AAL20632 (STM1714, topA)

Aliases : STM1714, topA

Description : DNA topoisomerase type I, omega protein [Ensembl]. Toprim domain, DNA topoisomerase, Topoisomerase I zinc-ribbon-like, Topoisomerase DNA binding C4 zinc finger [Interproscan].

Gene families : OG_02_0000393 (OrthoFinder) Phylogenetic Tree(s): OG0000393_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AAL20632
Cluster	HCCA: Cluster_3

Target	Alias	Description	ECC score	Gene Family Method
AAK99944	spr1141, topA	DNA topoisomerase I [Ensembl]. Toprim domain, DNA...	0.02	OrthoFinder
ADK86690	topA, MPNE_0293	DNA topoisomerase I [Ensembl]. Toprim domain [Interproscan].	0.02	OrthoFinder
AKP15097	topA, WX61_01039	DNA topoisomerase 1 [Ensembl]. Toprim domain, DNA...	0.02	OrthoFinder
CCG27509	No alias	DNA topoisomerase I [Ensembl]. Toprim domain, DNA...	0.08	OrthoFinder
CCL17440	topA, BN171_1500016	DNA topoisomerase I [Ensembl]. DNA topoisomerase, Toprim...	0.02	OrthoFinder
CPC35500	topA, ERS093114_00174	DNA topoisomerase I [Ensembl]. Toprim domain, DNA...	0.02	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003916	DNA topoisomerase activity	IEA	Interproscan
MF	GO:0003917	DNA topoisomerase type I (single strand cut, ATP-independent) activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005694	chromosome	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006265	DNA topological change	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006996	organelle organization	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
MF	GO:0016853	isomerase activity	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043228	non-membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043232	intracellular non-membrane-bounded organelle	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0051276	chromosome organization	None	Extended
BP	GO:0071103	DNA conformation change	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
CC	GO:0110165	cellular anatomical entity	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003723	RNA binding	IEP	Enrichment
MF	GO:0003735	structural constituent of ribosome	IEP	Enrichment
MF	GO:0003918	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity	IEP	Enrichment
MF	GO:0004312	fatty acid synthase activity	IEP	Enrichment
MF	GO:0004315	3-oxoacyl-[acyl-carrier-protein] synthase activity	IEP	Enrichment
MF	GO:0004518	nuclease activity	IEP	Enrichment
MF	GO:0005198	structural molecule activity	IEP	Enrichment
MF	GO:0005315	inorganic phosphate transmembrane transporter activity	IEP	Enrichment
MF	GO:0005524	ATP binding	IEP	Enrichment
CC	GO:0005840	ribosome	IEP	Enrichment
BP	GO:0006396	RNA processing	IEP	Enrichment
BP	GO:0006399	tRNA metabolic process	IEP	Enrichment
BP	GO:0006412	translation	IEP	Enrichment
BP	GO:0006518	peptide metabolic process	IEP	Enrichment
BP	GO:0006633	fatty acid biosynthetic process	IEP	Enrichment
BP	GO:0006817	phosphate ion transport	IEP	Enrichment
BP	GO:0008033	tRNA processing	IEP	Enrichment
MF	GO:0008408	3'-5' exonuclease activity	IEP	Enrichment
BP	GO:0009058	biosynthetic process	IEP	Enrichment
BP	GO:0009059	macromolecule biosynthetic process	IEP	Enrichment
BP	GO:0009451	RNA modification	IEP	Enrichment
BP	GO:0015698	inorganic anion transport	IEP	Enrichment
BP	GO:0015969	guanosine tetraphosphate metabolic process	IEP	Enrichment
BP	GO:0016070	RNA metabolic process	IEP	Enrichment
MF	GO:0016740	transferase activity	IEP	Enrichment
MF	GO:0016763	pentosyltransferase activity	IEP	Enrichment
MF	GO:0017150	tRNA dihydrouridine synthase activity	IEP	Enrichment
MF	GO:0019843	rRNA binding	IEP	Enrichment
MF	GO:0030554	adenyl nucleotide binding	IEP	Enrichment
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Enrichment
BP	GO:0033865	nucleoside bisphosphate metabolic process	IEP	Enrichment
BP	GO:0033875	ribonucleoside bisphosphate metabolic process	IEP	Enrichment
BP	GO:0034032	purine nucleoside bisphosphate metabolic process	IEP	Enrichment
BP	GO:0034035	purine ribonucleoside bisphosphate metabolic process	IEP	Enrichment
BP	GO:0034470	ncRNA processing	IEP	Enrichment
BP	GO:0034645	cellular macromolecule biosynthetic process	IEP	Enrichment
BP	GO:0034660	ncRNA metabolic process	IEP	Enrichment
MF	GO:0035596	methylthiotransferase activity	IEP	Enrichment
BP	GO:0043043	peptide biosynthetic process	IEP	Enrichment
BP	GO:0043603	cellular amide metabolic process	IEP	Enrichment
BP	GO:0043604	amide biosynthetic process	IEP	Enrichment
BP	GO:0044267	cellular protein metabolic process	IEP	Enrichment
MF	GO:0050497	alkylthioltransferase activity	IEP	Enrichment
BP	GO:0072330	monocarboxylic acid biosynthetic process	IEP	Enrichment
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Enrichment
BP	GO:1901576	organic substance biosynthetic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR006171	TOPRIM_domain	5	142
IPR013498	Topo_IA_Znf	597	622
IPR013498	Topo_IA_Znf	709	745
IPR013497	Topo_IA_cen	157	565
IPR013263	TopoI_Znr_bac	824	862
IPR013263	TopoI_Znr_bac	758	793

External Links

No external refs found!

AAL20632 (STM1714, topA)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation