AAC74219 (rluE, b1135)

Aliases : rluE, b1135

Description : 23S rRNA pseudouridine(2457) synthase [Ensembl]. RNA pseudouridylate synthase [Interproscan].

Gene families : OG_02_0002290 (OrthoFinder) Phylogenetic Tree(s): OG0002290_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AAC74219
Cluster	HCCA: Cluster_47

Target	Alias	Description	ECC score	Gene Family Method
AAL20166	STM1237, ymfC	putative ribosomal large subunit pseudouridine synthase...	0.03	OrthoFinder
AGT24812	N559_3152	pseudouridine synthase [Ensembl].	0.06	OrthoFinder
CRP36736	rluE	Ribosomal large subunit pseudouridine synthase E...	0.04	OrthoFinder

Type	GO Term	Name	Evidence	Source
BP	GO:0001522	pseudouridine synthesis	IEA	Interproscan
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003723	RNA binding	IEA	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005488	binding	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009451	RNA modification	IEA	Interproscan
MF	GO:0009982	pseudouridine synthase activity	IEA	Interproscan
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
MF	GO:0016853	isomerase activity	None	Extended
MF	GO:0016866	intramolecular transferase activity	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043412	macromolecule modification	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000154	rRNA modification	IEP	Enrichment
BP	GO:0001510	RNA methylation	IEP	Enrichment
MF	GO:0003747	translation release factor activity	IEP	Enrichment
MF	GO:0003951	NAD+ kinase activity	IEP	Enrichment
MF	GO:0004140	dephospho-CoA kinase activity	IEP	Enrichment
MF	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity	IEP	Enrichment
MF	GO:0004529	exodeoxyribonuclease activity	IEP	Enrichment
MF	GO:0004852	uroporphyrinogen-III synthase activity	IEP	Enrichment
BP	GO:0006415	translational termination	IEP	Enrichment
BP	GO:0006739	NADP metabolic process	IEP	Enrichment
BP	GO:0006741	NADP biosynthetic process	IEP	Enrichment
BP	GO:0006753	nucleoside phosphate metabolic process	IEP	Enrichment
BP	GO:0006793	phosphorus metabolic process	IEP	Enrichment
BP	GO:0006796	phosphate-containing compound metabolic process	IEP	Enrichment
MF	GO:0008079	translation termination factor activity	IEP	Enrichment
MF	GO:0008649	rRNA methyltransferase activity	IEP	Enrichment
MF	GO:0008855	exodeoxyribonuclease VII activity	IEP	Enrichment
MF	GO:0008961	phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity	IEP	Enrichment
BP	GO:0009117	nucleotide metabolic process	IEP	Enrichment
BP	GO:0009165	nucleotide biosynthetic process	IEP	Enrichment
BP	GO:0009435	NAD biosynthetic process	IEP	Enrichment
BP	GO:0010035	response to inorganic substance	IEP	Enrichment
BP	GO:0010038	response to metal ion	IEP	Enrichment
BP	GO:0015936	coenzyme A metabolic process	IEP	Enrichment
BP	GO:0015937	coenzyme A biosynthetic process	IEP	Enrichment
MF	GO:0016740	transferase activity	IEP	Enrichment
MF	GO:0016757	glycosyltransferase activity	IEP	Enrichment
MF	GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	IEP	Enrichment
MF	GO:0016895	exodeoxyribonuclease activity, producing 5'-phosphomonoesters	IEP	Enrichment
BP	GO:0018130	heterocycle biosynthetic process	IEP	Enrichment
BP	GO:0019359	nicotinamide nucleotide biosynthetic process	IEP	Enrichment
BP	GO:0019362	pyridine nucleotide metabolic process	IEP	Enrichment
BP	GO:0019363	pyridine nucleotide biosynthetic process	IEP	Enrichment
BP	GO:0019438	aromatic compound biosynthetic process	IEP	Enrichment
BP	GO:0019637	organophosphate metabolic process	IEP	Enrichment
BP	GO:0022411	cellular component disassembly	IEP	Enrichment
BP	GO:0031167	rRNA methylation	IEP	Enrichment
BP	GO:0032984	protein-containing complex disassembly	IEP	Enrichment
BP	GO:0033865	nucleoside bisphosphate metabolic process	IEP	Enrichment
BP	GO:0033866	nucleoside bisphosphate biosynthetic process	IEP	Enrichment
BP	GO:0033875	ribonucleoside bisphosphate metabolic process	IEP	Enrichment
BP	GO:0034030	ribonucleoside bisphosphate biosynthetic process	IEP	Enrichment
BP	GO:0034032	purine nucleoside bisphosphate metabolic process	IEP	Enrichment
BP	GO:0034033	purine nucleoside bisphosphate biosynthetic process	IEP	Enrichment
BP	GO:0034654	nucleobase-containing compound biosynthetic process	IEP	Enrichment
BP	GO:0042157	lipoprotein metabolic process	IEP	Enrichment
BP	GO:0042158	lipoprotein biosynthetic process	IEP	Enrichment
BP	GO:0043414	macromolecule methylation	IEP	Enrichment
BP	GO:0043624	cellular protein complex disassembly	IEP	Enrichment
BP	GO:0043933	protein-containing complex subunit organization	IEP	Enrichment
BP	GO:0044249	cellular biosynthetic process	IEP	Enrichment
BP	GO:0044271	cellular nitrogen compound biosynthetic process	IEP	Enrichment
BP	GO:0046496	nicotinamide nucleotide metabolic process	IEP	Enrichment
BP	GO:0055086	nucleobase-containing small molecule metabolic process	IEP	Enrichment
BP	GO:0070475	rRNA base methylation	IEP	Enrichment
BP	GO:0072524	pyridine-containing compound metabolic process	IEP	Enrichment
BP	GO:0072525	pyridine-containing compound biosynthetic process	IEP	Enrichment
BP	GO:0090407	organophosphate biosynthetic process	IEP	Enrichment
MF	GO:0140102	catalytic activity, acting on a rRNA	IEP	Enrichment
BP	GO:1901293	nucleoside phosphate biosynthetic process	IEP	Enrichment
BP	GO:1901362	organic cyclic compound biosynthetic process	IEP	Enrichment
BP	GO:1901566	organonitrogen compound biosynthetic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR006145	PsdUridine_synth_RsuA/RluA	41	186

External Links

UniProtKB	P75966

AAC74219 (rluE, b1135)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation