AAL18966 (STM0002, thrA)

Aliases : STM0002, thrA

Description : aspartokinase I [Ensembl]. ACT domain, Homoserine dehydrogenase, Amino acid kinase family [Interproscan].

Gene families : OG_02_0000145 (OrthoFinder) Phylogenetic Tree(s): OG0000145_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AAL18966
Cluster	HCCA: Cluster_39

Target	Alias	Description	ECC score	Gene Family Method
AAC73113	thrA, b0002	Bifunctional aspartokinase/homoserine dehydrogenase 1...	0.3	OrthoFinder
AAC76922	metL, b3940	Bifunctional aspartokinase/homoserine dehydrogenase 2...	0.18	OrthoFinder
AAC76994	lysC, b4024	lysine-sensitive aspartokinase 3 [Ensembl]. ACT domain,...	0.14	OrthoFinder
AAK99178	spr0374, lysC	Aspartate kinase [Ensembl]. ACT domain, Amino acid...	0.03	OrthoFinder
AGT26473	N559_4889	aspartate kinase III [Ensembl]. Amino acid kinase family...	0.17	OrthoFinder
AHY39819	CJ8421_02840	aspartate kinase [Ensembl]. ACT domain, Amino acid...	0.02	OrthoFinder
AKI50307	L2625_02494	aspartate kinase [Ensembl]. CASTOR,...	0.08	OrthoFinder
CPC31970	lysC, ERS093114_00024	Aspartokinase [Ensembl]. Amino acid kinase family [Interproscan].	0.03	OrthoFinder
CPC33474	lysC2, ERS093114_00089	aspartate kinase [Ensembl]. Amino acid kinase family...	0.04	OrthoFinder
EDJ90402	thrA, CGSHi22421_01632	bifunctional aspartokinase I/homeserine dehydrogenase I...	0.05	OrthoFinder
KNA50221	VCV51_030256	aspartate kinase [Ensembl]. Amino acid kinase family...	0.15	OrthoFinder
KNA53043	VCV51_033356	aspartate kinase [Ensembl]. ACT domain, Amino acid...	0.2	OrthoFinder
KNA54894	VCV51_031799	homoserine dehydrogenase [Ensembl]. Amino acid kinase...	0.19	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005488	binding	None	Extended
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006520	cellular amino acid metabolic process	IEA	Interproscan
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016491	oxidoreductase activity	IEA	Interproscan
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
MF	GO:0050661	NADP binding	IEA	Interproscan
BP	GO:0055114	obsolete oxidation-reduction process	IEA	Interproscan
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000096	sulfur amino acid metabolic process	IEP	Enrichment
BP	GO:0000097	sulfur amino acid biosynthetic process	IEP	Enrichment
MF	GO:0003852	2-isopropylmalate synthase activity	IEP	Enrichment
MF	GO:0003871	5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity	IEP	Enrichment
MF	GO:0004107	chorismate synthase activity	IEP	Enrichment
MF	GO:0004478	methionine adenosyltransferase activity	IEP	Enrichment
MF	GO:0005524	ATP binding	IEP	Enrichment
BP	GO:0006536	glutamate metabolic process	IEP	Enrichment
BP	GO:0006537	glutamate biosynthetic process	IEP	Enrichment
BP	GO:0006551	leucine metabolic process	IEP	Enrichment
BP	GO:0006553	lysine metabolic process	IEP	Enrichment
BP	GO:0006555	methionine metabolic process	IEP	Enrichment
BP	GO:0006556	S-adenosylmethionine biosynthetic process	IEP	Enrichment
BP	GO:0006772	thiamine metabolic process	IEP	Enrichment
BP	GO:0006790	sulfur compound metabolic process	IEP	Enrichment
BP	GO:0006810	transport	IEP	Enrichment
MF	GO:0008172	S-methyltransferase activity	IEP	Enrichment
BP	GO:0008652	cellular amino acid biosynthetic process	IEP	Enrichment
MF	GO:0008705	methionine synthase activity	IEP	Enrichment
MF	GO:0008839	4-hydroxy-tetrahydrodipicolinate reductase	IEP	Enrichment
BP	GO:0009058	biosynthetic process	IEP	Enrichment
BP	GO:0009066	aspartate family amino acid metabolic process	IEP	Enrichment
BP	GO:0009067	aspartate family amino acid biosynthetic process	IEP	Enrichment
BP	GO:0009084	glutamine family amino acid biosynthetic process	IEP	Enrichment
BP	GO:0009085	lysine biosynthetic process	IEP	Enrichment
BP	GO:0009086	methionine biosynthetic process	IEP	Enrichment
BP	GO:0009089	lysine biosynthetic process via diaminopimelate	IEP	Enrichment
BP	GO:0009098	leucine biosynthetic process	IEP	Enrichment
BP	GO:0009228	thiamine biosynthetic process	IEP	Enrichment
BP	GO:0015833	peptide transport	IEP	Enrichment
MF	GO:0015930	glutamate synthase activity	IEP	Enrichment
CC	GO:0016020	membrane	IEP	Enrichment
BP	GO:0016053	organic acid biosynthetic process	IEP	Enrichment
MF	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	IEP	Enrichment
MF	GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	IEP	Enrichment
MF	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	IEP	Enrichment
MF	GO:0016838	carbon-oxygen lyase activity, acting on phosphates	IEP	Enrichment
MF	GO:0016887	ATPase	IEP	Enrichment
MF	GO:0017076	purine nucleotide binding	IEP	Enrichment
MF	GO:0019842	vitamin binding	IEP	Enrichment
MF	GO:0030554	adenyl nucleotide binding	IEP	Enrichment
MF	GO:0031419	cobalamin binding	IEP	Enrichment
MF	GO:0032553	ribonucleotide binding	IEP	Enrichment
MF	GO:0032555	purine ribonucleotide binding	IEP	Enrichment
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Enrichment
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Enrichment
MF	GO:0042084	5-methyltetrahydrofolate-dependent methyltransferase activity	IEP	Enrichment
MF	GO:0042085	5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity	IEP	Enrichment
BP	GO:0042723	thiamine-containing compound metabolic process	IEP	Enrichment
BP	GO:0042724	thiamine-containing compound biosynthetic process	IEP	Enrichment
BP	GO:0042886	amide transport	IEP	Enrichment
MF	GO:0043167	ion binding	IEP	Enrichment
MF	GO:0043168	anion binding	IEP	Enrichment
BP	GO:0043648	dicarboxylic acid metabolic process	IEP	Enrichment
BP	GO:0043650	dicarboxylic acid biosynthetic process	IEP	Enrichment
BP	GO:0044249	cellular biosynthetic process	IEP	Enrichment
BP	GO:0044272	sulfur compound biosynthetic process	IEP	Enrichment
BP	GO:0044283	small molecule biosynthetic process	IEP	Enrichment
BP	GO:0046394	carboxylic acid biosynthetic process	IEP	Enrichment
BP	GO:0046451	diaminopimelate metabolic process	IEP	Enrichment
BP	GO:0046500	S-adenosylmethionine metabolic process	IEP	Enrichment
MF	GO:0046906	tetrapyrrole binding	IEP	Enrichment
BP	GO:0051179	localization	IEP	Enrichment
BP	GO:0051234	establishment of localization	IEP	Enrichment
MF	GO:0051536	iron-sulfur cluster binding	IEP	Enrichment
MF	GO:0051540	metal cluster binding	IEP	Enrichment
BP	GO:0055085	transmembrane transport	IEP	Enrichment
MF	GO:0097367	carbohydrate derivative binding	IEP	Enrichment
BP	GO:1901566	organonitrogen compound biosynthetic process	IEP	Enrichment
BP	GO:1901576	organic substance biosynthetic process	IEP	Enrichment
BP	GO:1901605	alpha-amino acid metabolic process	IEP	Enrichment
BP	GO:1901607	alpha-amino acid biosynthetic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR001048	Asp/Glu/Uridylate_kinase	2	284
IPR027795	CASTOR_ACT_dom	314	375
IPR027795	CASTOR_ACT_dom	393	453
IPR005106	Asp/hSer_DH_NAD-bd	472	605
IPR001342	HDH_cat	614	811

External Links

No external refs found!

AAL18966 (STM0002, thrA)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation