CPD27156 (dnaE, ERS093114_02435)

Aliases : dnaE, ERS093114_02435

Description : DNA polymerase III alpha subunit [Ensembl]. PHP domain, Helix-hairpin-helix motif, OB-fold nucleic acid binding domain, Bacterial DNA polymerase III alpha NTPase domain, Bacterial DNA polymerase III alpha subunit finger domain [Interproscan].

Gene families : OG_02_0000325 (OrthoFinder) Phylogenetic Tree(s): OG0000325_tree

Sequence : coding (download), protein (download)

Download

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: CPD27156
Cluster	HCCA: Cluster_27

Target	Alias	Description	ECC score	Gene Family Method
AAK99599	spr0795, dnaE	DNA-polymerase III alpha-chain [Ensembl]. PHP domain,...	0.04	OrthoFinder
CCG26417	No alias	DNA polymerase III alpha subunit [Ensembl]. PHP domain,...	0.08	OrthoFinder
CCP46191	dnaE2, Rv3370c	Probable DNA polymerase III (alpha chain) DnaE2 (DNA...	0.02	OrthoFinder
CRO13404	dnaE	DNA polymerase III subunit alpha [Ensembl]. PHP domain,...	0.02	OrthoFinder
KNA51808	VCV51_031511	DNA polymerase III [Ensembl]. PHP domain,...	0.03	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	IEA	Interproscan
MF	GO:0003824	catalytic activity	IEA	Interproscan
MF	GO:0004518	nuclease activity	None	Extended
MF	GO:0004527	exonuclease activity	None	Extended
MF	GO:0005488	binding	None	Extended
BP	GO:0006260	DNA replication	IEA	Interproscan
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008408	3'-5' exonuclease activity	IEA	Interproscan
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009059	macromolecule biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016788	hydrolase activity, acting on ester bonds	None	Extended
BP	GO:0034645	cellular macromolecule biosynthetic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

Toggle parental

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEP	Enrichment
MF	GO:0003723	RNA binding	IEP	Enrichment
MF	GO:0003909	DNA ligase activity	IEP	Enrichment
MF	GO:0003911	DNA ligase (NAD+) activity	IEP	Enrichment
MF	GO:0004140	dephospho-CoA kinase activity	IEP	Enrichment
MF	GO:0004418	hydroxymethylbilane synthase activity	IEP	Enrichment
MF	GO:0004655	porphobilinogen synthase activity	IEP	Enrichment
MF	GO:0004813	alanine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004852	uroporphyrinogen-III synthase activity	IEP	Enrichment
MF	GO:0005524	ATP binding	IEP	Enrichment
MF	GO:0005525	GTP binding	IEP	Enrichment
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	Enrichment
BP	GO:0006281	DNA repair	IEP	Enrichment
BP	GO:0006419	alanyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006605	protein targeting	IEP	Enrichment
BP	GO:0006612	protein targeting to membrane	IEP	Enrichment
BP	GO:0006613	cotranslational protein targeting to membrane	IEP	Enrichment
BP	GO:0006614	SRP-dependent cotranslational protein targeting to membrane	IEP	Enrichment
BP	GO:0006725	cellular aromatic compound metabolic process	IEP	Enrichment
BP	GO:0006777	Mo-molybdopterin cofactor biosynthetic process	IEP	Enrichment
BP	GO:0006793	phosphorus metabolic process	IEP	Enrichment
BP	GO:0006796	phosphate-containing compound metabolic process	IEP	Enrichment
BP	GO:0006807	nitrogen compound metabolic process	IEP	Enrichment
BP	GO:0006886	intracellular protein transport	IEP	Enrichment
BP	GO:0006974	cellular response to DNA damage stimulus	IEP	Enrichment
BP	GO:0015936	coenzyme A metabolic process	IEP	Enrichment
BP	GO:0015937	coenzyme A biosynthetic process	IEP	Enrichment
BP	GO:0016070	RNA metabolic process	IEP	Enrichment
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	IEP	Enrichment
MF	GO:0016835	carbon-oxygen lyase activity	IEP	Enrichment
MF	GO:0016836	hydro-lyase activity	IEP	Enrichment
MF	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	IEP	Enrichment
MF	GO:0016886	ligase activity, forming phosphoric ester bonds	IEP	Enrichment
BP	GO:0017004	cytochrome complex assembly	IEP	Enrichment
MF	GO:0017076	purine nucleotide binding	IEP	Enrichment
BP	GO:0018130	heterocycle biosynthetic process	IEP	Enrichment
MF	GO:0019001	guanyl nucleotide binding	IEP	Enrichment
CC	GO:0019008	molybdopterin synthase complex	IEP	Enrichment
BP	GO:0019438	aromatic compound biosynthetic process	IEP	Enrichment
BP	GO:0019637	organophosphate metabolic process	IEP	Enrichment
BP	GO:0019720	Mo-molybdopterin cofactor metabolic process	IEP	Enrichment
MF	GO:0030554	adenyl nucleotide binding	IEP	Enrichment
MF	GO:0032553	ribonucleotide binding	IEP	Enrichment
MF	GO:0032555	purine ribonucleotide binding	IEP	Enrichment
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Enrichment
MF	GO:0032561	guanyl ribonucleotide binding	IEP	Enrichment
BP	GO:0033013	tetrapyrrole metabolic process	IEP	Enrichment
BP	GO:0033014	tetrapyrrole biosynthetic process	IEP	Enrichment
BP	GO:0033365	protein localization to organelle	IEP	Enrichment
BP	GO:0033554	cellular response to stress	IEP	Enrichment
BP	GO:0033866	nucleoside bisphosphate biosynthetic process	IEP	Enrichment
BP	GO:0034030	ribonucleoside bisphosphate biosynthetic process	IEP	Enrichment
BP	GO:0034033	purine nucleoside bisphosphate biosynthetic process	IEP	Enrichment
BP	GO:0034613	cellular protein localization	IEP	Enrichment
BP	GO:0034622	cellular protein-containing complex assembly	IEP	Enrichment
BP	GO:0034641	cellular nitrogen compound metabolic process	IEP	Enrichment
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Enrichment
MF	GO:0036094	small molecule binding	IEP	Enrichment
MF	GO:0043167	ion binding	IEP	Enrichment
MF	GO:0043168	anion binding	IEP	Enrichment
BP	GO:0043545	molybdopterin cofactor metabolic process	IEP	Enrichment
BP	GO:0044238	primary metabolic process	IEP	Enrichment
BP	GO:0045047	protein targeting to ER	IEP	Enrichment
BP	GO:0046483	heterocycle metabolic process	IEP	Enrichment
BP	GO:0046907	intracellular transport	IEP	Enrichment
BP	GO:0051189	prosthetic group metabolic process	IEP	Enrichment
BP	GO:0051641	cellular localization	IEP	Enrichment
BP	GO:0051649	establishment of localization in cell	IEP	Enrichment
BP	GO:0051668	localization within membrane	IEP	Enrichment
BP	GO:0051716	cellular response to stimulus	IEP	Enrichment
BP	GO:0070727	cellular macromolecule localization	IEP	Enrichment
BP	GO:0070972	protein localization to endoplasmic reticulum	IEP	Enrichment
BP	GO:0072594	establishment of protein localization to organelle	IEP	Enrichment
BP	GO:0072599	establishment of protein localization to endoplasmic reticulum	IEP	Enrichment
BP	GO:0072657	protein localization to membrane	IEP	Enrichment
BP	GO:0090150	establishment of protein localization to membrane	IEP	Enrichment
BP	GO:0090304	nucleic acid metabolic process	IEP	Enrichment
BP	GO:0090407	organophosphate biosynthetic process	IEP	Enrichment
MF	GO:0097367	carbohydrate derivative binding	IEP	Enrichment
MF	GO:1901265	nucleoside phosphate binding	IEP	Enrichment
BP	GO:1901360	organic cyclic compound metabolic process	IEP	Enrichment
BP	GO:1901362	organic cyclic compound biosynthetic process	IEP	Enrichment
BP	GO:1901564	organonitrogen compound metabolic process	IEP	Enrichment
BP	GO:1901566	organonitrogen compound biosynthetic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR004365	NA-bd_OB_tRNA	918	985
IPR011708	DNA_pol3_alpha_NTPase_dom	263	501
IPR040982	DNA_pol3_finger	504	667
IPR029460	DNAPol_HHH	740	828
IPR004013	PHP_dom	5	120

External Links

No external refs found!

CPD27156 (dnaE, ERS093114_02435)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation