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  5. AEA93399

AEA93399 (folD, OG1RF_10712)


Aliases : folD, OG1RF_10712

Description : bifunctional methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cyclohydrolase [Ensembl]. Tetrahydrofolate dehydrogenase/cyclohydrolase [Interproscan].


Gene families : OG_02_0000724 (OrthoFinder) Phylogenetic Tree(s): OG0000724_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: AEA93399
Cluster HCCA: Cluster_13

Target Alias Description ECC score Gene Family Method Actions
AAL19496 STM0542, folD 5,10-methylene-tetrahydrofolate dehydrogenase [Ensembl].... 0.03 OrthoFinder
AKP14964 folD, WX61_00901 Bifunctional protein FolD protein [Ensembl].... 0.02 OrthoFinder
CRP57553 folD Bifunctional protein FolD protein [Ensembl].... 0.03 OrthoFinder

Type GO Term Name Evidence Source
MF GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity IEA Interproscan
BP GO:0055114 obsolete oxidation-reduction process IEA Interproscan
Toggle parental
Type GO Term Name Evidence Source
MF GO:0000166 nucleotide binding IEP Enrichment
MF GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity IEP Enrichment
MF GO:0003951 NAD+ kinase activity IEP Enrichment
MF GO:0004140 dephospho-CoA kinase activity IEP Enrichment
MF GO:0004329 formate-tetrahydrofolate ligase activity IEP Enrichment
MF GO:0004345 glucose-6-phosphate dehydrogenase activity IEP Enrichment
MF GO:0004527 exonuclease activity IEP Enrichment
MF GO:0004529 exodeoxyribonuclease activity IEP Enrichment
MF GO:0004536 deoxyribonuclease activity IEP Enrichment
MF GO:0005488 binding IEP Enrichment
MF GO:0005515 protein binding IEP Enrichment
MF GO:0005524 ATP binding IEP Enrichment
BP GO:0006289 nucleotide-excision repair IEP Enrichment
BP GO:0006308 DNA catabolic process IEP Enrichment
BP GO:0006450 regulation of translational fidelity IEP Enrichment
BP GO:0006741 NADP biosynthetic process IEP Enrichment
MF GO:0008168 methyltransferase activity IEP Enrichment
MF GO:0008270 zinc ion binding IEP Enrichment
MF GO:0008855 exodeoxyribonuclease VII activity IEP Enrichment
CC GO:0009318 exodeoxyribonuclease VII complex IEP Enrichment
BP GO:0015936 coenzyme A metabolic process IEP Enrichment
BP GO:0015937 coenzyme A biosynthetic process IEP Enrichment
MF GO:0016426 tRNA (adenine) methyltransferase activity IEP Enrichment
MF GO:0016429 tRNA (adenine-N1-)-methyltransferase activity IEP Enrichment
MF GO:0016741 transferase activity, transferring one-carbon groups IEP Enrichment
MF GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters IEP Enrichment
MF GO:0016854 racemase and epimerase activity IEP Enrichment
MF GO:0016856 racemase and epimerase activity, acting on hydroxy acids and derivatives IEP Enrichment
MF GO:0016895 exodeoxyribonuclease activity, producing 5'-phosphomonoesters IEP Enrichment
MF GO:0017076 purine nucleotide binding IEP Enrichment
BP GO:0019359 nicotinamide nucleotide biosynthetic process IEP Enrichment
BP GO:0019362 pyridine nucleotide metabolic process IEP Enrichment
BP GO:0019363 pyridine nucleotide biosynthetic process IEP Enrichment
BP GO:0019439 aromatic compound catabolic process IEP Enrichment
MF GO:0030554 adenyl nucleotide binding IEP Enrichment
MF GO:0032553 ribonucleotide binding IEP Enrichment
MF GO:0032555 purine ribonucleotide binding IEP Enrichment
MF GO:0032559 adenyl ribonucleotide binding IEP Enrichment
BP GO:0033866 nucleoside bisphosphate biosynthetic process IEP Enrichment
BP GO:0034030 ribonucleoside bisphosphate biosynthetic process IEP Enrichment
BP GO:0034033 purine nucleoside bisphosphate biosynthetic process IEP Enrichment
BP GO:0034655 nucleobase-containing compound catabolic process IEP Enrichment
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Enrichment
MF GO:0036094 small molecule binding IEP Enrichment
MF GO:0043167 ion binding IEP Enrichment
MF GO:0043168 anion binding IEP Enrichment
BP GO:0044248 cellular catabolic process IEP Enrichment
BP GO:0044270 cellular nitrogen compound catabolic process IEP Enrichment
BP GO:0046496 nicotinamide nucleotide metabolic process IEP Enrichment
BP GO:0046700 heterocycle catabolic process IEP Enrichment
MF GO:0046983 protein dimerization activity IEP Enrichment
MF GO:0050043 lactate racemase activity IEP Enrichment
MF GO:0050661 NADP binding IEP Enrichment
BP GO:0072524 pyridine-containing compound metabolic process IEP Enrichment
BP GO:0072525 pyridine-containing compound biosynthetic process IEP Enrichment
MF GO:0097159 organic cyclic compound binding IEP Enrichment
MF GO:0097367 carbohydrate derivative binding IEP Enrichment
MF GO:0140097 catalytic activity, acting on DNA IEP Enrichment
MF GO:1901265 nucleoside phosphate binding IEP Enrichment
BP GO:1901361 organic cyclic compound catabolic process IEP Enrichment
MF GO:1901363 heterocyclic compound binding IEP Enrichment
InterPro domains Description Start Stop
IPR020630 THF_DH/CycHdrlase_cat_dom 4 119
IPR020631 THF_DH/CycHdrlase_NAD-bd_dom 122 280
No external refs found!