AKP14179 (mutM, WX61_00090)

Aliases : mutM, WX61_00090

Description : Formamidopyrimidine-DNA glycosylase [Ensembl]. Zinc finger found in FPG and IleRS, Formamidopyrimidine-DNA glycosylase H2TH domain, Formamidopyrimidine-DNA glycosylase N-terminal domain [Interproscan].

Gene families : OG_02_0000689 (OrthoFinder) Phylogenetic Tree(s): OG0000689_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AKP14179
Cluster	HCCA: Cluster_8

Target	Alias	Description	ECC score	Gene Family Method
CCG27151	No alias	Formamidopyrimidine-DNA glycosylase [Ensembl]. Zinc...	0.03	OrthoFinder
CPC86246	mutM, ERS093114_01512	Formamidopyrimidine-DNA glycosylase [Ensembl]. Zinc...	0.02	OrthoFinder
KNA52494	VCV51_030151	formamidopyrimidine-DNA glycosylase [Ensembl]. Zinc...	0.03	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	None	Extended
MF	GO:0003684	damaged DNA binding	IEA	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	None	Extended
BP	GO:0006284	base-excision repair	IEA	Interproscan
BP	GO:0006289	nucleotide-excision repair	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008270	zinc ion binding	IEA	Interproscan
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016798	hydrolase activity, acting on glycosyl bonds	None	Extended
MF	GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	IEA	Interproscan
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043169	cation binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
MF	GO:0046872	metal ion binding	None	Extended
MF	GO:0046914	transition metal ion binding	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEP	Enrichment
MF	GO:0003916	DNA topoisomerase activity	IEP	Enrichment
MF	GO:0003918	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity	IEP	Enrichment
MF	GO:0004089	carbonate dehydratase activity	IEP	Enrichment
MF	GO:0004150	dihydroneopterin aldolase activity	IEP	Enrichment
MF	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	IEP	Enrichment
BP	GO:0006098	pentose-phosphate shunt	IEP	Enrichment
BP	GO:0006265	DNA topological change	IEP	Enrichment
BP	GO:0006308	DNA catabolic process	IEP	Enrichment
BP	GO:0006364	rRNA processing	IEP	Enrichment
BP	GO:0006740	NADPH regeneration	IEP	Enrichment
BP	GO:0006996	organelle organization	IEP	Enrichment
MF	GO:0008312	7S RNA binding	IEP	Enrichment
MF	GO:0008483	transaminase activity	IEP	Enrichment
MF	GO:0008837	diaminopimelate epimerase activity	IEP	Enrichment
MF	GO:0008882	[glutamate-ammonia-ligase] adenylyltransferase activity	IEP	Enrichment
MF	GO:0008987	quinolinate synthetase A activity	IEP	Enrichment
CC	GO:0009318	exodeoxyribonuclease VII complex	IEP	Enrichment
BP	GO:0016043	cellular component organization	IEP	Enrichment
BP	GO:0016072	rRNA metabolic process	IEP	Enrichment
MF	GO:0016740	transferase activity	IEP	Enrichment
MF	GO:0016769	transferase activity, transferring nitrogenous groups	IEP	Enrichment
MF	GO:0016836	hydro-lyase activity	IEP	Enrichment
MF	GO:0017076	purine nucleotide binding	IEP	Enrichment
MF	GO:0019842	vitamin binding	IEP	Enrichment
MF	GO:0030170	pyridoxal phosphate binding	IEP	Enrichment
MF	GO:0032553	ribonucleotide binding	IEP	Enrichment
MF	GO:0032555	purine ribonucleotide binding	IEP	Enrichment
BP	GO:0034470	ncRNA processing	IEP	Enrichment
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Enrichment
MF	GO:0036094	small molecule binding	IEP	Enrichment
BP	GO:0042558	pteridine-containing compound metabolic process	IEP	Enrichment
BP	GO:0043165	Gram-negative-bacterium-type cell outer membrane assembly	IEP	Enrichment
MF	GO:0043168	anion binding	IEP	Enrichment
BP	GO:0044265	cellular macromolecule catabolic process	IEP	Enrichment
MF	GO:0047661	amino-acid racemase activity	IEP	Enrichment
CC	GO:0048500	signal recognition particle	IEP	Enrichment
MF	GO:0050661	NADP binding	IEP	Enrichment
BP	GO:0051276	chromosome organization	IEP	Enrichment
MF	GO:0052855	ADP-dependent NAD(P)H-hydrate dehydratase activity	IEP	Enrichment
MF	GO:0070279	vitamin B6 binding	IEP	Enrichment
BP	GO:0071103	DNA conformation change	IEP	Enrichment
BP	GO:0071709	membrane assembly	IEP	Enrichment
BP	GO:0071840	cellular component organization or biogenesis	IEP	Enrichment
MF	GO:0097367	carbohydrate derivative binding	IEP	Enrichment
MF	GO:1901265	nucleoside phosphate binding	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR012319	FPG_cat	1	119
IPR010663	Znf_FPG/IleRS	248	275
IPR015886	DNA_glyclase/AP_lyase_DNA-bd	135	225

External Links

No external refs found!

AKP14179 (mutM, WX61_00090)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation