CCP45646 (proS, Rv2845c)

Aliases : proS, Rv2845c

Description : Probable prolyl-tRNA synthetase ProS (proline--tRNA ligase) (PRORS) (global RNA synthesis factor) (proline translase) [Ensembl]. Anticodon binding domain, Aminoacyl-tRNA editing domain, tRNA synthetase class II core domain (G [Interproscan].

Gene families : OG_02_0000443 (OrthoFinder) Phylogenetic Tree(s): OG0000443_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: CCP45646
Cluster	HCCA: Cluster_23

Target	Alias	Description	ECC score	Gene Family Method	Actions
AKI49315	proS, L2625_01409	prolyl-tRNA synthetase [Ensembl]. Aminoacyl-tRNA...	0.02	OrthoFinder
AKP14223	proS, WX61_00134	Proline--tRNA ligase [Ensembl]. Anticodon binding...	0.03	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEA	Interproscan
MF	GO:0002161	aminoacyl-tRNA editing activity	IEA	Interproscan
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006399	tRNA metabolic process	None	Extended
BP	GO:0006418	tRNA aminoacylation for protein translation	IEA	Interproscan
BP	GO:0006520	cellular amino acid metabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016788	hydrolase activity, acting on ester bonds	None	Extended
MF	GO:0016874	ligase activity	None	Extended
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034660	ncRNA metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0043038	amino acid activation	None	Extended
BP	GO:0043039	tRNA aminoacylation	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
MF	GO:0052689	carboxylic ester hydrolase activity	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140098	catalytic activity, acting on RNA	None	Extended
MF	GO:0140101	catalytic activity, acting on a tRNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000270	peptidoglycan metabolic process	IEP	Enrichment
MF	GO:0004806	triglyceride lipase activity	IEP	Enrichment
BP	GO:0006022	aminoglycan metabolic process	IEP	Enrichment
BP	GO:0006026	aminoglycan catabolic process	IEP	Enrichment
BP	GO:0006027	glycosaminoglycan catabolic process	IEP	Enrichment
BP	GO:0006400	tRNA modification	IEP	Enrichment
MF	GO:0008144	drug binding	IEP	Enrichment
MF	GO:0008168	methyltransferase activity	IEP	Enrichment
MF	GO:0008173	RNA methyltransferase activity	IEP	Enrichment
MF	GO:0008175	tRNA methyltransferase activity	IEP	Enrichment
MF	GO:0008176	tRNA (guanine-N7-)-methyltransferase activity	IEP	Enrichment
MF	GO:0008658	penicillin binding	IEP	Enrichment
MF	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity	IEP	Enrichment
MF	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	IEP	Enrichment
BP	GO:0009056	catabolic process	IEP	Enrichment
BP	GO:0009253	peptidoglycan catabolic process	IEP	Enrichment
BP	GO:0009451	RNA modification	IEP	Enrichment
BP	GO:0016042	lipid catabolic process	IEP	Enrichment
MF	GO:0016298	lipase activity	IEP	Enrichment
MF	GO:0016423	tRNA (guanine) methyltransferase activity	IEP	Enrichment
MF	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	IEP	Enrichment
BP	GO:0030203	glycosaminoglycan metabolic process	IEP	Enrichment
MF	GO:0031406	carboxylic acid binding	IEP	Enrichment
MF	GO:0033218	amide binding	IEP	Enrichment
MF	GO:0033293	monocarboxylic acid binding	IEP	Enrichment
BP	GO:0034654	nucleobase-containing compound biosynthetic process	IEP	Enrichment
MF	GO:0061783	peptidoglycan muralytic activity	IEP	Enrichment
BP	GO:1901136	carbohydrate derivative catabolic process	IEP	Enrichment
BP	GO:1901575	organic substance catabolic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR007214	YbaK/aa-tRNA-synth-assoc-dom	257	387
IPR004154	Anticodon-bd	487	561
IPR002314	aa-tRNA-synt_IIb	92	467

External Links

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CCP45646 (proS, Rv2845c)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation