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  5. AAL21210

AAL21210 (STM2309, menD)


Aliases : STM2309, menD

Description : 2-oxoglutarate decarboxylase [Ensembl]. Thiamine pyrophosphate enzyme, Middle domain of thiamine pyrophosphate [Interproscan].


Gene families : OG_02_0001378 (OrthoFinder) Phylogenetic Tree(s): OG0001378_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: AAL21210
Cluster HCCA: Cluster_35

Target Alias Description ECC score Gene Family Method Actions
AAC75324 menD, b2264 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carbox... 0.12 OrthoFinder
AKI49671 menD, L2625_01786 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylic... 0.03 OrthoFinder
EDJ90806 CGSHi22421_05255 2-oxoglutarate decarboxylase [Ensembl]. Thiamine... 0.03 OrthoFinder

Type GO Term Name Evidence Source
MF GO:0003824 catalytic activity IEA Interproscan
MF GO:0030976 thiamine pyrophosphate binding IEA Interproscan
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Type GO Term Name Evidence Source
BP GO:0000041 transition metal ion transport IEP Enrichment
MF GO:0000166 nucleotide binding IEP Enrichment
BP GO:0001514 selenocysteine incorporation IEP Enrichment
MF GO:0004418 hydroxymethylbilane synthase activity IEP Enrichment
MF GO:0004618 phosphoglycerate kinase activity IEP Enrichment
MF GO:0004619 phosphoglycerate mutase activity IEP Enrichment
MF GO:0004743 pyruvate kinase activity IEP Enrichment
MF GO:0004817 cysteine-tRNA ligase activity IEP Enrichment
MF GO:0004852 uroporphyrinogen-III synthase activity IEP Enrichment
MF GO:0004853 uroporphyrinogen decarboxylase activity IEP Enrichment
BP GO:0005975 carbohydrate metabolic process IEP Enrichment
BP GO:0005996 monosaccharide metabolic process IEP Enrichment
BP GO:0006006 glucose metabolic process IEP Enrichment
BP GO:0006007 glucose catabolic process IEP Enrichment
BP GO:0006071 glycerol metabolic process IEP Enrichment
BP GO:0006082 organic acid metabolic process IEP Enrichment
BP GO:0006090 pyruvate metabolic process IEP Enrichment
BP GO:0006096 glycolytic process IEP Enrichment
BP GO:0006106 fumarate metabolic process IEP Enrichment
BP GO:0006165 nucleoside diphosphate phosphorylation IEP Enrichment
BP GO:0006417 regulation of translation IEP Enrichment
BP GO:0006423 cysteinyl-tRNA aminoacylation IEP Enrichment
BP GO:0006451 translational readthrough IEP Enrichment
BP GO:0006508 proteolysis IEP Enrichment
BP GO:0006612 protein targeting to membrane IEP Enrichment
BP GO:0006613 cotranslational protein targeting to membrane IEP Enrichment
BP GO:0006614 SRP-dependent cotranslational protein targeting to membrane IEP Enrichment
BP GO:0006757 ATP generation from ADP IEP Enrichment
BP GO:0006807 nitrogen compound metabolic process IEP Enrichment
BP GO:0006826 iron ion transport IEP Enrichment
MF GO:0008134 transcription factor binding IEP Enrichment
BP GO:0008152 metabolic process IEP Enrichment
MF GO:0008233 peptidase activity IEP Enrichment
MF GO:0008312 7S RNA binding IEP Enrichment
MF GO:0008998 ribonucleoside-triphosphate reductase activity IEP Enrichment
BP GO:0009056 catabolic process IEP Enrichment
BP GO:0009132 nucleoside diphosphate metabolic process IEP Enrichment
BP GO:0009135 purine nucleoside diphosphate metabolic process IEP Enrichment
BP GO:0009179 purine ribonucleoside diphosphate metabolic process IEP Enrichment
BP GO:0009185 ribonucleoside diphosphate metabolic process IEP Enrichment
BP GO:0010608 posttranscriptional regulation of gene expression IEP Enrichment
MF GO:0015232 heme transmembrane transporter activity IEP Enrichment
BP GO:0015886 heme transport IEP Enrichment
BP GO:0016052 carbohydrate catabolic process IEP Enrichment
MF GO:0016491 oxidoreductase activity IEP Enrichment
MF GO:0016787 hydrolase activity IEP Enrichment
BP GO:0017004 cytochrome complex assembly IEP Enrichment
MF GO:0017076 purine nucleotide binding IEP Enrichment
BP GO:0018130 heterocycle biosynthetic process IEP Enrichment
CC GO:0019008 molybdopterin synthase complex IEP Enrichment
MF GO:0019203 carbohydrate phosphatase activity IEP Enrichment
BP GO:0019318 hexose metabolic process IEP Enrichment
BP GO:0019320 hexose catabolic process IEP Enrichment
BP GO:0019400 alditol metabolic process IEP Enrichment
BP GO:0019438 aromatic compound biosynthetic process IEP Enrichment
BP GO:0019538 protein metabolic process IEP Enrichment
BP GO:0019752 carboxylic acid metabolic process IEP Enrichment
MF GO:0030145 manganese ion binding IEP Enrichment
MF GO:0030955 potassium ion binding IEP Enrichment
MF GO:0031420 alkali metal ion binding IEP Enrichment
BP GO:0032268 regulation of cellular protein metabolic process IEP Enrichment
MF GO:0032553 ribonucleotide binding IEP Enrichment
MF GO:0032555 purine ribonucleotide binding IEP Enrichment
BP GO:0033013 tetrapyrrole metabolic process IEP Enrichment
BP GO:0033014 tetrapyrrole biosynthetic process IEP Enrichment
BP GO:0033365 protein localization to organelle IEP Enrichment
BP GO:0034248 regulation of cellular amide metabolic process IEP Enrichment
BP GO:0034613 cellular protein localization IEP Enrichment
BP GO:0034622 cellular protein-containing complex assembly IEP Enrichment
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Enrichment
MF GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity IEP Enrichment
BP GO:0043436 oxoacid metabolic process IEP Enrichment
MF GO:0043546 molybdopterin cofactor binding IEP Enrichment
BP GO:0044249 cellular biosynthetic process IEP Enrichment
BP GO:0044281 small molecule metabolic process IEP Enrichment
BP GO:0045047 protein targeting to ER IEP Enrichment
BP GO:0046031 ADP metabolic process IEP Enrichment
BP GO:0046034 ATP metabolic process IEP Enrichment
BP GO:0046365 monosaccharide catabolic process IEP Enrichment
BP GO:0046483 heterocycle metabolic process IEP Enrichment
MF GO:0046872 metal ion binding IEP Enrichment
BP GO:0046939 nucleotide phosphorylation IEP Enrichment
MF GO:0048472 threonine-phosphate decarboxylase activity IEP Enrichment
CC GO:0048500 signal recognition particle IEP Enrichment
MF GO:0050308 sugar-phosphatase activity IEP Enrichment
BP GO:0051246 regulation of protein metabolic process IEP Enrichment
MF GO:0051536 iron-sulfur cluster binding IEP Enrichment
MF GO:0051540 metal cluster binding IEP Enrichment
BP GO:0051668 localization within membrane IEP Enrichment
BP GO:0055114 obsolete oxidation-reduction process IEP Enrichment
BP GO:0065003 protein-containing complex assembly IEP Enrichment
BP GO:0070727 cellular macromolecule localization IEP Enrichment
BP GO:0070972 protein localization to endoplasmic reticulum IEP Enrichment
BP GO:0071704 organic substance metabolic process IEP Enrichment
BP GO:0072594 establishment of protein localization to organelle IEP Enrichment
BP GO:0072599 establishment of protein localization to endoplasmic reticulum IEP Enrichment
BP GO:0072657 protein localization to membrane IEP Enrichment
BP GO:0090150 establishment of protein localization to membrane IEP Enrichment
MF GO:0097367 carbohydrate derivative binding IEP Enrichment
MF GO:0140096 catalytic activity, acting on a protein IEP Enrichment
MF GO:1901265 nucleoside phosphate binding IEP Enrichment
BP GO:1901360 organic cyclic compound metabolic process IEP Enrichment
BP GO:1901362 organic cyclic compound biosynthetic process IEP Enrichment
BP GO:1901564 organonitrogen compound metabolic process IEP Enrichment
BP GO:1901575 organic substance catabolic process IEP Enrichment
BP GO:1901576 organic substance biosynthetic process IEP Enrichment
BP GO:1901678 iron coordination entity transport IEP Enrichment
CC GO:1990904 ribonucleoprotein complex IEP Enrichment
InterPro domains Description Start Stop
IPR011766 TPP_enzyme-bd_C 415 534
IPR032264 MenD_middle 185 388
IPR012001 Thiamin_PyroP_enz_TPP-bd_dom 9 135
No external refs found!