AEA94049 (topA, OG1RF_11362)

Aliases : topA, OG1RF_11362

Description : DNA topoisomerase TopA [Ensembl]. Toprim domain, DNA topoisomerase, Topoisomerase DNA binding C4 zinc finger [Interproscan].

Gene families : OG_02_0000393 (OrthoFinder) Phylogenetic Tree(s): OG0000393_tree

Sequence : coding (download), protein (download)

Download

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AEA94049
Cluster	HCCA: Cluster_13

Target	Alias	Description	ECC score	Gene Family Method	Actions
AKP15097	topA, WX61_01039	DNA topoisomerase 1 [Ensembl]. Toprim domain, DNA...	0.03	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003916	DNA topoisomerase activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005694	chromosome	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006265	DNA topological change	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006996	organelle organization	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
MF	GO:0016853	isomerase activity	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043228	non-membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043232	intracellular non-membrane-bounded organelle	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0051276	chromosome organization	None	Extended
BP	GO:0071103	DNA conformation change	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
CC	GO:0110165	cellular anatomical entity	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

Toggle parental

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEP	Enrichment
MF	GO:0004127	cytidylate kinase activity	IEP	Enrichment
MF	GO:0005215	transporter activity	IEP	Enrichment
MF	GO:0005524	ATP binding	IEP	Enrichment
BP	GO:0006820	anion transport	IEP	Enrichment
MF	GO:0008509	anion transmembrane transporter activity	IEP	Enrichment
BP	GO:0009116	nucleoside metabolic process	IEP	Enrichment
MF	GO:0015103	inorganic anion transmembrane transporter activity	IEP	Enrichment
MF	GO:0015291	secondary active transmembrane transporter activity	IEP	Enrichment
BP	GO:0015698	inorganic anion transport	IEP	Enrichment
MF	GO:0017076	purine nucleotide binding	IEP	Enrichment
MF	GO:0022804	active transmembrane transporter activity	IEP	Enrichment
MF	GO:0022857	transmembrane transporter activity	IEP	Enrichment
MF	GO:0030170	pyridoxal phosphate binding	IEP	Enrichment
MF	GO:0030554	adenyl nucleotide binding	IEP	Enrichment
MF	GO:0032553	ribonucleotide binding	IEP	Enrichment
MF	GO:0032555	purine ribonucleotide binding	IEP	Enrichment
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Enrichment
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Enrichment
MF	GO:0036094	small molecule binding	IEP	Enrichment
MF	GO:0042910	xenobiotic transmembrane transporter activity	IEP	Enrichment
MF	GO:0043167	ion binding	IEP	Enrichment
MF	GO:0043168	anion binding	IEP	Enrichment
MF	GO:0070279	vitamin B6 binding	IEP	Enrichment
MF	GO:0097367	carbohydrate derivative binding	IEP	Enrichment
MF	GO:1901265	nucleoside phosphate binding	IEP	Enrichment
BP	GO:1901657	glycosyl compound metabolic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR006171	TOPRIM_domain	6	114
IPR013497	Topo_IA_cen	129	549
IPR013498	Topo_IA_Znf	659	683
IPR013498	Topo_IA_Znf	579	613
IPR013498	Topo_IA_Znf	618	656

External Links

No external refs found!

AEA94049 (topA, OG1RF_11362)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation