CRO12681 (mutS)

Aliases : mutS

Description : DNA mismatch repair protein MutS [Ensembl]. MutS domain V, MutS domain III, MutS family domain IV [Interproscan].

Gene families : OG_02_0000582 (OrthoFinder) Phylogenetic Tree(s): OG0000582_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: CRO12681
Cluster	HCCA: Cluster_34

Target	Alias	Description	ECC score	Gene Family Method
AAC75775	mutS, b2733	methyl-directed mismatch repair protein [Ensembl]. MutS...	0.04	OrthoFinder
AAL00690	spr1888, hexA	DNA mismatch repair protein HexA [Ensembl]. MutS domain...	0.05	OrthoFinder
AEA95122	mutS3, OG1RF_12435	DNA mismatch repair protein MutS [Ensembl]. MutS domain...	0.04	OrthoFinder
AKI49400	mutS, L2625_01500	DNA mismatch repair protein [Ensembl]. DNA mismatch...	0.03	OrthoFinder
AKP15033	mutS, WX61_00970	DNA mismatch repair protein MutS [Ensembl]. MutS domain...	0.03	OrthoFinder
EDJ90359	CGSHi22421_09935	DNA mismatch repair protein [Ensembl]. MutS domain V,...	0.04	OrthoFinder
KNA49221	VCV51_030341, MutS	DNA mismatch repair protein MutS [Ensembl]. MutS domain...	0.07	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	None	Extended
MF	GO:0003690	double-stranded DNA binding	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	None	Extended
BP	GO:0006298	mismatch repair	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0030983	mismatched DNA binding	IEA	Interproscan
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003723	RNA binding	IEP	Enrichment
MF	GO:0003747	translation release factor activity	IEP	Enrichment
MF	GO:0003824	catalytic activity	IEP	Enrichment
MF	GO:0004386	helicase activity	IEP	Enrichment
MF	GO:0004518	nuclease activity	IEP	Enrichment
MF	GO:0004527	exonuclease activity	IEP	Enrichment
MF	GO:0004751	ribose-5-phosphate isomerase activity	IEP	Enrichment
MF	GO:0004832	valine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004853	uroporphyrinogen decarboxylase activity	IEP	Enrichment
MF	GO:0005315	inorganic phosphate transmembrane transporter activity	IEP	Enrichment
CC	GO:0005737	cytoplasm	IEP	Enrichment
BP	GO:0006081	cellular aldehyde metabolic process	IEP	Enrichment
BP	GO:0006082	organic acid metabolic process	IEP	Enrichment
BP	GO:0006260	DNA replication	IEP	Enrichment
BP	GO:0006396	RNA processing	IEP	Enrichment
BP	GO:0006399	tRNA metabolic process	IEP	Enrichment
BP	GO:0006415	translational termination	IEP	Enrichment
BP	GO:0006438	valyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006520	cellular amino acid metabolic process	IEP	Enrichment
BP	GO:0006721	terpenoid metabolic process	IEP	Enrichment
BP	GO:0006779	porphyrin-containing compound biosynthetic process	IEP	Enrichment
BP	GO:0008033	tRNA processing	IEP	Enrichment
MF	GO:0008079	translation termination factor activity	IEP	Enrichment
MF	GO:0008094	ATPase, acting on DNA	IEP	Enrichment
MF	GO:0008144	drug binding	IEP	Enrichment
MF	GO:0008170	N-methyltransferase activity	IEP	Enrichment
MF	GO:0008173	RNA methyltransferase activity	IEP	Enrichment
MF	GO:0008408	3'-5' exonuclease activity	IEP	Enrichment
BP	GO:0008610	lipid biosynthetic process	IEP	Enrichment
BP	GO:0008616	queuosine biosynthetic process	IEP	Enrichment
MF	GO:0008649	rRNA methyltransferase activity	IEP	Enrichment
BP	GO:0008652	cellular amino acid biosynthetic process	IEP	Enrichment
MF	GO:0008658	penicillin binding	IEP	Enrichment
MF	GO:0008661	1-deoxy-D-xylulose-5-phosphate synthase activity	IEP	Enrichment
MF	GO:0008990	rRNA (guanine-N2-)-methyltransferase activity	IEP	Enrichment
BP	GO:0009052	pentose-phosphate shunt, non-oxidative branch	IEP	Enrichment
BP	GO:0009058	biosynthetic process	IEP	Enrichment
BP	GO:0009119	ribonucleoside metabolic process	IEP	Enrichment
BP	GO:0009163	nucleoside biosynthetic process	IEP	Enrichment
BP	GO:0009240	isopentenyl diphosphate biosynthetic process	IEP	Enrichment
BP	GO:0009451	RNA modification	IEP	Enrichment
BP	GO:0016070	RNA metabolic process	IEP	Enrichment
BP	GO:0016114	terpenoid biosynthetic process	IEP	Enrichment
MF	GO:0016435	rRNA (guanine) methyltransferase activity	IEP	Enrichment
MF	GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	IEP	Enrichment
MF	GO:0016726	oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor	IEP	Enrichment
MF	GO:0016740	transferase activity	IEP	Enrichment
MF	GO:0016744	transketolase or transaldolase activity	IEP	Enrichment
MF	GO:0016779	nucleotidyltransferase activity	IEP	Enrichment
MF	GO:0016787	hydrolase activity	IEP	Enrichment
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Enrichment
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Enrichment
MF	GO:0016853	isomerase activity	IEP	Enrichment
MF	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses	IEP	Enrichment
MF	GO:0016887	ATPase	IEP	Enrichment
MF	GO:0017150	tRNA dihydrouridine synthase activity	IEP	Enrichment
BP	GO:0019288	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway	IEP	Enrichment
BP	GO:0019682	glyceraldehyde-3-phosphate metabolic process	IEP	Enrichment
BP	GO:0019752	carboxylic acid metabolic process	IEP	Enrichment
BP	GO:0022411	cellular component disassembly	IEP	Enrichment
MF	GO:0031406	carboxylic acid binding	IEP	Enrichment
MF	GO:0032977	membrane insertase activity	IEP	Enrichment
BP	GO:0032984	protein-containing complex disassembly	IEP	Enrichment
MF	GO:0033218	amide binding	IEP	Enrichment
MF	GO:0033293	monocarboxylic acid binding	IEP	Enrichment
BP	GO:0034404	nucleobase-containing small molecule biosynthetic process	IEP	Enrichment
BP	GO:0034470	ncRNA processing	IEP	Enrichment
BP	GO:0034660	ncRNA metabolic process	IEP	Enrichment
MF	GO:0035596	methylthiotransferase activity	IEP	Enrichment
BP	GO:0042455	ribonucleoside biosynthetic process	IEP	Enrichment
MF	GO:0043177	organic acid binding	IEP	Enrichment
BP	GO:0043436	oxoacid metabolic process	IEP	Enrichment
BP	GO:0043624	cellular protein complex disassembly	IEP	Enrichment
BP	GO:0044249	cellular biosynthetic process	IEP	Enrichment
BP	GO:0044281	small molecule metabolic process	IEP	Enrichment
BP	GO:0044283	small molecule biosynthetic process	IEP	Enrichment
BP	GO:0046116	queuosine metabolic process	IEP	Enrichment
BP	GO:0046490	isopentenyl diphosphate metabolic process	IEP	Enrichment
MF	GO:0050497	alkylthioltransferase activity	IEP	Enrichment
BP	GO:0050992	dimethylallyl diphosphate biosynthetic process	IEP	Enrichment
BP	GO:0050993	dimethylallyl diphosphate metabolic process	IEP	Enrichment
MF	GO:0051745	4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity	IEP	Enrichment
MF	GO:0140097	catalytic activity, acting on DNA	IEP	Enrichment
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Enrichment
MF	GO:0140102	catalytic activity, acting on a rRNA	IEP	Enrichment
MF	GO:0140104	molecular carrier activity	IEP	Enrichment
MF	GO:0140597	protein carrier activity	IEP	Enrichment
BP	GO:1901135	carbohydrate derivative metabolic process	IEP	Enrichment
BP	GO:1901576	organic substance biosynthetic process	IEP	Enrichment
BP	GO:1901659	glycosyl compound biosynthetic process	IEP	Enrichment
MF	GO:1901681	sulfur compound binding	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR007860	DNA_mmatch_repair_MutS_con_dom	128	253
IPR007696	DNA_mismatch_repair_MutS_core	270	558
IPR007695	DNA_mismatch_repair_MutS-lik_N	8	119
IPR007861	DNA_mismatch_repair_MutS_clamp	427	517
IPR000432	DNA_mismatch_repair_MutS_C	609	795

External Links

Locus_tag	PAERUG_E11_London_26_VIM_2_06_13_01576

CRO12681 (mutS)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation