IEP	Enrichment
MF	GO:0004150	dihydroneopterin aldolase activity	IEP	Enrichment
MF	GO:0004325	ferrochelatase activity	IEP	Enrichment
MF	GO:0004853	uroporphyrinogen decarboxylase activity	IEP	Enrichment
BP	GO:0006282	regulation of DNA repair	IEP	Enrichment
BP	GO:0006355	regulation of transcription, DNA-templated	IEP	Enrichment
BP	GO:0006778	porphyrin-containing compound metabolic process	IEP	Enrichment
BP	GO:0006779	porphyrin-containing compound biosynthetic process	IEP	Enrichment
BP	GO:0008033	tRNA processing	IEP	Enrichment
MF	GO:0008168	methyltransferase activity	IEP	Enrichment
BP	GO:0009889	regulation of biosynthetic process	IEP	Enrichment
BP	GO:0010468	regulation of gene expression	IEP	Enrichment
BP	GO:0010556	regulation of macromolecule biosynthetic process	IEP	Enrichment
MF	GO:0016740	transferase activity	IEP	Enrichment
MF	GO:0016830	carbon-carbon lyase activity	IEP	Enrichment
BP	GO:0019219	regulation of nucleobase-containing compound metabolic process	IEP	Enrichment
BP	GO:0019222	regulation of metabolic process	IEP	Enrichment
BP	GO:0031323	regulation of cellular metabolic process	IEP	Enrichment
BP	GO:0031326	regulation of cellular biosynthetic process	IEP	Enrichment
BP	GO:0033013	tetrapyrrole metabolic process	IEP	Enrichment
BP	GO:0033014	tetrapyrrole biosynthetic process	IEP	Enrichment
BP	GO:0042558	pteridine-containing compound metabolic process	IEP	Enrichment
BP	GO:0048583	regulation of response to stimulus	IEP	Enrichment
BP	GO:0050789	regulation of biological process	IEP	Enrichment
BP	GO:0050794	regulation of cellular process	IEP	Enrichment
BP	GO:0051052	regulation of DNA metabolic process	IEP	Enrichment
MF	GO:0051082	unfolded protein binding	IEP	Enrichment
BP	GO:0051171	regulation of nitrogen compound metabolic process	IEP	Enrichment
BP	GO:0051252	regulation of RNA metabolic process	IEP	Enrichment
BP	GO:0060255	regulation of macromolecule metabolic process	IEP	Enrichment
BP	GO:0065007	biological regulation	IEP	Enrichment
BP	GO:0070525	tRNA threonylcarbamoyladenosine metabolic process	IEP	Enrichment
BP	GO:0080090	regulation of primary metabolic process	IEP	Enrichment
BP	GO:0080134	regulation of response to stress	IEP	Enrichment
BP	GO:0080135	regulation of cellular response to stress	IEP	Enrichment
MF	GO:0140110	transcription regulator activity	IEP	Enrichment
BP	GO:1903506	regulation of nucleic acid-templated transcription	IEP	Enrichment
BP	GO:2000112	regulation of cellular macromolecule biosynthetic process	IEP	Enrichment
BP	GO:2001020	regulation of response to DNA damage stimulus	IEP	Enrichment
BP	GO:2001141	regulation of RNA biosynthetic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR001650	Helicase_C	817	924
IPR003711	CarD-like/TRCF_domain	495	590
IPR041471	UvrB_inter	139	226
IPR005118	TRCF_C	1021	1113
IPR011545	DEAD/DEAH_box_helicase_dom	620	779

External Links

No external refs found!

CPD35390 (mfd, ERS093114_02650)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation