AAL21739 (STM2859, fhlA)

Aliases : STM2859, fhlA

Description : formate hydrogen-lyase transcriptional activator for fdhF, hyc and hyp operons [Ensembl]. GAF domain, Sigma-54 interaction domain, Bacterial regulatory protein [Interproscan].

Gene families : OG_02_0000008 (OrthoFinder) Phylogenetic Tree(s): OG0000008_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AAL21739
Cluster	HCCA: Cluster_35

Target	Alias	Description	ECC score	Gene Family Method
AAC75773	fhlA, b2731	formate hydrogenlyase transcriptional activator...	0.09	OrthoFinder
AAC75907	ygeV, b2869	putative sigma-54-interacting transcriptional activator...	0.04	OrthoFinder
AGT22935	N559_1166, FhlA	formate hydrogenlyase transcriptional activator FhlA...	0.07	OrthoFinder
CRO39560	dctD_1	C4-dicarboxylate transport transcriptional regulatory...	0.02	OrthoFinder
CRP79684	zraR_6	Transcriptional regulatory protein ZraR [Ensembl]....	0.02	OrthoFinder
KNA50402	VCV51_031428	sigma-54 interaction domain-containing protein...	0.04	OrthoFinder
KNA55256	VCV51_033069	sigma-54 interaction domain-containing protein...	0.03	OrthoFinder
KNA59396	VCV51_031296	sigma-54 interaction domain-containing protein...	0.03	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	IEA	Interproscan
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0006355	regulation of transcription, DNA-templated	IEA	Interproscan
MF	GO:0008134	transcription factor binding	IEA	Interproscan
BP	GO:0008150	biological_process	None	Extended
BP	GO:0009889	regulation of biosynthetic process	None	Extended
BP	GO:0010468	regulation of gene expression	None	Extended
BP	GO:0010556	regulation of macromolecule biosynthetic process	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
BP	GO:0019219	regulation of nucleobase-containing compound metabolic process	None	Extended
BP	GO:0019222	regulation of metabolic process	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
BP	GO:0031323	regulation of cellular metabolic process	None	Extended
BP	GO:0031326	regulation of cellular biosynthetic process	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0043565	sequence-specific DNA binding	IEA	Interproscan
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
BP	GO:0051171	regulation of nitrogen compound metabolic process	None	Extended
BP	GO:0051252	regulation of RNA metabolic process	None	Extended
BP	GO:0060255	regulation of macromolecule metabolic process	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0080090	regulation of primary metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1903506	regulation of nucleic acid-templated transcription	None	Extended
BP	GO:2000112	regulation of cellular macromolecule biosynthetic process	None	Extended
BP	GO:2001141	regulation of RNA biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000041	transition metal ion transport	IEP	Enrichment
BP	GO:0001514	selenocysteine incorporation	IEP	Enrichment
MF	GO:0003746	translation elongation factor activity	IEP	Enrichment
MF	GO:0003824	catalytic activity	IEP	Enrichment
MF	GO:0004619	phosphoglycerate mutase activity	IEP	Enrichment
MF	GO:0004743	pyruvate kinase activity	IEP	Enrichment
MF	GO:0005525	GTP binding	IEP	Enrichment
BP	GO:0006007	glucose catabolic process	IEP	Enrichment
BP	GO:0006091	generation of precursor metabolites and energy	IEP	Enrichment
BP	GO:0006417	regulation of translation	IEP	Enrichment
BP	GO:0006451	translational readthrough	IEP	Enrichment
BP	GO:0006508	proteolysis	IEP	Enrichment
BP	GO:0006612	protein targeting to membrane	IEP	Enrichment
BP	GO:0006613	cotranslational protein targeting to membrane	IEP	Enrichment
BP	GO:0006614	SRP-dependent cotranslational protein targeting to membrane	IEP	Enrichment
BP	GO:0006721	terpenoid metabolic process	IEP	Enrichment
BP	GO:0006826	iron ion transport	IEP	Enrichment
MF	GO:0008233	peptidase activity	IEP	Enrichment
MF	GO:0008312	7S RNA binding	IEP	Enrichment
MF	GO:0008998	ribonucleoside-triphosphate reductase activity	IEP	Enrichment
BP	GO:0009056	catabolic process	IEP	Enrichment
BP	GO:0010608	posttranscriptional regulation of gene expression	IEP	Enrichment
MF	GO:0015232	heme transmembrane transporter activity	IEP	Enrichment
BP	GO:0015886	heme transport	IEP	Enrichment
BP	GO:0016052	carbohydrate catabolic process	IEP	Enrichment
BP	GO:0016114	terpenoid biosynthetic process	IEP	Enrichment
MF	GO:0016151	nickel cation binding	IEP	Enrichment
MF	GO:0016491	oxidoreductase activity	IEP	Enrichment
MF	GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	IEP	Enrichment
MF	GO:0016728	oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor	IEP	Enrichment
BP	GO:0017004	cytochrome complex assembly	IEP	Enrichment
MF	GO:0019001	guanyl nucleotide binding	IEP	Enrichment
BP	GO:0019320	hexose catabolic process	IEP	Enrichment
BP	GO:0019538	protein metabolic process	IEP	Enrichment
BP	GO:0019645	anaerobic electron transport chain	IEP	Enrichment
BP	GO:0022900	electron transport chain	IEP	Enrichment
BP	GO:0022904	respiratory electron transport chain	IEP	Enrichment
MF	GO:0030955	potassium ion binding	IEP	Enrichment
MF	GO:0031420	alkali metal ion binding	IEP	Enrichment
BP	GO:0032268	regulation of cellular protein metabolic process	IEP	Enrichment
MF	GO:0032561	guanyl ribonucleotide binding	IEP	Enrichment
BP	GO:0033365	protein localization to organelle	IEP	Enrichment
BP	GO:0034248	regulation of cellular amide metabolic process	IEP	Enrichment
BP	GO:0034613	cellular protein localization	IEP	Enrichment
BP	GO:0034622	cellular protein-containing complex assembly	IEP	Enrichment
MF	GO:0043169	cation binding	IEP	Enrichment
BP	GO:0043170	macromolecule metabolic process	IEP	Enrichment
MF	GO:0043546	molybdopterin cofactor binding	IEP	Enrichment
BP	GO:0043933	protein-containing complex subunit organization	IEP	Enrichment
BP	GO:0045047	protein targeting to ER	IEP	Enrichment
BP	GO:0046365	monosaccharide catabolic process	IEP	Enrichment
MF	GO:0046429	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity	IEP	Enrichment
MF	GO:0046872	metal ion binding	IEP	Enrichment
MF	GO:0046914	transition metal ion binding	IEP	Enrichment
CC	GO:0048500	signal recognition particle	IEP	Enrichment
BP	GO:0051246	regulation of protein metabolic process	IEP	Enrichment
BP	GO:0051668	localization within membrane	IEP	Enrichment
MF	GO:0052592	oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor	IEP	Enrichment
BP	GO:0055114	obsolete oxidation-reduction process	IEP	Enrichment
BP	GO:0065003	protein-containing complex assembly	IEP	Enrichment
BP	GO:0070727	cellular macromolecule localization	IEP	Enrichment
BP	GO:0070972	protein localization to endoplasmic reticulum	IEP	Enrichment
BP	GO:0072594	establishment of protein localization to organelle	IEP	Enrichment
BP	GO:0072599	establishment of protein localization to endoplasmic reticulum	IEP	Enrichment
BP	GO:0072657	protein localization to membrane	IEP	Enrichment
BP	GO:0090150	establishment of protein localization to membrane	IEP	Enrichment
BP	GO:1901575	organic substance catabolic process	IEP	Enrichment
BP	GO:1901678	iron coordination entity transport	IEP	Enrichment
CC	GO:1990904	ribonucleoprotein complex	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR002078	Sigma_54_int	381	548
IPR003018	GAF	202	344
IPR002197	HTH_Fis	645	684

External Links

No external refs found!

AAL21739 (STM2859, fhlA)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation