AAK99407 (spr0603, murD)

Aliases : spr0603, murD

Description : UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase [Ensembl]. Mur ligase family, Mur ligase middle domain [Interproscan].

Gene families : OG_02_0000439 (OrthoFinder) Phylogenetic Tree(s): OG0000439_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AAK99407
Cluster	HCCA: Cluster_3

Target	Alias	Description	ECC score	Gene Family Method
AGT25951	N559_4338	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase...	0.03	OrthoFinder
AKI50031	murD, L2625_02186	UDP-N-acetylmuramoylalanine-D-glutamate ligase...	0.06	OrthoFinder
KNA53285	VCV51_031616	UDP-N-acetylmuramoylalanine-D-glutamate ligase...	0.03	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	IEA	Interproscan
MF	GO:0016874	ligase activity	IEA	Interproscan
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003848	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity	IEP	Enrichment
MF	GO:0003924	GTPase activity	IEP	Enrichment
MF	GO:0004127	cytidylate kinase activity	IEP	Enrichment
MF	GO:0004150	dihydroneopterin aldolase activity	IEP	Enrichment
MF	GO:0004347	glucose-6-phosphate isomerase activity	IEP	Enrichment
MF	GO:0004421	hydroxymethylglutaryl-CoA synthase activity	IEP	Enrichment
MF	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	IEP	Enrichment
MF	GO:0004618	phosphoglycerate kinase activity	IEP	Enrichment
MF	GO:0004743	pyruvate kinase activity	IEP	Enrichment
MF	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	IEP	Enrichment
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEP	Enrichment
BP	GO:0006082	organic acid metabolic process	IEP	Enrichment
BP	GO:0006090	pyruvate metabolic process	IEP	Enrichment
BP	GO:0006091	generation of precursor metabolites and energy	IEP	Enrichment
BP	GO:0006096	glycolytic process	IEP	Enrichment
BP	GO:0006098	pentose-phosphate shunt	IEP	Enrichment
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	Enrichment
BP	GO:0006165	nucleoside diphosphate phosphorylation	IEP	Enrichment
BP	GO:0006399	tRNA metabolic process	IEP	Enrichment
BP	GO:0006418	tRNA aminoacylation for protein translation	IEP	Enrichment
BP	GO:0006720	isoprenoid metabolic process	IEP	Enrichment
BP	GO:0006725	cellular aromatic compound metabolic process	IEP	Enrichment
BP	GO:0006739	NADP metabolic process	IEP	Enrichment
BP	GO:0006740	NADPH regeneration	IEP	Enrichment
BP	GO:0006757	ATP generation from ADP	IEP	Enrichment
MF	GO:0008270	zinc ion binding	IEP	Enrichment
BP	GO:0008299	isoprenoid biosynthetic process	IEP	Enrichment
BP	GO:0008610	lipid biosynthetic process	IEP	Enrichment
MF	GO:0008762	UDP-N-acetylmuramate dehydrogenase activity	IEP	Enrichment
MF	GO:0008998	ribonucleoside-triphosphate reductase activity	IEP	Enrichment
BP	GO:0009132	nucleoside diphosphate metabolic process	IEP	Enrichment
BP	GO:0009135	purine nucleoside diphosphate metabolic process	IEP	Enrichment
BP	GO:0009179	purine ribonucleoside diphosphate metabolic process	IEP	Enrichment
BP	GO:0009185	ribonucleoside diphosphate metabolic process	IEP	Enrichment
BP	GO:0009987	cellular process	IEP	Enrichment
BP	GO:0016052	carbohydrate catabolic process	IEP	Enrichment
MF	GO:0016462	pyrophosphatase activity	IEP	Enrichment
MF	GO:0016491	oxidoreductase activity	IEP	Enrichment
MF	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	IEP	Enrichment
MF	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEP	Enrichment
MF	GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	IEP	Enrichment
MF	GO:0016728	oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor	IEP	Enrichment
MF	GO:0016774	phosphotransferase activity, carboxyl group as acceptor	IEP	Enrichment
MF	GO:0016776	phosphotransferase activity, phosphate group as acceptor	IEP	Enrichment
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Enrichment
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Enrichment
MF	GO:0016832	aldehyde-lyase activity	IEP	Enrichment
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	IEP	Enrichment
MF	GO:0017111	nucleoside-triphosphatase activity	IEP	Enrichment
BP	GO:0019725	cellular homeostasis	IEP	Enrichment
BP	GO:0019752	carboxylic acid metabolic process	IEP	Enrichment
BP	GO:0032787	monocarboxylic acid metabolic process	IEP	Enrichment
BP	GO:0034660	ncRNA metabolic process	IEP	Enrichment
BP	GO:0042592	homeostatic process	IEP	Enrichment
BP	GO:0043038	amino acid activation	IEP	Enrichment
BP	GO:0043039	tRNA aminoacylation	IEP	Enrichment
BP	GO:0043170	macromolecule metabolic process	IEP	Enrichment
BP	GO:0043436	oxoacid metabolic process	IEP	Enrichment
BP	GO:0044237	cellular metabolic process	IEP	Enrichment
BP	GO:0044238	primary metabolic process	IEP	Enrichment
BP	GO:0044255	cellular lipid metabolic process	IEP	Enrichment
BP	GO:0044281	small molecule metabolic process	IEP	Enrichment
BP	GO:0045454	cell redox homeostasis	IEP	Enrichment
BP	GO:0046031	ADP metabolic process	IEP	Enrichment
BP	GO:0046034	ATP metabolic process	IEP	Enrichment
BP	GO:0046483	heterocycle metabolic process	IEP	Enrichment
BP	GO:0046939	nucleotide phosphorylation	IEP	Enrichment
MF	GO:0050145	nucleoside monophosphate kinase activity	IEP	Enrichment
BP	GO:0051156	glucose 6-phosphate metabolic process	IEP	Enrichment
BP	GO:0055114	obsolete oxidation-reduction process	IEP	Enrichment
MF	GO:0061731	ribonucleoside-diphosphate reductase activity	IEP	Enrichment
BP	GO:0065008	regulation of biological quality	IEP	Enrichment
BP	GO:0071704	organic substance metabolic process	IEP	Enrichment
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Enrichment
MF	GO:0140101	catalytic activity, acting on a tRNA	IEP	Enrichment
BP	GO:1901360	organic cyclic compound metabolic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR004101	Mur_ligase_C	310	378
IPR013221	Mur_ligase_cen	117	290

External Links

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AAK99407 (spr0603, murD)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation