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AKI49671 (menD, L2625_01786)


Aliases : menD, L2625_01786

Description : 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase [Ensembl]. Menaquinone biosynthesis protein MenD, Thiamine pyrophosphate enzyme [Interproscan].


Gene families : OG_02_0001378 (OrthoFinder) Phylogenetic Tree(s): OG0001378_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: AKI49671
Cluster HCCA: Cluster_20

Target Alias Description ECC score Gene Family Method Actions
AAL21210 STM2309, menD 2-oxoglutarate decarboxylase [Ensembl]. Thiamine... 0.03 OrthoFinder
CPC41822 menD, ERS093114_00380 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carbox... 0.03 OrthoFinder
KNA59356 VCV51_031330 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carbox... 0.03 OrthoFinder

Type GO Term Name Evidence Source
MF GO:0003824 catalytic activity IEA Interproscan
MF GO:0030976 thiamine pyrophosphate binding IEA Interproscan
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Type GO Term Name Evidence Source
MF GO:0000166 nucleotide binding IEP Enrichment
MF GO:0003848 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity IEP Enrichment
MF GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity IEP Enrichment
MF GO:0004325 ferrochelatase activity IEP Enrichment
MF GO:0004329 formate-tetrahydrofolate ligase activity IEP Enrichment
MF GO:0004357 glutamate-cysteine ligase activity IEP Enrichment
MF GO:0004418 hydroxymethylbilane synthase activity IEP Enrichment
MF GO:0004420 hydroxymethylglutaryl-CoA reductase (NADPH) activity IEP Enrichment
MF GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity IEP Enrichment
MF GO:0004655 porphobilinogen synthase activity IEP Enrichment
MF GO:0004817 cysteine-tRNA ligase activity IEP Enrichment
MF GO:0004853 uroporphyrinogen decarboxylase activity IEP Enrichment
MF GO:0005524 ATP binding IEP Enrichment
BP GO:0006098 pentose-phosphate shunt IEP Enrichment
BP GO:0006289 nucleotide-excision repair IEP Enrichment
BP GO:0006423 cysteinyl-tRNA aminoacylation IEP Enrichment
BP GO:0006575 cellular modified amino acid metabolic process IEP Enrichment
BP GO:0006725 cellular aromatic compound metabolic process IEP Enrichment
BP GO:0006739 NADP metabolic process IEP Enrichment
BP GO:0006740 NADPH regeneration IEP Enrichment
BP GO:0006749 glutathione metabolic process IEP Enrichment
BP GO:0006750 glutathione biosynthetic process IEP Enrichment
BP GO:0006778 porphyrin-containing compound metabolic process IEP Enrichment
BP GO:0006779 porphyrin-containing compound biosynthetic process IEP Enrichment
BP GO:0006807 nitrogen compound metabolic process IEP Enrichment
BP GO:0008152 metabolic process IEP Enrichment
MF GO:0008661 1-deoxy-D-xylulose-5-phosphate synthase activity IEP Enrichment
MF GO:0008883 glutamyl-tRNA reductase activity IEP Enrichment
MF GO:0008897 holo-[acyl-carrier-protein] synthase activity IEP Enrichment
BP GO:0009987 cellular process IEP Enrichment
MF GO:0016491 oxidoreductase activity IEP Enrichment
MF GO:0016744 transketolase or transaldolase activity IEP Enrichment
MF GO:0016879 ligase activity, forming carbon-nitrogen bonds IEP Enrichment
MF GO:0017076 purine nucleotide binding IEP Enrichment
BP GO:0018130 heterocycle biosynthetic process IEP Enrichment
BP GO:0019184 nonribosomal peptide biosynthetic process IEP Enrichment
BP GO:0019438 aromatic compound biosynthetic process IEP Enrichment
BP GO:0019725 cellular homeostasis IEP Enrichment
MF GO:0030554 adenyl nucleotide binding IEP Enrichment
MF GO:0032553 ribonucleotide binding IEP Enrichment
MF GO:0032555 purine ribonucleotide binding IEP Enrichment
MF GO:0032559 adenyl ribonucleotide binding IEP Enrichment
BP GO:0033013 tetrapyrrole metabolic process IEP Enrichment
BP GO:0033014 tetrapyrrole biosynthetic process IEP Enrichment
BP GO:0034641 cellular nitrogen compound metabolic process IEP Enrichment
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Enrichment
BP GO:0042398 cellular modified amino acid biosynthetic process IEP Enrichment
BP GO:0042592 homeostatic process IEP Enrichment
BP GO:0044237 cellular metabolic process IEP Enrichment
BP GO:0044249 cellular biosynthetic process IEP Enrichment
BP GO:0044271 cellular nitrogen compound biosynthetic process IEP Enrichment
BP GO:0045454 cell redox homeostasis IEP Enrichment
BP GO:0046483 heterocycle metabolic process IEP Enrichment
MF GO:0050661 NADP binding IEP Enrichment
BP GO:0051156 glucose 6-phosphate metabolic process IEP Enrichment
BP GO:0065008 regulation of biological quality IEP Enrichment
BP GO:0071704 organic substance metabolic process IEP Enrichment
MF GO:0097367 carbohydrate derivative binding IEP Enrichment
MF GO:1901265 nucleoside phosphate binding IEP Enrichment
BP GO:1901360 organic cyclic compound metabolic process IEP Enrichment
BP GO:1901362 organic cyclic compound biosynthetic process IEP Enrichment
BP GO:1901566 organonitrogen compound biosynthetic process IEP Enrichment
BP GO:1901576 organic substance biosynthetic process IEP Enrichment
InterPro domains Description Start Stop
IPR032264 MenD_middle 205 405
IPR012001 Thiamin_PyroP_enz_TPP-bd_dom 13 184
IPR011766 TPP_enzyme-bd_C 438 554
No external refs found!