Coexpression cluster: Cluster_39 (HCCA)

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Average Expression Profile

Enriched GO Terms (corrected p-value < 0.05) (download table)
ID Label % in cluster Enrichment log2 p-value Corrected p-value
GO:0006520 cellular amino acid metabolic process 18.6% (8/43) 3.58 0.0 3.2e-05
GO:0000096 sulfur amino acid metabolic process 9.3% (4/43) 5.73 0.0 3.4e-05
GO:0006790 sulfur compound metabolic process 11.63% (5/43) 4.73 1e-06 4e-05
GO:0043436 oxoacid metabolic process 18.6% (8/43) 3.16 2e-06 6.2e-05
GO:0019752 carboxylic acid metabolic process 18.6% (8/43) 3.16 2e-06 6.2e-05
GO:0006082 organic acid metabolic process 18.6% (8/43) 3.07 3e-06 7e-05
GO:1901605 alpha-amino acid metabolic process 11.63% (5/43) 4.35 3e-06 8.1e-05
GO:0036094 small molecule binding 30.23% (13/43) 2.07 5e-06 9.8e-05
GO:0019842 vitamin binding 11.63% (5/43) 3.96 1.3e-05 0.000216
GO:0070279 vitamin B6 binding 9.3% (4/43) 4.2 5.4e-05 0.000706
GO:0030170 pyridoxal phosphate binding 9.3% (4/43) 4.2 5.4e-05 0.000706
GO:0043167 ion binding 27.91% (12/43) 1.72 0.000161 0.001949
GO:0043168 anion binding 23.26% (10/43) 1.87 0.000274 0.002481
GO:0050667 homocysteine metabolic process 4.65% (2/43) 6.14 0.00026 0.002511
GO:0019346 transsulfuration 4.65% (2/43) 6.14 0.00026 0.002511
GO:0009092 homoserine metabolic process 4.65% (2/43) 6.14 0.00026 0.002511
GO:0044281 small molecule metabolic process 18.6% (8/43) 2.17 0.000304 0.002592
GO:0055114 obsolete oxidation-reduction process 18.6% (8/43) 2.16 0.000327 0.002632
GO:0006534 cysteine metabolic process 4.65% (2/43) 5.73 0.000516 0.003744
GO:0006555 methionine metabolic process 4.65% (2/43) 5.73 0.000516 0.003744
GO:0016491 oxidoreductase activity 18.6% (8/43) 2.03 0.000602 0.004157
GO:0009069 serine family amino acid metabolic process 4.65% (2/43) 5.4 0.000855 0.005638
GO:0008652 cellular amino acid biosynthetic process 6.98% (3/43) 3.79 0.001218 0.007677
GO:0042886 amide transport 4.65% (2/43) 4.92 0.001775 0.009899
GO:0015833 peptide transport 4.65% (2/43) 4.92 0.001775 0.009899
GO:0044272 sulfur compound biosynthetic process 4.65% (2/43) 4.92 0.001775 0.009899
GO:0046394 carboxylic acid biosynthetic process 6.98% (3/43) 3.5 0.00218 0.011705
GO:0097159 organic cyclic compound binding 30.23% (13/43) 1.19 0.002839 0.014197
GO:1901363 heterocyclic compound binding 30.23% (13/43) 1.19 0.002839 0.014197
GO:0009066 aspartate family amino acid metabolic process 4.65% (2/43) 4.56 0.003006 0.014531
GO:1901564 organonitrogen compound metabolic process 18.6% (8/43) 1.6 0.003969 0.014756
GO:1901265 nucleoside phosphate binding 18.6% (8/43) 1.6 0.003969 0.014756
GO:0000166 nucleotide binding 18.6% (8/43) 1.6 0.003969 0.014756
GO:0055085 transmembrane transport 18.6% (8/43) 1.64 0.003317 0.015029
GO:0016053 organic acid biosynthetic process 6.98% (3/43) 3.31 0.003215 0.015036
GO:0006810 transport 23.26% (10/43) 1.37 0.003912 0.015757
GO:0051234 establishment of localization 23.26% (10/43) 1.37 0.003912 0.015757
GO:0051179 localization 23.26% (10/43) 1.37 0.003912 0.015757
GO:0050661 NADP binding 4.65% (2/43) 4.4 0.003736 0.016414
GO:0005488 binding 34.88% (15/43) 0.98 0.004971 0.018018
GO:0009987 cellular process 39.53% (17/43) 0.86 0.006191 0.021896
GO:1901607 alpha-amino acid biosynthetic process 4.65% (2/43) 4.03 0.00636 0.021956
GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity 2.33% (1/43) 6.73 0.009442 0.025354
GO:0015930 glutamate synthase activity 2.33% (1/43) 6.73 0.009442 0.025354
GO:0004478 methionine adenosyltransferase activity 2.33% (1/43) 6.73 0.009442 0.025354
GO:0006556 S-adenosylmethionine biosynthetic process 2.33% (1/43) 6.73 0.009442 0.025354
GO:0006537 glutamate biosynthetic process 2.33% (1/43) 6.73 0.009442 0.025354
GO:0042085 5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity 2.33% (1/43) 6.73 0.009442 0.025354
GO:0043650 dicarboxylic acid biosynthetic process 2.33% (1/43) 6.73 0.009442 0.025354
GO:0006536 glutamate metabolic process 2.33% (1/43) 6.73 0.009442 0.025354
GO:0003852 2-isopropylmalate synthase activity 2.33% (1/43) 6.73 0.009442 0.025354
GO:0003871 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity 2.33% (1/43) 6.73 0.009442 0.025354
GO:0046500 S-adenosylmethionine metabolic process 2.33% (1/43) 6.73 0.009442 0.025354
GO:0003674 molecular_function 60.47% (26/43) 0.55 0.008744 0.029485
GO:0008150 biological_process 51.16% (22/43) 0.6 0.01286 0.033904
GO:0009086 methionine biosynthetic process 2.33% (1/43) 5.73 0.018797 0.043962
GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 2.33% (1/43) 5.73 0.018797 0.043962
GO:0009084 glutamine family amino acid biosynthetic process 2.33% (1/43) 5.73 0.018797 0.043962
GO:0009098 leucine biosynthetic process 2.33% (1/43) 5.73 0.018797 0.043962
GO:0006551 leucine metabolic process 2.33% (1/43) 5.73 0.018797 0.043962
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 4.65% (2/43) 3.27 0.017849 0.045407
GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 4.65% (2/43) 3.27 0.017849 0.045407
Enriched Clades (corrected p-value < 0.05) (download table)
Clade % in cluster Enrichment log2 p-value Corrected p-value Gene Family Method
No enriched Clades found
Similar Clusters (download table)
Species Clustering Method Target Jaccard index Gene Family Method (for comparison) Actions
Campylobacter jejuni HCCA Cluster_2 0.035 OrthoFinder Compare
Campylobacter jejuni HCCA Cluster_11 0.086 OrthoFinder Compare
Clostridioides difficile HCCA Cluster_20 0.065 OrthoFinder Compare
Clostridioides difficile HCCA Cluster_27 0.057 OrthoFinder Compare
Clostridioides difficile HCCA Cluster_40 0.033 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_21 0.034 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_26 0.068 OrthoFinder Compare
Escherichia coli HCCA Cluster_2 0.053 OrthoFinder Compare
Escherichia coli HCCA Cluster_7 0.056 OrthoFinder Compare
Escherichia coli HCCA Cluster_11 0.155 OrthoFinder Compare
Escherichia coli HCCA Cluster_28 0.048 OrthoFinder Compare
Escherichia coli HCCA Cluster_30 0.049 OrthoFinder Compare
Escherichia coli HCCA Cluster_31 0.039 OrthoFinder Compare
Escherichia coli HCCA Cluster_37 0.101 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_3 0.047 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_8 0.083 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_9 0.034 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_13 0.034 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_15 0.051 OrthoFinder Compare
Helicobacter pylori HCCA Cluster_8 0.031 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_1 0.029 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_2 0.036 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_9 0.076 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_11 0.162 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_22 0.05 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_32 0.037 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_37 0.03 OrthoFinder Compare
Listeria monocytogenes HCCA Cluster_6 0.106 OrthoFinder Compare
Listeria monocytogenes HCCA Cluster_18 0.031 OrthoFinder Compare
Listeria monocytogenes HCCA Cluster_29 0.036 OrthoFinder Compare
Mycobacterium tuberculosis HCCA Cluster_38 0.028 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_12 0.032 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_14 0.033 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_19 0.029 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_23 0.039 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_33 0.027 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_38 0.046 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_39 0.032 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_48 0.043 OrthoFinder Compare
Salmonella enterica HCCA Cluster_7 0.036 OrthoFinder Compare
Salmonella enterica HCCA Cluster_8 0.029 OrthoFinder Compare
Salmonella enterica HCCA Cluster_10 0.033 OrthoFinder Compare
Salmonella enterica HCCA Cluster_15 0.071 OrthoFinder Compare
Salmonella enterica HCCA Cluster_38 0.027 OrthoFinder Compare
Staphylococcus aureus HCCA Cluster_1 0.154 OrthoFinder Compare
Staphylococcus aureus HCCA Cluster_6 0.042 OrthoFinder Compare
Staphylococcus aureus HCCA Cluster_16 0.038 OrthoFinder Compare
Staphylococcus aureus HCCA Cluster_25 0.056 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_8 0.027 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_19 0.042 OrthoFinder Compare
Streptococcus pyogenes HCAA Cluster_10 0.047 OrthoFinder Compare
Streptococcus pyogenes HCAA Cluster_17 0.031 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_2 0.062 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_16 0.033 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_25 0.075 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_28 0.076 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_37 0.048 OrthoFinder Compare
Sequences (43) (download table)

InterPro Domains

GO Terms

Family Terms