CCP45388 (ruvB, Rv2592c)

Aliases : ruvB, Rv2592c

Description : Probable holliday junction DNA helicase RuvB [Ensembl]. RuvB AAA lid domain, RuvB C-terminal winged helix domain, Holliday junction DNA helicase RuvB P-loop domain [Interproscan].

Gene families : OG_02_0000389 (OrthoFinder) Phylogenetic Tree(s): OG0000389_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: CCP45388
Cluster	HCCA: Cluster_7

Target	Alias	Description	ECC score	Gene Family Method	Actions
AAC74930	ruvB, b1860	ATP-dependent DNA helicase, component of RuvABC...	0.03	OrthoFinder
KNA58933	VCV51_032623, RuvB	Holliday junction DNA helicase RuvB [Ensembl]. RuvB AAA...	0.02	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	Interproscan
MF	GO:0003678	DNA helicase activity	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004386	helicase activity	None	Extended
MF	GO:0005488	binding	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	IEA	Interproscan
BP	GO:0006310	DNA recombination	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
MF	GO:0008094	ATPase, acting on DNA	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0009378	four-way junction helicase activity	IEA	Interproscan
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016887	ATPase	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000150	DNA strand exchange activity	IEP	Enrichment
MF	GO:0003697	single-stranded DNA binding	IEP	Enrichment
MF	GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	IEP	Enrichment
MF	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity	IEP	Enrichment
MF	GO:0004418	hydroxymethylbilane synthase activity	IEP	Enrichment
MF	GO:0004518	nuclease activity	IEP	Enrichment
MF	GO:0004519	endonuclease activity	IEP	Enrichment
MF	GO:0004520	endodeoxyribonuclease activity	IEP	Enrichment
MF	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	IEP	Enrichment
MF	GO:0005315	inorganic phosphate transmembrane transporter activity	IEP	Enrichment
BP	GO:0006072	glycerol-3-phosphate metabolic process	IEP	Enrichment
BP	GO:0006098	pentose-phosphate shunt	IEP	Enrichment
BP	GO:0006188	IMP biosynthetic process	IEP	Enrichment
BP	GO:0006189	'de novo' IMP biosynthetic process	IEP	Enrichment
BP	GO:0006282	regulation of DNA repair	IEP	Enrichment
BP	GO:0006289	nucleotide-excision repair	IEP	Enrichment
BP	GO:0006721	terpenoid metabolic process	IEP	Enrichment
BP	GO:0006740	NADPH regeneration	IEP	Enrichment
BP	GO:0006817	phosphate ion transport	IEP	Enrichment
MF	GO:0008661	1-deoxy-D-xylulose-5-phosphate synthase activity	IEP	Enrichment
MF	GO:0008716	D-alanine-D-alanine ligase activity	IEP	Enrichment
MF	GO:0008818	cobalamin 5'-phosphate synthase activity	IEP	Enrichment
BP	GO:0009123	nucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009124	nucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009126	purine nucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009127	purine nucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009156	ribonucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009161	ribonucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009167	purine ribonucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009168	purine ribonucleoside monophosphate biosynthetic process	IEP	Enrichment
CC	GO:0009379	Holliday junction helicase complex	IEP	Enrichment
BP	GO:0016043	cellular component organization	IEP	Enrichment
BP	GO:0016114	terpenoid biosynthetic process	IEP	Enrichment
MF	GO:0016744	transketolase or transaldolase activity	IEP	Enrichment
MF	GO:0016787	hydrolase activity	IEP	Enrichment
MF	GO:0016788	hydrolase activity, acting on ester bonds	IEP	Enrichment
BP	GO:0017004	cytochrome complex assembly	IEP	Enrichment
BP	GO:0019438	aromatic compound biosynthetic process	IEP	Enrichment
BP	GO:0022607	cellular component assembly	IEP	Enrichment
BP	GO:0033013	tetrapyrrole metabolic process	IEP	Enrichment
BP	GO:0033014	tetrapyrrole biosynthetic process	IEP	Enrichment
CC	GO:0033202	DNA helicase complex	IEP	Enrichment
BP	GO:0034622	cellular protein-containing complex assembly	IEP	Enrichment
BP	GO:0043933	protein-containing complex subunit organization	IEP	Enrichment
BP	GO:0046040	IMP metabolic process	IEP	Enrichment
BP	GO:0046168	glycerol-3-phosphate catabolic process	IEP	Enrichment
MF	GO:0047952	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity	IEP	Enrichment
BP	GO:0048583	regulation of response to stimulus	IEP	Enrichment
BP	GO:0051052	regulation of DNA metabolic process	IEP	Enrichment
MF	GO:0051073	adenosylcobinamide-GDP ribazoletransferase activity	IEP	Enrichment
BP	GO:0051156	glucose 6-phosphate metabolic process	IEP	Enrichment
BP	GO:0052646	alditol phosphate metabolic process	IEP	Enrichment
BP	GO:0065003	protein-containing complex assembly	IEP	Enrichment
BP	GO:0071840	cellular component organization or biogenesis	IEP	Enrichment
BP	GO:0080134	regulation of response to stress	IEP	Enrichment
BP	GO:0080135	regulation of cellular response to stress	IEP	Enrichment
BP	GO:1901135	carbohydrate derivative metabolic process	IEP	Enrichment
BP	GO:2001020	regulation of response to DNA damage stimulus	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR041445	AAA_lid_4	185	258
IPR008824	RuvB-like_N	24	182
IPR008823	RuvB_C	259	329

External Links

No external refs found!

CCP45388 (ruvB, Rv2592c)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation