AKP15329 (leuS, WX61_01280)

Aliases : leuS, WX61_01280

Description : Leucine--tRNA ligase [Ensembl]. Leucyl-tRNA synthetase, tRNA synthetases class I (I, tRNA synthetases class I (M), Anticodon-binding domain of tRNA [Interproscan].

Gene families : OG_02_0000728 (OrthoFinder) Phylogenetic Tree(s): OG0000728_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AKP15329
Cluster	HCCA: Cluster_12

Target	Alias	Description	ECC score	Gene Family Method
AAC73743	leuS, b0642	leucyl-tRNA synthetase [Ensembl]. Leucyl-tRNA...	0.06	OrthoFinder
AAK99039	spr0235, leuS	Leucyl-tRNA synthetase [Ensembl]. Leucyl-tRNA...	0.07	OrthoFinder
AAL19599	STM0648, leuS	leucine tRNA synthetase [Ensembl]. Leucyl-tRNA...	0.09	OrthoFinder
AGT25290	N559_3648	leucyl-tRNA synthetase [Ensembl]. Domain 2,...	0.05	OrthoFinder
AKI49656	leuS, L2625_01769	leucyl-tRNA synthetase [Ensembl]. Methionyl/Leucyl tRNA...	0.07	OrthoFinder
CBI67232	leuS, HPB8_1675	leucyl-tRNA synthetase [Ensembl]. Leucyl-tRNA...	0.03	OrthoFinder
CCG26473	No alias	Leucyl-tRNA synthetase [Ensembl]. Leucyl-tRNA...	0.06	OrthoFinder
CRP36119	leuS	Leucine--tRNA ligase [Ensembl]. Leucyl-tRNA synthetase,...	0.06	OrthoFinder
EDJ91709	leuS, CGSHi22421_08138	leucyl-tRNA synthetase [Ensembl]. Leucyl-tRNA...	0.05	OrthoFinder
KNA56394	VCV51_032954	leucyl-tRNA synthetase [Ensembl]. Leucyl-tRNA...	0.09	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEA	Interproscan
MF	GO:0002161	aminoacyl-tRNA editing activity	IEA	Interproscan
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006399	tRNA metabolic process	None	Extended
BP	GO:0006418	tRNA aminoacylation for protein translation	IEA	Interproscan
BP	GO:0006520	cellular amino acid metabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016788	hydrolase activity, acting on ester bonds	None	Extended
MF	GO:0016874	ligase activity	None	Extended
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034660	ncRNA metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0043038	amino acid activation	None	Extended
BP	GO:0043039	tRNA aminoacylation	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
MF	GO:0052689	carboxylic ester hydrolase activity	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140098	catalytic activity, acting on RNA	None	Extended
MF	GO:0140101	catalytic activity, acting on a tRNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000096	sulfur amino acid metabolic process	IEP	Enrichment
MF	GO:0003871	5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity	IEP	Enrichment
MF	GO:0003911	DNA ligase (NAD+) activity	IEP	Enrichment
MF	GO:0003922	GMP synthase (glutamine-hydrolyzing) activity	IEP	Enrichment
MF	GO:0003924	GTPase activity	IEP	Enrichment
MF	GO:0004176	ATP-dependent peptidase activity	IEP	Enrichment
MF	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	IEP	Enrichment
MF	GO:0004743	pyruvate kinase activity	IEP	Enrichment
MF	GO:0004820	glycine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004832	valine-tRNA ligase activity	IEP	Enrichment
CC	GO:0005737	cytoplasm	IEP	Enrichment
BP	GO:0006091	generation of precursor metabolites and energy	IEP	Enrichment
BP	GO:0006098	pentose-phosphate shunt	IEP	Enrichment
BP	GO:0006177	GMP biosynthetic process	IEP	Enrichment
BP	GO:0006426	glycyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006438	valyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006740	NADPH regeneration	IEP	Enrichment
MF	GO:0008703	5-amino-6-(5-phosphoribosylamino)uracil reductase activity	IEP	Enrichment
MF	GO:0008882	[glutamate-ammonia-ligase] adenylyltransferase activity	IEP	Enrichment
BP	GO:0009086	methionine biosynthetic process	IEP	Enrichment
BP	GO:0016310	phosphorylation	IEP	Enrichment
MF	GO:0017111	nucleoside-triphosphatase activity	IEP	Enrichment
BP	GO:0019725	cellular homeostasis	IEP	Enrichment
MF	GO:0030955	potassium ion binding	IEP	Enrichment
MF	GO:0031420	alkali metal ion binding	IEP	Enrichment
BP	GO:0031554	regulation of DNA-templated transcription, termination	IEP	Enrichment
MF	GO:0042085	5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity	IEP	Enrichment
BP	GO:0042592	homeostatic process	IEP	Enrichment
BP	GO:0043244	regulation of protein-containing complex disassembly	IEP	Enrichment
BP	GO:0045454	cell redox homeostasis	IEP	Enrichment
BP	GO:0046037	GMP metabolic process	IEP	Enrichment
MF	GO:0050661	NADP binding	IEP	Enrichment
BP	GO:0055114	obsolete oxidation-reduction process	IEP	Enrichment
BP	GO:0065008	regulation of biological quality	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR002300	aa-tRNA-synth_Ia	635	675
IPR002300	aa-tRNA-synth_Ia	432	588
IPR015413	Methionyl/Leucyl_tRNA_Synth	41	173
IPR025709	Leu_tRNA-synth_edit	223	417
IPR013155	M/V/L/I-tRNA-synth_anticd-bd	720	840

External Links

No external refs found!

AKP15329 (leuS, WX61_01280)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation