CBI67232 (leuS, HPB8_1675)

Aliases : leuS, HPB8_1675

Description : leucyl-tRNA synthetase [Ensembl]. Leucyl-tRNA synthetase, tRNA synthetases class I (I, tRNA synthetases class I (M) [Interproscan].

Gene families : OG_02_0000728 (OrthoFinder) Phylogenetic Tree(s): OG0000728_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: CBI67232
Cluster	HCCA: Cluster_16

Target	Alias	Description	ECC score	Gene Family Method
AAC73743	leuS, b0642	leucyl-tRNA synthetase [Ensembl]. Leucyl-tRNA...	0.05	OrthoFinder
AAK99039	spr0235, leuS	Leucyl-tRNA synthetase [Ensembl]. Leucyl-tRNA...	0.03	OrthoFinder
AAL19599	STM0648, leuS	leucine tRNA synthetase [Ensembl]. Leucyl-tRNA...	0.03	OrthoFinder
AGT25290	N559_3648	leucyl-tRNA synthetase [Ensembl]. Domain 2,...	0.04	OrthoFinder
AHY40297	leuS, CJ8421_05425	leucyl-tRNA ligase [Ensembl]. Leucyl-tRNA synthetase,...	0.09	OrthoFinder
AKI49656	leuS, L2625_01769	leucyl-tRNA synthetase [Ensembl]. Methionyl/Leucyl tRNA...	0.04	OrthoFinder
AKP15329	leuS, WX61_01280	Leucine--tRNA ligase [Ensembl]. Leucyl-tRNA synthetase,...	0.03	OrthoFinder
CCG26473	No alias	Leucyl-tRNA synthetase [Ensembl]. Leucyl-tRNA...	0.03	OrthoFinder
CRP36119	leuS	Leucine--tRNA ligase [Ensembl]. Leucyl-tRNA synthetase,...	0.07	OrthoFinder
EDJ91709	leuS, CGSHi22421_08138	leucyl-tRNA synthetase [Ensembl]. Leucyl-tRNA...	0.03	OrthoFinder
KNA56394	VCV51_032954	leucyl-tRNA synthetase [Ensembl]. Leucyl-tRNA...	0.05	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEA	Interproscan
MF	GO:0002161	aminoacyl-tRNA editing activity	IEA	Interproscan
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006399	tRNA metabolic process	None	Extended
BP	GO:0006418	tRNA aminoacylation for protein translation	IEA	Interproscan
BP	GO:0006520	cellular amino acid metabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016788	hydrolase activity, acting on ester bonds	None	Extended
MF	GO:0016874	ligase activity	None	Extended
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034660	ncRNA metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0043038	amino acid activation	None	Extended
BP	GO:0043039	tRNA aminoacylation	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
MF	GO:0052689	carboxylic ester hydrolase activity	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140098	catalytic activity, acting on RNA	None	Extended
MF	GO:0140101	catalytic activity, acting on a tRNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003916	DNA topoisomerase activity	IEP	Enrichment
MF	GO:0003918	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity	IEP	Enrichment
MF	GO:0004619	phosphoglycerate mutase activity	IEP	Enrichment
MF	GO:0004637	phosphoribosylamine-glycine ligase activity	IEP	Enrichment
MF	GO:0004655	porphobilinogen synthase activity	IEP	Enrichment
BP	GO:0006007	glucose catabolic process	IEP	Enrichment
BP	GO:0006144	purine nucleobase metabolic process	IEP	Enrichment
BP	GO:0006265	DNA topological change	IEP	Enrichment
BP	GO:0006270	DNA replication initiation	IEP	Enrichment
BP	GO:0006275	regulation of DNA replication	IEP	Enrichment
BP	GO:0006885	regulation of pH	IEP	Enrichment
BP	GO:0006996	organelle organization	IEP	Enrichment
MF	GO:0008094	ATPase, acting on DNA	IEP	Enrichment
MF	GO:0008134	transcription factor binding	IEP	Enrichment
BP	GO:0009112	nucleobase metabolic process	IEP	Enrichment
BP	GO:0009113	purine nucleobase biosynthetic process	IEP	Enrichment
BP	GO:0009889	regulation of biosynthetic process	IEP	Enrichment
BP	GO:0010556	regulation of macromolecule biosynthetic process	IEP	Enrichment
MF	GO:0015562	efflux transmembrane transporter activity	IEP	Enrichment
BP	GO:0016043	cellular component organization	IEP	Enrichment
MF	GO:0016853	isomerase activity	IEP	Enrichment
MF	GO:0016866	intramolecular transferase activity	IEP	Enrichment
MF	GO:0016868	intramolecular transferase activity, phosphotransferases	IEP	Enrichment
MF	GO:0016879	ligase activity, forming carbon-nitrogen bonds	IEP	Enrichment
BP	GO:0019222	regulation of metabolic process	IEP	Enrichment
BP	GO:0019320	hexose catabolic process	IEP	Enrichment
MF	GO:0030145	manganese ion binding	IEP	Enrichment
BP	GO:0031323	regulation of cellular metabolic process	IEP	Enrichment
BP	GO:0031326	regulation of cellular biosynthetic process	IEP	Enrichment
BP	GO:0042440	pigment metabolic process	IEP	Enrichment
BP	GO:0044282	small molecule catabolic process	IEP	Enrichment
BP	GO:0046112	nucleobase biosynthetic process	IEP	Enrichment
BP	GO:0046148	pigment biosynthetic process	IEP	Enrichment
BP	GO:0046365	monosaccharide catabolic process	IEP	Enrichment
BP	GO:0051276	chromosome organization	IEP	Enrichment
BP	GO:0055067	monovalent inorganic cation homeostasis	IEP	Enrichment
BP	GO:0060255	regulation of macromolecule metabolic process	IEP	Enrichment
BP	GO:0071103	DNA conformation change	IEP	Enrichment
BP	GO:0071840	cellular component organization or biogenesis	IEP	Enrichment
BP	GO:2000112	regulation of cellular macromolecule biosynthetic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR002300	aa-tRNA-synth_Ia	412	611
IPR015413	Methionyl/Leucyl_tRNA_Synth	32	178
IPR025709	Leu_tRNA-synth_edit	218	398

External Links

UniProtKB	D7FGC5

CBI67232 (leuS, HPB8_1675)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation