AAC76968 (thiC, b3994)

Aliases : thiC, b3994

Description : phosphomethylpyrimidine synthase [Ensembl]. ThiC-associated domain, Radical SAM ThiC family [Interproscan].

Gene families : OG_02_0001139 (OrthoFinder) Phylogenetic Tree(s): OG0001139_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AAC76968
Cluster	HCCA: Cluster_2

Target	Alias	Description	ECC score	Gene Family Method
AAL22992	STM4164, thiC	5'-phosphoryl-5-aminoimidazole [Ensembl]....	0.18	OrthoFinder
AGT26505	N559_4921, ThiC	thiamine biosynthesis protein ThiC [Ensembl]....	0.09	OrthoFinder
CCL17913	thiC, BN171_1940002	Thiamine biosynthesis protein ThiC [Ensembl]. Radical...	0.06	OrthoFinder
KNA53563	VCV51_030044	ThiC family protein [Ensembl]. ThiC-associated domain,...	0.16	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005488	binding	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006766	vitamin metabolic process	None	Extended
BP	GO:0006767	water-soluble vitamin metabolic process	None	Extended
BP	GO:0006772	thiamine metabolic process	None	Extended
BP	GO:0006790	sulfur compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009110	vitamin biosynthetic process	None	Extended
BP	GO:0009228	thiamine biosynthetic process	IEA	Interproscan
BP	GO:0009987	cellular process	None	Extended
BP	GO:0018130	heterocycle biosynthetic process	None	Extended
BP	GO:0019438	aromatic compound biosynthetic process	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0042364	water-soluble vitamin biosynthetic process	None	Extended
BP	GO:0042723	thiamine-containing compound metabolic process	None	Extended
BP	GO:0042724	thiamine-containing compound biosynthetic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044271	cellular nitrogen compound biosynthetic process	None	Extended
BP	GO:0044272	sulfur compound biosynthetic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0044283	small molecule biosynthetic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
MF	GO:0051536	iron-sulfur cluster binding	IEA	Interproscan
MF	GO:0051540	metal cluster binding	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0072527	pyrimidine-containing compound metabolic process	None	Extended
BP	GO:0072528	pyrimidine-containing compound biosynthetic process	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901362	organic cyclic compound biosynthetic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000096	sulfur amino acid metabolic process	IEP	Enrichment
BP	GO:0000097	sulfur amino acid biosynthetic process	IEP	Enrichment
MF	GO:0003824	catalytic activity	IEP	Enrichment
MF	GO:0003852	2-isopropylmalate synthase activity	IEP	Enrichment
MF	GO:0003871	5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity	IEP	Enrichment
MF	GO:0004417	hydroxyethylthiazole kinase activity	IEP	Enrichment
MF	GO:0004425	indole-3-glycerol-phosphate synthase activity	IEP	Enrichment
MF	GO:0004455	ketol-acid reductoisomerase activity	IEP	Enrichment
MF	GO:0004478	methionine adenosyltransferase activity	IEP	Enrichment
MF	GO:0004640	phosphoribosylanthranilate isomerase activity	IEP	Enrichment
MF	GO:0004834	tryptophan synthase activity	IEP	Enrichment
BP	GO:0006082	organic acid metabolic process	IEP	Enrichment
BP	GO:0006520	cellular amino acid metabolic process	IEP	Enrichment
BP	GO:0006534	cysteine metabolic process	IEP	Enrichment
BP	GO:0006536	glutamate metabolic process	IEP	Enrichment
BP	GO:0006537	glutamate biosynthetic process	IEP	Enrichment
BP	GO:0006551	leucine metabolic process	IEP	Enrichment
BP	GO:0006555	methionine metabolic process	IEP	Enrichment
BP	GO:0006556	S-adenosylmethionine biosynthetic process	IEP	Enrichment
BP	GO:0006568	tryptophan metabolic process	IEP	Enrichment
BP	GO:0006576	cellular biogenic amine metabolic process	IEP	Enrichment
BP	GO:0006586	indolalkylamine metabolic process	IEP	Enrichment
MF	GO:0008172	S-methyltransferase activity	IEP	Enrichment
MF	GO:0008641	ubiquitin-like modifier activating enzyme activity	IEP	Enrichment
BP	GO:0008652	cellular amino acid biosynthetic process	IEP	Enrichment
MF	GO:0008987	quinolinate synthetase A activity	IEP	Enrichment
BP	GO:0009072	aromatic amino acid family metabolic process	IEP	Enrichment
BP	GO:0009081	branched-chain amino acid metabolic process	IEP	Enrichment
BP	GO:0009082	branched-chain amino acid biosynthetic process	IEP	Enrichment
BP	GO:0009084	glutamine family amino acid biosynthetic process	IEP	Enrichment
BP	GO:0009086	methionine biosynthetic process	IEP	Enrichment
BP	GO:0009092	homoserine metabolic process	IEP	Enrichment
BP	GO:0009098	leucine biosynthetic process	IEP	Enrichment
BP	GO:0009308	amine metabolic process	IEP	Enrichment
BP	GO:0009435	NAD biosynthetic process	IEP	Enrichment
MF	GO:0015930	glutamate synthase activity	IEP	Enrichment
BP	GO:0016053	organic acid biosynthetic process	IEP	Enrichment
MF	GO:0016491	oxidoreductase activity	IEP	Enrichment
MF	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	IEP	Enrichment
MF	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEP	Enrichment
MF	GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	IEP	Enrichment
MF	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	IEP	Enrichment
BP	GO:0019346	transsulfuration	IEP	Enrichment
BP	GO:0019359	nicotinamide nucleotide biosynthetic process	IEP	Enrichment
BP	GO:0019362	pyridine nucleotide metabolic process	IEP	Enrichment
BP	GO:0019363	pyridine nucleotide biosynthetic process	IEP	Enrichment
BP	GO:0019752	carboxylic acid metabolic process	IEP	Enrichment
MF	GO:0034257	nicotinamide riboside transmembrane transporter activity	IEP	Enrichment
BP	GO:0034258	nicotinamide riboside transport	IEP	Enrichment
MF	GO:0042085	5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity	IEP	Enrichment
BP	GO:0042430	indole-containing compound metabolic process	IEP	Enrichment
BP	GO:0043436	oxoacid metabolic process	IEP	Enrichment
BP	GO:0043650	dicarboxylic acid biosynthetic process	IEP	Enrichment
BP	GO:0044106	cellular amine metabolic process	IEP	Enrichment
BP	GO:0046394	carboxylic acid biosynthetic process	IEP	Enrichment
BP	GO:0046496	nicotinamide nucleotide metabolic process	IEP	Enrichment
BP	GO:0046500	S-adenosylmethionine metabolic process	IEP	Enrichment
BP	GO:0050667	homocysteine metabolic process	IEP	Enrichment
BP	GO:0055114	obsolete oxidation-reduction process	IEP	Enrichment
BP	GO:1901605	alpha-amino acid metabolic process	IEP	Enrichment
BP	GO:1901607	alpha-amino acid biosynthetic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR002817	ThiC/BzaA/B	148	596
IPR025747	ThiC-associated_dom	27	108

External Links

UniProtKB	P30136

AAC76968 (thiC, b3994)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation