CCP46191 (dnaE2, Rv3370c)


Aliases : dnaE2, Rv3370c

Description : Probable DNA polymerase III (alpha chain) DnaE2 (DNA nucleotidyltransferase) [Ensembl]. PHP domain, Helix-hairpin-helix motif, Bacterial DNA polymerase III alpha NTPase domain, Bacterial DNA polymerase III alpha subunit finger domain [Interproscan].


Gene families : OG_02_0000325 (OrthoFinder) Phylogenetic Tree(s): OG0000325_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: CCP46191
Cluster HCCA: Cluster_7

Target Alias Description ECC score Gene Family Method Actions
CPD27156 dnaE, ERS093114_02435 DNA polymerase III alpha subunit [Ensembl]. PHP domain,... 0.02 OrthoFinder
KNA51808 VCV51_031511 DNA polymerase III [Ensembl]. PHP domain,... 0.02 OrthoFinder

Type GO Term Name Evidence Source
MF GO:0003824 catalytic activity IEA Interproscan
BP GO:0006260 DNA replication IEA Interproscan
MF GO:0008408 3'-5' exonuclease activity IEA Interproscan
Type GO Term Name Evidence Source
MF GO:0000150 DNA strand exchange activity IEP Enrichment
MF GO:0003676 nucleic acid binding IEP Enrichment
MF GO:0003677 DNA binding IEP Enrichment
MF GO:0003697 single-stranded DNA binding IEP Enrichment
MF GO:0003887 DNA-directed DNA polymerase activity IEP Enrichment
MF GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity IEP Enrichment
MF GO:0004180 carboxypeptidase activity IEP Enrichment
MF GO:0004185 serine-type carboxypeptidase activity IEP Enrichment
MF GO:0005488 binding IEP Enrichment
MF GO:0005524 ATP binding IEP Enrichment
BP GO:0006139 nucleobase-containing compound metabolic process IEP Enrichment
BP GO:0006259 DNA metabolic process IEP Enrichment
BP GO:0006281 DNA repair IEP Enrichment
BP GO:0006289 nucleotide-excision repair IEP Enrichment
BP GO:0006310 DNA recombination IEP Enrichment
BP GO:0006725 cellular aromatic compound metabolic process IEP Enrichment
BP GO:0006807 nitrogen compound metabolic process IEP Enrichment
BP GO:0006950 response to stress IEP Enrichment
BP GO:0006974 cellular response to DNA damage stimulus IEP Enrichment
MF GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds IEP Enrichment
MF GO:0017076 purine nucleotide binding IEP Enrichment
BP GO:0018142 protein-DNA covalent cross-linking IEP Enrichment
BP GO:0018143 nucleic acid-protein covalent cross-linking IEP Enrichment
MF GO:0030554 adenyl nucleotide binding IEP Enrichment
MF GO:0032553 ribonucleotide binding IEP Enrichment
MF GO:0032555 purine ribonucleotide binding IEP Enrichment
MF GO:0032559 adenyl ribonucleotide binding IEP Enrichment
BP GO:0033554 cellular response to stress IEP Enrichment
MF GO:0034061 DNA polymerase activity IEP Enrichment
BP GO:0034641 cellular nitrogen compound metabolic process IEP Enrichment
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Enrichment
BP GO:0044238 primary metabolic process IEP Enrichment
BP GO:0046483 heterocycle metabolic process IEP Enrichment
BP GO:0050896 response to stimulus IEP Enrichment
BP GO:0051716 cellular response to stimulus IEP Enrichment
BP GO:0090304 nucleic acid metabolic process IEP Enrichment
MF GO:0097159 organic cyclic compound binding IEP Enrichment
MF GO:0097367 carbohydrate derivative binding IEP Enrichment
MF GO:0140097 catalytic activity, acting on DNA IEP Enrichment
BP GO:1901360 organic cyclic compound metabolic process IEP Enrichment
MF GO:1901363 heterocyclic compound binding IEP Enrichment
InterPro domains Description Start Stop
IPR011708 DNA_pol3_alpha_NTPase_dom 338 582
IPR029460 DNAPol_HHH 825 913
IPR040982 DNA_pol3_finger 585 749
IPR004013 PHP_dom 48 219
No external refs found!