CBI65827 (purD, HPB8_270)

Aliases : purD, HPB8_270

Description : phosphoribosylamine-glycine ligase [Ensembl]. Phosphoribosylglycinamide synthetase [Interproscan].

Gene families : OG_02_0000644 (OrthoFinder) Phylogenetic Tree(s): OG0000644_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: CBI65827
Cluster	HCCA: Cluster_14

Target	Alias	Description	ECC score	Gene Family Method	Actions
AAL23003	STM4175, purD	phosphoribosylglycinamide synthetase [Ensembl]....	0.02	OrthoFinder
CRO51514	purD	Phosphoribosylamine--glycine ligase [Ensembl]....	0.02	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004637	phosphoribosylamine-glycine ligase activity	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006144	purine nucleobase metabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009112	nucleobase metabolic process	None	Extended
BP	GO:0009113	purine nucleobase biosynthetic process	IEA	Interproscan
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016874	ligase activity	None	Extended
MF	GO:0016879	ligase activity, forming carbon-nitrogen bonds	None	Extended
BP	GO:0018130	heterocycle biosynthetic process	None	Extended
BP	GO:0019438	aromatic compound biosynthetic process	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0042440	pigment metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044271	cellular nitrogen compound biosynthetic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0046112	nucleobase biosynthetic process	None	Extended
BP	GO:0046148	pigment biosynthetic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0055086	nucleobase-containing small molecule metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0072521	purine-containing compound metabolic process	None	Extended
BP	GO:0072522	purine-containing compound biosynthetic process	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901362	organic cyclic compound biosynthetic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEP	Enrichment
MF	GO:0002161	aminoacyl-tRNA editing activity	IEP	Enrichment
MF	GO:0003989	acetyl-CoA carboxylase activity	IEP	Enrichment
MF	GO:0004619	phosphoglycerate mutase activity	IEP	Enrichment
MF	GO:0004749	ribose phosphate diphosphokinase activity	IEP	Enrichment
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEP	Enrichment
MF	GO:0005488	binding	IEP	Enrichment
MF	GO:0005524	ATP binding	IEP	Enrichment
BP	GO:0006007	glucose catabolic process	IEP	Enrichment
BP	GO:0006082	organic acid metabolic process	IEP	Enrichment
BP	GO:0006220	pyrimidine nucleotide metabolic process	IEP	Enrichment
BP	GO:0006221	pyrimidine nucleotide biosynthetic process	IEP	Enrichment
BP	GO:0006231	dTMP biosynthetic process	IEP	Enrichment
BP	GO:0006399	tRNA metabolic process	IEP	Enrichment
BP	GO:0006418	tRNA aminoacylation for protein translation	IEP	Enrichment
BP	GO:0006520	cellular amino acid metabolic process	IEP	Enrichment
BP	GO:0006885	regulation of pH	IEP	Enrichment
MF	GO:0008883	glutamyl-tRNA reductase activity	IEP	Enrichment
BP	GO:0009123	nucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009124	nucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009129	pyrimidine nucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009130	pyrimidine nucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009157	deoxyribonucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009162	deoxyribonucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009176	pyrimidine deoxyribonucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009177	pyrimidine deoxyribonucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009219	pyrimidine deoxyribonucleotide metabolic process	IEP	Enrichment
BP	GO:0009221	pyrimidine deoxyribonucleotide biosynthetic process	IEP	Enrichment
BP	GO:0009262	deoxyribonucleotide metabolic process	IEP	Enrichment
BP	GO:0009263	deoxyribonucleotide biosynthetic process	IEP	Enrichment
BP	GO:0009265	2'-deoxyribonucleotide biosynthetic process	IEP	Enrichment
BP	GO:0009394	2'-deoxyribonucleotide metabolic process	IEP	Enrichment
BP	GO:0016043	cellular component organization	IEP	Enrichment
BP	GO:0016070	RNA metabolic process	IEP	Enrichment
MF	GO:0016421	CoA carboxylase activity	IEP	Enrichment
MF	GO:0016853	isomerase activity	IEP	Enrichment
MF	GO:0016866	intramolecular transferase activity	IEP	Enrichment
MF	GO:0016868	intramolecular transferase activity, phosphotransferases	IEP	Enrichment
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	IEP	Enrichment
MF	GO:0016885	ligase activity, forming carbon-carbon bonds	IEP	Enrichment
MF	GO:0017076	purine nucleotide binding	IEP	Enrichment
BP	GO:0019320	hexose catabolic process	IEP	Enrichment
BP	GO:0019692	deoxyribose phosphate metabolic process	IEP	Enrichment
BP	GO:0019752	carboxylic acid metabolic process	IEP	Enrichment
MF	GO:0030145	manganese ion binding	IEP	Enrichment
MF	GO:0030554	adenyl nucleotide binding	IEP	Enrichment
MF	GO:0032553	ribonucleotide binding	IEP	Enrichment
MF	GO:0032555	purine ribonucleotide binding	IEP	Enrichment
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Enrichment
BP	GO:0034660	ncRNA metabolic process	IEP	Enrichment
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Enrichment
MF	GO:0036094	small molecule binding	IEP	Enrichment
BP	GO:0043038	amino acid activation	IEP	Enrichment
BP	GO:0043039	tRNA aminoacylation	IEP	Enrichment
MF	GO:0043167	ion binding	IEP	Enrichment
MF	GO:0043168	anion binding	IEP	Enrichment
CC	GO:0043190	ATP-binding cassette (ABC) transporter complex	IEP	Enrichment
BP	GO:0043436	oxoacid metabolic process	IEP	Enrichment
BP	GO:0044282	small molecule catabolic process	IEP	Enrichment
BP	GO:0046073	dTMP metabolic process	IEP	Enrichment
BP	GO:0046365	monosaccharide catabolic process	IEP	Enrichment
BP	GO:0046385	deoxyribose phosphate biosynthetic process	IEP	Enrichment
MF	GO:0052689	carboxylic ester hydrolase activity	IEP	Enrichment
BP	GO:0055067	monovalent inorganic cation homeostasis	IEP	Enrichment
BP	GO:0071840	cellular component organization or biogenesis	IEP	Enrichment
BP	GO:0072527	pyrimidine-containing compound metabolic process	IEP	Enrichment
BP	GO:0072528	pyrimidine-containing compound biosynthetic process	IEP	Enrichment
MF	GO:0097159	organic cyclic compound binding	IEP	Enrichment
MF	GO:0097367	carbohydrate derivative binding	IEP	Enrichment
CC	GO:0098533	ATPase dependent transmembrane transport complex	IEP	Enrichment
CC	GO:0098797	plasma membrane protein complex	IEP	Enrichment
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Enrichment
MF	GO:0140101	catalytic activity, acting on a tRNA	IEP	Enrichment
MF	GO:1901265	nucleoside phosphate binding	IEP	Enrichment
MF	GO:1901363	heterocyclic compound binding	IEP	Enrichment
CC	GO:1902495	transmembrane transporter complex	IEP	Enrichment
CC	GO:1904949	ATPase complex	IEP	Enrichment
CC	GO:1990351	transporter complex	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR020560	PRibGlycinamide_synth_C-dom	328	415
IPR020562	PRibGlycinamide_synth_N	8	104
IPR020561	PRibGlycinamid_synth_ATP-grasp	105	292

External Links

UniProtKB	D7FCC0

CBI65827 (purD, HPB8_270)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation