CPC69467 (mnmE, ERS093114_01080)

Aliases : mnmE, ERS093114_01080

Description : tRNA (5-carboxymethylaminomethyl-2-thiouridylate) synthase [Ensembl]. MnmE helical domain, 50S ribosome-binding GTPase, GTP-binding protein TrmE N-terminus [Interproscan].

Gene families : OG_02_0000630 (OrthoFinder) Phylogenetic Tree(s): OG0000630_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: CPC69467
Cluster	HCCA: Cluster_5

Target	Alias	Description	ECC score	Gene Family Method
AEA95244	trmE, OG1RF_12557	tRNA modification GTPase TrmE [Ensembl]. MnmE helical...	0.03	OrthoFinder
AHY40170	trmE, CJ8421_04735	tRNA modification GTPase TrmE [Ensembl]. MnmE helical...	0.04	OrthoFinder
CCG27668	TrmE	GTPase and tRNA-U34 5-formylation enzyme TrmE [Ensembl]....	0.03	OrthoFinder
CRP70196	mnmE	tRNA modification GTPase MnmE [Ensembl]. MnmE helical...	0.04	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005525	GTP binding	IEA	Interproscan
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0019001	guanyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032561	guanyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003678	DNA helicase activity	IEP	Enrichment
MF	GO:0003918	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity	IEP	Enrichment
MF	GO:0004386	helicase activity	IEP	Enrichment
MF	GO:0004652	polynucleotide adenylyltransferase activity	IEP	Enrichment
MF	GO:0004810	tRNA adenylyltransferase activity	IEP	Enrichment
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	Enrichment
BP	GO:0006259	DNA metabolic process	IEP	Enrichment
BP	GO:0006265	DNA topological change	IEP	Enrichment
BP	GO:0006281	DNA repair	IEP	Enrichment
BP	GO:0006310	DNA recombination	IEP	Enrichment
BP	GO:0006364	rRNA processing	IEP	Enrichment
BP	GO:0006396	RNA processing	IEP	Enrichment
BP	GO:0006725	cellular aromatic compound metabolic process	IEP	Enrichment
BP	GO:0006950	response to stress	IEP	Enrichment
BP	GO:0006974	cellular response to DNA damage stimulus	IEP	Enrichment
MF	GO:0008094	ATPase, acting on DNA	IEP	Enrichment
MF	GO:0008168	methyltransferase activity	IEP	Enrichment
MF	GO:0008171	O-methyltransferase activity	IEP	Enrichment
MF	GO:0008173	RNA methyltransferase activity	IEP	Enrichment
MF	GO:0008175	tRNA methyltransferase activity	IEP	Enrichment
MF	GO:0008649	rRNA methyltransferase activity	IEP	Enrichment
MF	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	IEP	Enrichment
MF	GO:0009378	four-way junction helicase activity	IEP	Enrichment
CC	GO:0009379	Holliday junction helicase complex	IEP	Enrichment
MF	GO:0015103	inorganic anion transmembrane transporter activity	IEP	Enrichment
MF	GO:0015105	arsenite transmembrane transporter activity	IEP	Enrichment
BP	GO:0015698	inorganic anion transport	IEP	Enrichment
BP	GO:0015700	arsenite transport	IEP	Enrichment
BP	GO:0016072	rRNA metabolic process	IEP	Enrichment
MF	GO:0016426	tRNA (adenine) methyltransferase activity	IEP	Enrichment
MF	GO:0016429	tRNA (adenine-N1-)-methyltransferase activity	IEP	Enrichment
MF	GO:0016741	transferase activity, transferring one-carbon groups	IEP	Enrichment
MF	GO:0016887	ATPase	IEP	Enrichment
CC	GO:0033202	DNA helicase complex	IEP	Enrichment
BP	GO:0033554	cellular response to stress	IEP	Enrichment
BP	GO:0034470	ncRNA processing	IEP	Enrichment
BP	GO:0034660	ncRNA metabolic process	IEP	Enrichment
BP	GO:0043170	macromolecule metabolic process	IEP	Enrichment
BP	GO:0046483	heterocycle metabolic process	IEP	Enrichment
BP	GO:0050896	response to stimulus	IEP	Enrichment
BP	GO:0051716	cellular response to stimulus	IEP	Enrichment
MF	GO:0070566	adenylyltransferase activity	IEP	Enrichment
BP	GO:0090304	nucleic acid metabolic process	IEP	Enrichment
MF	GO:0140097	catalytic activity, acting on DNA	IEP	Enrichment
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Enrichment
MF	GO:0140102	catalytic activity, acting on a rRNA	IEP	Enrichment
BP	GO:1901360	organic cyclic compound metabolic process	IEP	Enrichment
CC	GO:1904949	ATPase complex	IEP	Enrichment
MF	GO:1990817	RNA adenylyltransferase activity	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR025867	MnmE_helical	127	456
IPR018948	GTP-bd_TrmE_N	5	124
IPR006073	GTP-bd	225	336

External Links

No external refs found!

CPC69467 (mnmE, ERS093114_01080)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation