AEA94915 (folC, OG1RF_12228)

Aliases : folC, OG1RF_12228

Description : tetrahydrofolate synthase [Ensembl]. Mur ligase family, Mur ligase middle domain [Interproscan].

Gene families : OG_02_0000331 (OrthoFinder) Phylogenetic Tree(s): OG0000331_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AEA94915
Cluster	HCCA: Cluster_3

Target	Alias	Description	ECC score	Gene Family Method	Actions
CCG26578	No alias	Dihydrofolate synthase / Folylpolyglutamate synthase...	0.04	OrthoFinder
CCL19735	folC, BN171_3440010	Folylpolyglutamate synthase [Ensembl]. Mur ligase...	0.03	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	IEA	Interproscan
MF	GO:0016874	ligase activity	IEA	Interproscan
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

Type	GO Term	Name	Evidence	Source
MF	GO:0004357	glutamate-cysteine ligase activity	IEP	Enrichment
BP	GO:0006091	generation of precursor metabolites and energy	IEP	Enrichment
BP	GO:0006749	glutathione metabolic process	IEP	Enrichment
BP	GO:0006750	glutathione biosynthetic process	IEP	Enrichment
MF	GO:0008097	5S rRNA binding	IEP	Enrichment
BP	GO:0009060	aerobic respiration	IEP	Enrichment
BP	GO:0015980	energy derivation by oxidation of organic compounds	IEP	Enrichment
MF	GO:0016881	acid-amino acid ligase activity	IEP	Enrichment
BP	GO:0019184	nonribosomal peptide biosynthetic process	IEP	Enrichment
BP	GO:0019646	aerobic electron transport chain	IEP	Enrichment
BP	GO:0022900	electron transport chain	IEP	Enrichment
BP	GO:0022904	respiratory electron transport chain	IEP	Enrichment
BP	GO:0043647	inositol phosphate metabolic process	IEP	Enrichment
BP	GO:0045229	external encapsulating structure organization	IEP	Enrichment
BP	GO:0045333	cellular respiration	IEP	Enrichment
BP	GO:0046164	alcohol catabolic process	IEP	Enrichment
BP	GO:0046174	polyol catabolic process	IEP	Enrichment
BP	GO:0046838	phosphorylated carbohydrate dephosphorylation	IEP	Enrichment
BP	GO:0046855	inositol phosphate dephosphorylation	IEP	Enrichment
CC	GO:0070069	cytochrome complex	IEP	Enrichment
BP	GO:0071545	inositol phosphate catabolic process	IEP	Enrichment
BP	GO:0071554	cell wall organization or biogenesis	IEP	Enrichment
BP	GO:0071555	cell wall organization	IEP	Enrichment
BP	GO:1901616	organic hydroxy compound catabolic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR013221	Mur_ligase_cen	46	273
IPR004101	Mur_ligase_C	300	373

External Links

No external refs found!