CCP46279 (rpoA, Rv3457c)

Aliases : rpoA, Rv3457c

Description : Probable DNA-directed RNA polymerase (alpha chain) RpoA (transcriptase alpha chain) (RNA polymerase alpha subunit) (DNA-directed RNA nucleotidyltransferase) [Ensembl]. Bacterial RNA polymerase, RNA polymerase Rpb3/RpoA insert domain, RNA polymerase Rpb3/Rpb11 dimerisation domain [Interproscan].

Gene families : OG_02_0000391 (OrthoFinder) Phylogenetic Tree(s): OG0000391_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: CCP46279
Cluster	HCCA: Cluster_25

Target	Alias	Description	ECC score	Gene Family Method
AAC76320	rpoA, b3295	RNA polymerase, alpha subunit [Ensembl]. Bacterial RNA...	0.23	OrthoFinder
AAK99019	spr0215, rpoA	RNA polymerase alpha subunit [Ensembl]. Bacterial RNA...	0.17	OrthoFinder
AAL22278	STM3415, rpoA	RNA polymerase, alpha subunit [Ensembl]. Bacterial RNA...	0.26	OrthoFinder
ADK86748	rpoA, MPNE_0220	DNA-directed RNA polymerase, alpha subunit [Ensembl]....	0.1	OrthoFinder
AEA92864	rpoA, OG1RF_10177	DNA-directed RNA polymerase subunit alpha [Ensembl]....	0.12	OrthoFinder
AGT22265	N559_0457	DNA-directed RNA polymerase subunit alpha [Ensembl]. RNA...	0.12	OrthoFinder
AHY40768	CJ8421_07980	DNA-directed RNA polymerase subunit alpha [Ensembl]....	0.12	OrthoFinder
AKI50541	rpoA, L2625_02751	DNA-directed RNA polymerase, alpha subunit [Ensembl]....	0.15	OrthoFinder
AKP15146	rpoA, WX61_01092	DNA-directed RNA polymerase subunit alpha [Ensembl]....	0.08	OrthoFinder
CBI65743	rpoA, HPB8_186	DNA-directed RNA polymerase subunit alpha [Ensembl]....	0.1	OrthoFinder
CCG27405	No alias	DNA-directed RNA polymerase alpha subunit [Ensembl]....	0.07	OrthoFinder
CCL20591	rpoA, BN171_70031	DNA-directed RNA polymerase subunit alpha [Ensembl]. RNA...	0.15	OrthoFinder
CPD14384	rpoA, ERS093114_02148	DNA-directed RNA polymerase alpha subunit [Ensembl]....	0.21	OrthoFinder
CRO74499	rpoA	DNA-directed RNA polymerase subunit alpha [Ensembl]....	0.19	OrthoFinder
EDJ91381	CGSHi22421_04738	DNA-directed RNA polymerase subunit alpha [Ensembl]....	0.22	OrthoFinder
KNA54997	VCV51_033180	DNA-directed RNA polymerase [Ensembl]. Bacterial RNA...	0.15	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003899	DNA-directed 5'-3' RNA polymerase activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006351	transcription, DNA-templated	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009059	macromolecule biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	None	Extended
MF	GO:0016779	nucleotidyltransferase activity	None	Extended
BP	GO:0018130	heterocycle biosynthetic process	None	Extended
BP	GO:0019438	aromatic compound biosynthetic process	None	Extended
BP	GO:0032774	RNA biosynthetic process	None	Extended
MF	GO:0034062	5'-3' RNA polymerase activity	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034645	cellular macromolecule biosynthetic process	None	Extended
BP	GO:0034654	nucleobase-containing compound biosynthetic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044271	cellular nitrogen compound biosynthetic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
MF	GO:0046983	protein dimerization activity	IEA	Interproscan
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
BP	GO:0097659	nucleic acid-templated transcription	None	Extended
MF	GO:0097747	RNA polymerase activity	None	Extended
MF	GO:0140098	catalytic activity, acting on RNA	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901362	organic cyclic compound biosynthetic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000096	sulfur amino acid metabolic process	IEP	Enrichment
MF	GO:0003723	RNA binding	IEP	Enrichment
MF	GO:0003735	structural constituent of ribosome	IEP	Enrichment
MF	GO:0003746	translation elongation factor activity	IEP	Enrichment
MF	GO:0003747	translation release factor activity	IEP	Enrichment
