AKI49373 (gnd, L2625_01473)

Aliases : gnd, L2625_01473

Description : 6-phosphogluconate dehydrogenase, decarboxylating [Ensembl]. 6-phosphogluconate dehydrogenase [Interproscan].

Gene families : OG_02_0000989 (OrthoFinder) Phylogenetic Tree(s): OG0000989_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AKI49373
Cluster	HCCA: Cluster_20

Target	Alias	Description	ECC score	Gene Family Method	Actions
AEA93469	gnd, OG1RF_10782	phosphogluconate dehydrogenase (decarboxylating)...	0.06	OrthoFinder
AKP15048	gndA, WX61_00986	6-phosphogluconate dehydrogenase, NADP(+)-dependent,...	0.02	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
BP	GO:0006091	generation of precursor metabolites and energy	None	Extended
BP	GO:0006098	pentose-phosphate shunt	IEA	Interproscan
BP	GO:0006739	NADP metabolic process	None	Extended
BP	GO:0006740	NADPH regeneration	None	Extended
BP	GO:0006793	phosphorus metabolic process	None	Extended
BP	GO:0006796	phosphate-containing compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016491	oxidoreductase activity	None	Extended
MF	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	None	Extended
MF	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	None	Extended
BP	GO:0019637	organophosphate metabolic process	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
MF	GO:0050661	NADP binding	IEA	Interproscan
BP	GO:0051156	glucose 6-phosphate metabolic process	None	Extended
BP	GO:0055114	obsolete oxidation-reduction process	IEA	Interproscan
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
BP	GO:1901135	carbohydrate derivative metabolic process	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000413	protein peptidyl-prolyl isomerization	IEP	Enrichment
MF	GO:0003678	DNA helicase activity	IEP	Enrichment
MF	GO:0003755	peptidyl-prolyl cis-trans isomerase activity	IEP	Enrichment
MF	GO:0004146	dihydrofolate reductase activity	IEP	Enrichment
MF	GO:0004177	aminopeptidase activity	IEP	Enrichment
MF	GO:0004325	ferrochelatase activity	IEP	Enrichment
MF	GO:0004345	glucose-6-phosphate dehydrogenase activity	IEP	Enrichment
MF	GO:0004357	glutamate-cysteine ligase activity	IEP	Enrichment
MF	GO:0004386	helicase activity	IEP	Enrichment
MF	GO:0004418	hydroxymethylbilane synthase activity	IEP	Enrichment
MF	GO:0004421	hydroxymethylglutaryl-CoA synthase activity	IEP	Enrichment
MF	GO:0004655	porphobilinogen synthase activity	IEP	Enrichment
MF	GO:0004853	uroporphyrinogen decarboxylase activity	IEP	Enrichment
BP	GO:0006310	DNA recombination	IEP	Enrichment
BP	GO:0006575	cellular modified amino acid metabolic process	IEP	Enrichment
BP	GO:0006720	isoprenoid metabolic process	IEP	Enrichment
BP	GO:0006725	cellular aromatic compound metabolic process	IEP	Enrichment
BP	GO:0006749	glutathione metabolic process	IEP	Enrichment
BP	GO:0006750	glutathione biosynthetic process	IEP	Enrichment
BP	GO:0006778	porphyrin-containing compound metabolic process	IEP	Enrichment
BP	GO:0006779	porphyrin-containing compound biosynthetic process	IEP	Enrichment
BP	GO:0006783	heme biosynthetic process	IEP	Enrichment
BP	GO:0006807	nitrogen compound metabolic process	IEP	Enrichment
MF	GO:0008094	ATPase, acting on DNA	IEP	Enrichment
BP	GO:0008299	isoprenoid biosynthetic process	IEP	Enrichment
BP	GO:0008610	lipid biosynthetic process	IEP	Enrichment
BP	GO:0008616	queuosine biosynthetic process	IEP	Enrichment
BP	GO:0009058	biosynthetic process	IEP	Enrichment
BP	GO:0009119	ribonucleoside metabolic process	IEP	Enrichment
BP	GO:0009163	nucleoside biosynthetic process	IEP	Enrichment
MF	GO:0009378	four-way junction helicase activity	IEP	Enrichment
BP	GO:0009396	folic acid-containing compound biosynthetic process	IEP	Enrichment
BP	GO:0009890	negative regulation of biosynthetic process	IEP	Enrichment
BP	GO:0009892	negative regulation of metabolic process	IEP	Enrichment
BP	GO:0010035	response to inorganic substance	IEP	Enrichment
BP	GO:0010038	response to metal ion	IEP	Enrichment
BP	GO:0010558	negative regulation of macromolecule biosynthetic process	IEP	Enrichment
BP	GO:0010605	negative regulation of macromolecule metabolic process	IEP	Enrichment
MF	GO:0016829	lyase activity	IEP	Enrichment
MF	GO:0016859	cis-trans isomerase activity	IEP	Enrichment
MF	GO:0016887	ATPase	IEP	Enrichment
BP	GO:0018130	heterocycle biosynthetic process	IEP	Enrichment
BP	GO:0018193	peptidyl-amino acid modification	IEP	Enrichment
BP	GO:0018208	peptidyl-proline modification	IEP	Enrichment
BP	GO:0019184	nonribosomal peptide biosynthetic process	IEP	Enrichment
BP	GO:0019438	aromatic compound biosynthetic process	IEP	Enrichment
MF	GO:0019842	vitamin binding	IEP	Enrichment
MF	GO:0030151	molybdenum ion binding	IEP	Enrichment
MF	GO:0030170	pyridoxal phosphate binding	IEP	Enrichment
BP	GO:0031324	negative regulation of cellular metabolic process	IEP	Enrichment
BP	GO:0031327	negative regulation of cellular biosynthetic process	IEP	Enrichment
BP	GO:0033013	tetrapyrrole metabolic process	IEP	Enrichment
BP	GO:0033014	tetrapyrrole biosynthetic process	IEP	Enrichment
BP	GO:0034641	cellular nitrogen compound metabolic process	IEP	Enrichment
BP	GO:0042168	heme metabolic process	IEP	Enrichment
BP	GO:0042398	cellular modified amino acid biosynthetic process	IEP	Enrichment
BP	GO:0042455	ribonucleoside biosynthetic process	IEP	Enrichment
BP	GO:0042559	pteridine-containing compound biosynthetic process	IEP	Enrichment
CC	GO:0042597	periplasmic space	IEP	Enrichment
MF	GO:0043167	ion binding	IEP	Enrichment
MF	GO:0043168	anion binding	IEP	Enrichment
MF	GO:0043169	cation binding	IEP	Enrichment
BP	GO:0044249	cellular biosynthetic process	IEP	Enrichment
BP	GO:0044255	cellular lipid metabolic process	IEP	Enrichment
BP	GO:0044271	cellular nitrogen compound biosynthetic process	IEP	Enrichment
BP	GO:0045892	negative regulation of transcription, DNA-templated	IEP	Enrichment
BP	GO:0045934	negative regulation of nucleobase-containing compound metabolic process	IEP	Enrichment
BP	GO:0046116	queuosine metabolic process	IEP	Enrichment
MF	GO:0046429	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity	IEP	Enrichment
BP	GO:0046483	heterocycle metabolic process	IEP	Enrichment
BP	GO:0046653	tetrahydrofolate metabolic process	IEP	Enrichment
BP	GO:0046654	tetrahydrofolate biosynthetic process	IEP	Enrichment
BP	GO:0046688	response to copper ion	IEP	Enrichment
MF	GO:0046872	metal ion binding	IEP	Enrichment
MF	GO:0046914	transition metal ion binding	IEP	Enrichment
BP	GO:0048519	negative regulation of biological process	IEP	Enrichment
BP	GO:0048523	negative regulation of cellular process	IEP	Enrichment
BP	GO:0050896	response to stimulus	IEP	Enrichment
BP	GO:0051172	negative regulation of nitrogen compound metabolic process	IEP	Enrichment
BP	GO:0051253	negative regulation of RNA metabolic process	IEP	Enrichment
BP	GO:0051775	response to redox state	IEP	Enrichment
MF	GO:0052592	oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor	IEP	Enrichment
MF	GO:0070279	vitamin B6 binding	IEP	Enrichment
BP	GO:1901360	organic cyclic compound metabolic process	IEP	Enrichment
BP	GO:1901362	organic cyclic compound biosynthetic process	IEP	Enrichment
BP	GO:1901564	organonitrogen compound metabolic process	IEP	Enrichment
BP	GO:1901566	organonitrogen compound biosynthetic process	IEP	Enrichment
BP	GO:1901576	organic substance biosynthetic process	IEP	Enrichment
BP	GO:1901659	glycosyl compound biosynthetic process	IEP	Enrichment
BP	GO:1902679	negative regulation of RNA biosynthetic process	IEP	Enrichment
BP	GO:1903507	negative regulation of nucleic acid-templated transcription	IEP	Enrichment
BP	GO:2000113	negative regulation of cellular macromolecule biosynthetic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR006115	6PGDH_NADP-bd	5	173
IPR006114	6PGDH_C	178	467

External Links

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AKI49373 (gnd, L2625_01473)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation