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CRP54066 (ligA)


Aliases : ligA

Description : DNA ligase [Ensembl]. Helix-hairpin-helix motif, BRCA1 C Terminus (BRCT) domain, NAD-dependent DNA ligase OB-fold domain, NAD-dependent DNA ligase adenylation domain, NAD-dependent DNA ligase C4 zinc finger domain [Interproscan].


Gene families : OG_02_0000445 (OrthoFinder) Phylogenetic Tree(s): OG0000445_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: CRP54066
Cluster HCCA: Cluster_40

Target Alias Description ECC score Gene Family Method Actions
AAK99828 spr1024, ligA DNA ligase [Ensembl]. Helix-hairpin-helix motif,... 0.03 OrthoFinder
ADK87023 ligA, MPNE_0413 DNA ligase (NAD(+)) [Ensembl]. NAD-dependent DNA ligase... 0.01 OrthoFinder
AEA93146 ligA, OG1RF_10459 NAD-dependent DNA ligase LigA [Ensembl].... 0.04 OrthoFinder
AKP15609 ligA_2, WX61_01570 DNA ligase [Ensembl]. Helix-hairpin-helix motif, BRCA1 C... 0.02 OrthoFinder
CCG26397 No alias DNA ligase [Ensembl]. Helix-hairpin-helix motif,... 0.04 OrthoFinder

Type GO Term Name Evidence Source
MF GO:0003911 DNA ligase (NAD+) activity IEA Interproscan
BP GO:0006260 DNA replication IEA Interproscan
BP GO:0006281 DNA repair IEA Interproscan
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Type GO Term Name Evidence Source
MF GO:0000166 nucleotide binding IEP Enrichment
BP GO:0000270 peptidoglycan metabolic process IEP Enrichment
MF GO:0003723 RNA binding IEP Enrichment
MF GO:0003887 DNA-directed DNA polymerase activity IEP Enrichment
MF GO:0004019 adenylosuccinate synthase activity IEP Enrichment
MF GO:0004521 endoribonuclease activity IEP Enrichment
MF GO:0004525 ribonuclease III activity IEP Enrichment
MF GO:0004540 ribonuclease activity IEP Enrichment
MF GO:0005525 GTP binding IEP Enrichment
BP GO:0006022 aminoglycan metabolic process IEP Enrichment
BP GO:0006040 amino sugar metabolic process IEP Enrichment
BP GO:0006778 porphyrin-containing compound metabolic process IEP Enrichment
BP GO:0006779 porphyrin-containing compound biosynthetic process IEP Enrichment
MF GO:0008168 methyltransferase activity IEP Enrichment
MF GO:0008716 D-alanine-D-alanine ligase activity IEP Enrichment
BP GO:0009254 peptidoglycan turnover IEP Enrichment
CC GO:0009360 DNA polymerase III complex IEP Enrichment
MF GO:0016740 transferase activity IEP Enrichment
MF GO:0016741 transferase activity, transferring one-carbon groups IEP Enrichment
MF GO:0016757 glycosyltransferase activity IEP Enrichment
MF GO:0016772 transferase activity, transferring phosphorus-containing groups IEP Enrichment
MF GO:0016879 ligase activity, forming carbon-nitrogen bonds IEP Enrichment
MF GO:0016881 acid-amino acid ligase activity IEP Enrichment
MF GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters IEP Enrichment
MF GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters IEP Enrichment
MF GO:0017076 purine nucleotide binding IEP Enrichment
MF GO:0019001 guanyl nucleotide binding IEP Enrichment
BP GO:0030203 glycosaminoglycan metabolic process IEP Enrichment
MF GO:0032296 double-stranded RNA-specific ribonuclease activity IEP Enrichment
MF GO:0032553 ribonucleotide binding IEP Enrichment
MF GO:0032555 purine ribonucleotide binding IEP Enrichment
MF GO:0032561 guanyl ribonucleotide binding IEP Enrichment
MF GO:0034061 DNA polymerase activity IEP Enrichment
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Enrichment
MF GO:0036094 small molecule binding IEP Enrichment
CC GO:0042575 DNA polymerase complex IEP Enrichment
MF GO:0043168 anion binding IEP Enrichment
CC GO:0061695 transferase complex, transferring phosphorus-containing groups IEP Enrichment
MF GO:0097159 organic cyclic compound binding IEP Enrichment
MF GO:0097367 carbohydrate derivative binding IEP Enrichment
CC GO:0140535 intracellular protein-containing complex IEP Enrichment
MF GO:1901265 nucleoside phosphate binding IEP Enrichment
MF GO:1901363 heterocyclic compound binding IEP Enrichment
CC GO:1902494 catalytic complex IEP Enrichment
CC GO:1990234 transferase complex IEP Enrichment
InterPro domains Description Start Stop
IPR004150 NAD_DNA_ligase_OB 334 410
IPR041663 DisA/LigA_HHH 534 597
IPR041663 DisA/LigA_HHH 631 687
IPR004149 Znf_DNAligase_C4 419 458
IPR001357 BRCT_dom 713 787
IPR013839 DNAligase_adenylation 7 330
Locus_tag PAERUG_E11_London_26_VIM_2_06_13_05697