MF	GO:0003908	methylated-DNA-[protein]-cysteine S-methyltransferase activity	IEP	Enrichment
MF	GO:0003924	GTPase activity	IEP	Enrichment
MF	GO:0004455	ketol-acid reductoisomerase activity	IEP	Enrichment
MF	GO:0004526	ribonuclease P activity	IEP	Enrichment
MF	GO:0004549	tRNA-specific ribonuclease activity	IEP	Enrichment
MF	GO:0005198	structural molecule activity	IEP	Enrichment
MF	GO:0005525	GTP binding	IEP	Enrichment
CC	GO:0005575	cellular_component	IEP	Enrichment
CC	GO:0005840	ribosome	IEP	Enrichment
BP	GO:0006082	organic acid metabolic process	IEP	Enrichment
BP	GO:0006412	translation	IEP	Enrichment
BP	GO:0006414	translational elongation	IEP	Enrichment
BP	GO:0006415	translational termination	IEP	Enrichment
BP	GO:0006518	peptide metabolic process	IEP	Enrichment
BP	GO:0006534	cysteine metabolic process	IEP	Enrichment
BP	GO:0006633	fatty acid biosynthetic process	IEP	Enrichment
BP	GO:0006790	sulfur compound metabolic process	IEP	Enrichment
MF	GO:0008079	translation termination factor activity	IEP	Enrichment
MF	GO:0008135	translation factor activity, RNA binding	IEP	Enrichment
BP	GO:0009069	serine family amino acid metabolic process	IEP	Enrichment
BP	GO:0009081	branched-chain amino acid metabolic process	IEP	Enrichment
BP	GO:0009082	branched-chain amino acid biosynthetic process	IEP	Enrichment
BP	GO:0009092	homoserine metabolic process	IEP	Enrichment
BP	GO:0009403	toxin biosynthetic process	IEP	Enrichment
BP	GO:0009404	toxin metabolic process	IEP	Enrichment
MF	GO:0016462	pyrophosphatase activity	IEP	Enrichment
MF	GO:0016790	thiolester hydrolase activity	IEP	Enrichment
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Enrichment
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Enrichment
MF	GO:0017111	nucleoside-triphosphatase activity	IEP	Enrichment
MF	GO:0019001	guanyl nucleotide binding	IEP	Enrichment
BP	GO:0019346	transsulfuration	IEP	Enrichment
BP	GO:0019538	protein metabolic process	IEP	Enrichment
BP	GO:0019748	secondary metabolic process	IEP	Enrichment
MF	GO:0019843	rRNA binding	IEP	Enrichment
BP	GO:0022411	cellular component disassembly	IEP	Enrichment
MF	GO:0030170	pyridoxal phosphate binding	IEP	Enrichment
MF	GO:0032561	guanyl ribonucleotide binding	IEP	Enrichment
MF	GO:0032977	membrane insertase activity	IEP	Enrichment
BP	GO:0032984	protein-containing complex disassembly	IEP	Enrichment
BP	GO:0043043	peptide biosynthetic process	IEP	Enrichment
CC	GO:0043226	organelle	IEP	Enrichment
CC	GO:0043228	non-membrane-bounded organelle	IEP	Enrichment
CC	GO:0043229	intracellular organelle	IEP	Enrichment
CC	GO:0043232	intracellular non-membrane-bounded organelle	IEP	Enrichment
BP	GO:0043603	cellular amide metabolic process	IEP	Enrichment
BP	GO:0043604	amide biosynthetic process	IEP	Enrichment
BP	GO:0043624	cellular protein complex disassembly	IEP	Enrichment
BP	GO:0044267	cellular protein metabolic process	IEP	Enrichment
BP	GO:0044550	secondary metabolite biosynthetic process	IEP	Enrichment
MF	GO:0045182	translation regulator activity	IEP	Enrichment
BP	GO:0050667	homocysteine metabolic process	IEP	Enrichment
MF	GO:0070279	vitamin B6 binding	IEP	Enrichment
MF	GO:0090079	translation regulator activity, nucleic acid binding	IEP	Enrichment
CC	GO:0110165	cellular anatomical entity	IEP	Enrichment
MF	GO:0140104	molecular carrier activity	IEP	Enrichment
MF	GO:0140597	protein carrier activity	IEP	Enrichment
BP	GO:1901564	organonitrogen compound metabolic process	IEP	Enrichment
BP	GO:1901566	organonitrogen compound biosynthetic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR011262	DNA-dir_RNA_pol_insert	57	149
IPR011263	DNA-dir_RNA_pol_RpoA/D/Rpb3	24	218
IPR011260	RNAP_asu_C	241	302

External Links

No external refs found!

CCP46279 (rpoA, Rv3457c)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation