AAC74705 (nth, b1633)

Aliases : nth, b1633

Description : DNA glycosylase and apyrimidinic (AP) lyase (endonuclease III) [Ensembl]. Helix-hairpin-helix motif, Iron-sulfur binding domain of endonuclease III, HhH-GPD superfamily base excision DNA repair protein [Interproscan].

Gene families : OG_02_0000527 (OrthoFinder) Phylogenetic Tree(s): OG0000527_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AAC74705
Cluster	HCCA: Cluster_29

Target	Alias	Description	ECC score	Gene Family Method
AAL20375	STM1453, nth	endonuclease III [Ensembl]. Helix-hairpin-helix motif,...	0.09	OrthoFinder
AGT24018	N559_2317	endonuclease III [Ensembl]. Iron-sulfur binding domain...	0.11	OrthoFinder
CCP46497	nth, Rv3674c	Probable endonuclease III Nth (DNA-(apurinic or...	0.02	OrthoFinder
EDJ90330	modC, CGSHi22421_02341	molybdate transporter ATP-binding subunit [Ensembl]....	0.03	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	None	Extended
BP	GO:0006284	base-excision repair	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
MF	GO:0051536	iron-sulfur cluster binding	None	Extended
MF	GO:0051539	4 iron, 4 sulfur cluster binding	IEA	Interproscan
MF	GO:0051540	metal cluster binding	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEP	Enrichment
CC	GO:0005575	cellular_component	IEP	Enrichment
MF	GO:0010181	FMN binding	IEP	Enrichment
CC	GO:0016020	membrane	IEP	Enrichment
MF	GO:0016782	transferase activity, transferring sulphur-containing groups	IEP	Enrichment
MF	GO:0016887	ATPase	IEP	Enrichment
MF	GO:0032553	ribonucleotide binding	IEP	Enrichment
MF	GO:0035596	methylthiotransferase activity	IEP	Enrichment
MF	GO:0036094	small molecule binding	IEP	Enrichment
MF	GO:0043167	ion binding	IEP	Enrichment
MF	GO:0043168	anion binding	IEP	Enrichment
MF	GO:0050497	alkylthioltransferase activity	IEP	Enrichment
BP	GO:0051301	cell division	IEP	Enrichment
MF	GO:0097367	carbohydrate derivative binding	IEP	Enrichment
CC	GO:0110165	cellular anatomical entity	IEP	Enrichment
MF	GO:1901265	nucleoside phosphate binding	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR003265	HhH-GPD_domain	34	168
IPR000445	HhH_motif	100	127
IPR003651	Endonuclease3_FeS-loop_motif	187	203

External Links

UniProtKB	P0AB83

AAC74705 (nth, b1633)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation