AKI49554 (hemA, L2625_01662)

Aliases : hemA, L2625_01662

Description : glutamyl-tRNA reductase [Ensembl]. Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase, Tetrapyrrole biosynthesis [Interproscan].

Gene families : OG_02_0000915 (OrthoFinder) Phylogenetic Tree(s): OG0000915_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AKI49554
Cluster	HCCA: Cluster_20

Target	Alias	Description	ECC score	Gene Family Method	Actions
CCP43246	hemA, Rv0509	Probable glutamyl-tRNA reductase HemA (GLUTR) [Ensembl]....	0.04	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005488	binding	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008883	glutamyl-tRNA reductase activity	IEA	Interproscan
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016491	oxidoreductase activity	None	Extended
MF	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	None	Extended
MF	GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	None	Extended
BP	GO:0018130	heterocycle biosynthetic process	None	Extended
BP	GO:0019438	aromatic compound biosynthetic process	None	Extended
BP	GO:0033013	tetrapyrrole metabolic process	None	Extended
BP	GO:0033014	tetrapyrrole biosynthetic process	IEA	Interproscan
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044271	cellular nitrogen compound biosynthetic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
MF	GO:0050661	NADP binding	IEA	Interproscan
BP	GO:0055114	obsolete oxidation-reduction process	IEA	Interproscan
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0140098	catalytic activity, acting on RNA	None	Extended
MF	GO:0140101	catalytic activity, acting on a tRNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901362	organic cyclic compound biosynthetic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003848	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity	IEP	Enrichment
MF	GO:0004325	ferrochelatase activity	IEP	Enrichment
MF	GO:0004357	glutamate-cysteine ligase activity	IEP	Enrichment
MF	GO:0004418	hydroxymethylbilane synthase activity	IEP	Enrichment
MF	GO:0004421	hydroxymethylglutaryl-CoA synthase activity	IEP	Enrichment
MF	GO:0004655	porphobilinogen synthase activity	IEP	Enrichment
MF	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	IEP	Enrichment
MF	GO:0004751	ribose-5-phosphate isomerase activity	IEP	Enrichment
MF	GO:0004853	uroporphyrinogen decarboxylase activity	IEP	Enrichment
BP	GO:0006270	DNA replication initiation	IEP	Enrichment
BP	GO:0006275	regulation of DNA replication	IEP	Enrichment
BP	GO:0006575	cellular modified amino acid metabolic process	IEP	Enrichment
BP	GO:0006749	glutathione metabolic process	IEP	Enrichment
BP	GO:0006750	glutathione biosynthetic process	IEP	Enrichment
BP	GO:0006778	porphyrin-containing compound metabolic process	IEP	Enrichment
BP	GO:0006779	porphyrin-containing compound biosynthetic process	IEP	Enrichment
BP	GO:0006783	heme biosynthetic process	IEP	Enrichment
BP	GO:0006784	heme A biosynthetic process	IEP	Enrichment
MF	GO:0008762	UDP-N-acetylmuramate dehydrogenase activity	IEP	Enrichment
BP	GO:0009052	pentose-phosphate shunt, non-oxidative branch	IEP	Enrichment
MF	GO:0016301	kinase activity	IEP	Enrichment
MF	GO:0016740	transferase activity	IEP	Enrichment
MF	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	IEP	Enrichment
MF	GO:0016829	lyase activity	IEP	Enrichment
MF	GO:0016835	carbon-oxygen lyase activity	IEP	Enrichment
MF	GO:0016836	hydro-lyase activity	IEP	Enrichment
BP	GO:0019184	nonribosomal peptide biosynthetic process	IEP	Enrichment
BP	GO:0042168	heme metabolic process	IEP	Enrichment
BP	GO:0042398	cellular modified amino acid biosynthetic process	IEP	Enrichment
BP	GO:0042440	pigment metabolic process	IEP	Enrichment
BP	GO:0046148	pigment biosynthetic process	IEP	Enrichment
BP	GO:0046160	heme a metabolic process	IEP	Enrichment
MF	GO:0061731	ribonucleoside-diphosphate reductase activity	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR006151	Shikm_DH/Glu-tRNA_Rdtase	171	304
IPR015896	4pyrrol_synth_GluRdtase_dimer	321	418
IPR015895	4pyrrol_synth_GluRdtase_N	7	156

External Links

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AKI49554 (hemA, L2625_01662)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation