Coexpression cluster: Cluster_2 (HCCA)

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Average Expression Profile

Enriched GO Terms (corrected p-value < 0.05) (download table)
ID Label % in cluster Enrichment log2 p-value Corrected p-value
GO:0003735 structural constituent of ribosome 12.22% (27/221) 3.64 0.0 0.0
GO:0005840 ribosome 11.76% (26/221) 3.66 0.0 0.0
GO:0043232 intracellular non-membrane-bounded organelle 11.76% (26/221) 3.62 0.0 0.0
GO:0043229 intracellular organelle 11.76% (26/221) 3.62 0.0 0.0
GO:0005198 structural molecule activity 12.22% (27/221) 3.56 0.0 0.0
GO:0043228 non-membrane-bounded organelle 11.76% (26/221) 3.51 0.0 0.0
GO:0043226 organelle 11.76% (26/221) 3.51 0.0 0.0
GO:0005575 cellular_component 18.1% (40/221) 1.48 0.0 0.0
GO:0110165 cellular anatomical entity 17.65% (39/221) 1.5 0.0 0.0
GO:0003723 RNA binding 6.33% (14/221) 2.51 0.0 1e-06
GO:0034641 cellular nitrogen compound metabolic process 10.86% (24/221) 1.63 0.0 1.1e-05
GO:0071704 organic substance metabolic process 16.74% (37/221) 1.23 0.0 1.2e-05
GO:0044238 primary metabolic process 14.48% (32/221) 1.27 2e-06 3.5e-05
GO:0043170 macromolecule metabolic process 10.86% (24/221) 1.53 2e-06 3.7e-05
GO:0003674 molecular_function 42.08% (93/221) 0.57 5e-06 9.8e-05
GO:0006399 tRNA metabolic process 3.62% (8/221) 2.84 5e-06 0.000102
GO:0043039 tRNA aminoacylation 3.17% (7/221) 2.99 9e-06 0.000158
GO:0043038 amino acid activation 3.17% (7/221) 2.99 9e-06 0.000158
GO:0034660 ncRNA metabolic process 3.62% (8/221) 2.7 1.3e-05 0.000172
GO:0034645 cellular macromolecule biosynthetic process 3.62% (8/221) 2.7 1.3e-05 0.000172
GO:0043043 peptide biosynthetic process 2.26% (5/221) 3.61 1.3e-05 0.000184
GO:0043604 amide biosynthetic process 2.26% (5/221) 3.61 1.3e-05 0.000184
GO:0006518 peptide metabolic process 2.26% (5/221) 3.61 1.3e-05 0.000184
GO:0008152 metabolic process 17.19% (38/221) 1.0 1.6e-05 0.000199
GO:0044260 cellular macromolecule metabolic process 5.88% (13/221) 1.96 1.7e-05 0.000203
GO:0044237 cellular metabolic process 12.22% (27/221) 1.21 2.5e-05 0.000297
GO:0043603 cellular amide metabolic process 2.26% (5/221) 3.41 3.2e-05 0.000364
GO:0006807 nitrogen compound metabolic process 11.76% (26/221) 1.21 3.7e-05 0.000408
GO:0006418 tRNA aminoacylation for protein translation 2.71% (6/221) 2.98 4.6e-05 0.000486
GO:0090304 nucleic acid metabolic process 7.24% (16/221) 1.55 7.5e-05 0.000768
GO:1901363 heterocyclic compound binding 19.46% (43/221) 0.82 0.000101 0.000963
GO:0097159 organic cyclic compound binding 19.46% (43/221) 0.82 0.000101 0.000963
GO:0046483 heterocycle metabolic process 8.6% (19/221) 1.36 0.000104 0.000966
GO:1901360 organic cyclic compound metabolic process 8.6% (19/221) 1.35 0.000116 0.001046
GO:0140098 catalytic activity, acting on RNA 4.07% (9/221) 2.13 0.000129 0.001125
GO:1901564 organonitrogen compound metabolic process 7.69% (17/221) 1.42 0.000142 0.001207
GO:0016874 ligase activity 4.07% (9/221) 2.09 0.000163 0.001278
GO:0006139 nucleobase-containing compound metabolic process 7.69% (17/221) 1.41 0.00016 0.001285
GO:0006412 translation 1.81% (4/221) 3.51 0.000157 0.001301
GO:0003746 translation elongation factor activity 1.36% (3/221) 4.09 0.000199 0.001523
GO:0006725 cellular aromatic compound metabolic process 8.14% (18/221) 1.33 0.000212 0.001579
GO:0016875 ligase activity, forming carbon-oxygen bonds 3.17% (7/221) 2.38 0.000237 0.001685
GO:0004812 aminoacyl-tRNA ligase activity 3.17% (7/221) 2.38 0.000237 0.001685
GO:0005488 binding 20.81% (46/221) 0.72 0.000297 0.002068
GO:0090079 translation regulator activity, nucleic acid binding 1.81% (4/221) 3.28 0.00035 0.002232
GO:0008135 translation factor activity, RNA binding 1.81% (4/221) 3.28 0.00035 0.002232
GO:0045182 translation regulator activity 1.81% (4/221) 3.28 0.00035 0.002232
GO:0044267 cellular protein metabolic process 1.81% (4/221) 3.28 0.00035 0.002232
GO:0003676 nucleic acid binding 10.86% (24/221) 1.06 0.000371 0.00227
GO:0016070 RNA metabolic process 4.98% (11/221) 1.72 0.000368 0.002301
GO:0140101 catalytic activity, acting on a tRNA 3.17% (7/221) 2.2 0.000546 0.003276
GO:0016779 nucleotidyltransferase activity 1.81% (4/221) 2.92 0.001147 0.006753
GO:1901576 organic substance biosynthetic process 6.33% (14/221) 1.28 0.001489 0.008436
GO:0044271 cellular nitrogen compound biosynthetic process 4.52% (10/221) 1.58 0.00148 0.008542
GO:0006974 cellular response to DNA damage stimulus 2.26% (5/221) 2.33 0.002292 0.012523
GO:0006281 DNA repair 2.26% (5/221) 2.33 0.002292 0.012523
GO:0009059 macromolecule biosynthetic process 3.62% (8/221) 1.7 0.002562 0.013755
GO:0018580 nitronate monooxygenase activity 0.9% (2/221) 4.09 0.003424 0.01455
GO:0004497 monooxygenase activity 0.9% (2/221) 4.09 0.003424 0.01455
GO:0016703 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) 0.9% (2/221) 4.09 0.003424 0.01455
GO:0004826 phenylalanine-tRNA ligase activity 0.9% (2/221) 4.09 0.003424 0.01455
GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 0.9% (2/221) 4.09 0.003424 0.01455
GO:0097659 nucleic acid-templated transcription 0.9% (2/221) 4.09 0.003424 0.01455
GO:0006351 transcription, DNA-templated 0.9% (2/221) 4.09 0.003424 0.01455
GO:0019843 rRNA binding 0.9% (2/221) 4.09 0.003424 0.01455
GO:0009378 four-way junction helicase activity 0.9% (2/221) 4.09 0.003424 0.01455
GO:0017076 purine nucleotide binding 9.95% (22/221) 0.89 0.00309 0.015502
GO:0035639 purine ribonucleoside triphosphate binding 9.95% (22/221) 0.89 0.00309 0.015502
GO:0032555 purine ribonucleotide binding 9.95% (22/221) 0.89 0.00309 0.015502
GO:0032553 ribonucleotide binding 9.95% (22/221) 0.86 0.003942 0.015666
GO:0051716 cellular response to stimulus 2.26% (5/221) 2.17 0.003911 0.015747
GO:0033554 cellular response to stress 2.26% (5/221) 2.17 0.003911 0.015747
GO:0006950 response to stress 2.26% (5/221) 2.17 0.003911 0.015747
GO:0016853 isomerase activity 2.26% (5/221) 2.17 0.003911 0.015747
GO:0140097 catalytic activity, acting on DNA 2.71% (6/221) 1.98 0.003243 0.01575
GO:0044249 cellular biosynthetic process 5.88% (13/221) 1.22 0.00323 0.015939
GO:0003824 catalytic activity 20.36% (45/221) 0.57 0.003029 0.015982
GO:0009987 cellular process 13.12% (29/221) 0.71 0.004997 0.019602
GO:0019752 carboxylic acid metabolic process 3.62% (8/221) 1.54 0.0053 0.019779
GO:1901566 organonitrogen compound biosynthetic process 3.62% (8/221) 1.54 0.0053 0.019779
GO:0043436 oxoacid metabolic process 3.62% (8/221) 1.54 0.0053 0.019779
GO:0005975 carbohydrate metabolic process 3.62% (8/221) 1.54 0.0053 0.019779
GO:0003924 GTPase activity 1.36% (3/221) 2.87 0.005837 0.021521
GO:0006082 organic acid metabolic process 3.62% (8/221) 1.51 0.006047 0.022029
GO:0043168 anion binding 9.95% (22/221) 0.79 0.007351 0.026463
GO:0006520 cellular amino acid metabolic process 3.17% (7/221) 1.58 0.007674 0.026991
GO:0050896 response to stimulus 2.26% (5/221) 1.95 0.007669 0.027289
GO:0044281 small molecule metabolic process 4.98% (11/221) 1.18 0.008378 0.029132
GO:0097367 carbohydrate derivative binding 9.95% (22/221) 0.76 0.009075 0.031203
GO:0000049 tRNA binding 0.9% (2/221) 3.51 0.009873 0.033198
GO:0036094 small molecule binding 10.41% (23/221) 0.73 0.009867 0.033548
GO:0009058 biosynthetic process 6.79% (15/221) 0.93 0.010876 0.036174
GO:0019538 protein metabolic process 2.71% (6/221) 1.63 0.011066 0.036409
GO:0000166 nucleotide binding 9.95% (22/221) 0.73 0.011681 0.037624
GO:1901265 nucleoside phosphate binding 9.95% (22/221) 0.73 0.011681 0.037624
GO:0016462 pyrophosphatase activity 1.36% (3/221) 2.51 0.012835 0.040489
GO:0017111 nucleoside-triphosphatase activity 1.36% (3/221) 2.51 0.012835 0.040489
GO:0030554 adenyl nucleotide binding 8.6% (19/221) 0.76 0.015842 0.048475
GO:0032559 adenyl ribonucleotide binding 8.6% (19/221) 0.76 0.015842 0.048475
GO:0005524 ATP binding 8.6% (19/221) 0.76 0.015842 0.048475
Enriched Clades (corrected p-value < 0.05) (download table)
Clade % in cluster Enrichment log2 p-value Corrected p-value Gene Family Method
No enriched Clades found
Similar Clusters (download table)
Species Clustering Method Target Jaccard index Gene Family Method (for comparison) Actions
Campylobacter jejuni HCCA Cluster_2 0.049 OrthoFinder Compare
Campylobacter jejuni HCCA Cluster_8 0.129 OrthoFinder Compare
Campylobacter jejuni HCCA Cluster_14 0.03 OrthoFinder Compare
Clostridioides difficile HCCA Cluster_8 0.028 OrthoFinder Compare
Clostridioides difficile HCCA Cluster_24 0.031 OrthoFinder Compare
Clostridioides difficile HCCA Cluster_27 0.033 OrthoFinder Compare
Clostridioides difficile HCCA Cluster_28 0.033 OrthoFinder Compare
Clostridioides difficile HCCA Cluster_38 0.03 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_1 0.038 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_7 0.111 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_12 0.063 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_13 0.029 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_15 0.029 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_18 0.045 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_21 0.035 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_28 0.027 OrthoFinder Compare
Escherichia coli HCCA Cluster_1 0.151 OrthoFinder Compare
Escherichia coli HCCA Cluster_11 0.029 OrthoFinder Compare
Escherichia coli HCCA Cluster_28 0.037 OrthoFinder Compare
Escherichia coli HCCA Cluster_37 0.032 OrthoFinder Compare
Escherichia coli HCCA Cluster_39 0.029 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_3 0.029 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_8 0.032 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_11 0.028 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_17 0.118 OrthoFinder Compare
Helicobacter pylori HCCA Cluster_9 0.128 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_2 0.033 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_11 0.032 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_12 0.098 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_29 0.029 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_34 0.034 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_38 0.027 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_44 0.03 OrthoFinder Compare
Listeria monocytogenes HCCA Cluster_2 0.121 OrthoFinder Compare
Listeria monocytogenes HCCA Cluster_4 0.04 OrthoFinder Compare
Listeria monocytogenes HCCA Cluster_7 0.03 OrthoFinder Compare
Listeria monocytogenes HCCA Cluster_8 0.042 OrthoFinder Compare
Listeria monocytogenes HCCA Cluster_17 0.034 OrthoFinder Compare
Listeria monocytogenes HCCA Cluster_18 0.076 OrthoFinder Compare
Listeria monocytogenes HCCA Cluster_20 0.036 OrthoFinder Compare
Listeria monocytogenes HCCA Cluster_24 0.057 OrthoFinder Compare
Listeria monocytogenes HCCA Cluster_26 0.027 OrthoFinder Compare
Mycoplasma pneumoniae HCAA Cluster_1 0.041 OrthoFinder Compare
Mycoplasma pneumoniae HCAA Cluster_3 0.051 OrthoFinder Compare
Mycoplasma pneumoniae HCAA Cluster_5 0.08 OrthoFinder Compare
Mycobacterium tuberculosis HCCA Cluster_6 0.032 OrthoFinder Compare
Mycobacterium tuberculosis HCCA Cluster_25 0.092 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_1 0.029 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_5 0.049 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_6 0.077 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_7 0.028 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_12 0.046 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_17 0.036 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_22 0.091 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_35 0.033 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_47 0.03 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_51 0.042 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_62 0.039 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_63 0.036 OrthoFinder Compare
Salmonella enterica HCCA Cluster_3 0.027 OrthoFinder Compare
Salmonella enterica HCCA Cluster_23 0.162 OrthoFinder Compare
Salmonella enterica HCCA Cluster_31 0.031 OrthoFinder Compare
Salmonella enterica HCCA Cluster_44 0.027 OrthoFinder Compare
Staphylococcus aureus HCCA Cluster_5 0.051 OrthoFinder Compare
Staphylococcus aureus HCCA Cluster_14 0.034 OrthoFinder Compare
Staphylococcus aureus HCCA Cluster_19 0.053 OrthoFinder Compare
Staphylococcus aureus HCCA Cluster_24 0.156 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_1 0.027 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_2 0.031 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_3 0.035 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_7 0.082 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_10 0.03 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_13 0.113 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_14 0.043 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_18 0.048 OrthoFinder Compare
Streptococcus pyogenes HCAA Cluster_1 0.037 OrthoFinder Compare
Streptococcus pyogenes HCAA Cluster_4 0.109 OrthoFinder Compare
Streptococcus pyogenes HCAA Cluster_5 0.032 OrthoFinder Compare
Streptococcus pyogenes HCAA Cluster_7 0.053 OrthoFinder Compare
Streptococcus pyogenes HCAA Cluster_9 0.039 OrthoFinder Compare
Streptococcus pyogenes HCAA Cluster_11 0.068 OrthoFinder Compare
Streptococcus pyogenes HCAA Cluster_12 0.032 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_1 0.032 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_8 0.143 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_11 0.04 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_24 0.07 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_29 0.031 OrthoFinder Compare
Sequences (221) (download table)

InterPro Domains

GO Terms

Family Terms