AAK99047 (spr0243, proS)

Aliases : spr0243, proS

Description : Prolyl-tRNA synthetase [Ensembl]. Anticodon binding domain, Aminoacyl-tRNA editing domain, tRNA synthetase class II core domain (G [Interproscan].

Gene families : OG_02_0000443 (OrthoFinder) Phylogenetic Tree(s): OG0000443_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AAK99047
Cluster	HCCA: Cluster_16

Target	Alias	Description	ECC score	Gene Family Method
AKI49315	proS, L2625_01409	prolyl-tRNA synthetase [Ensembl]. Aminoacyl-tRNA...	0.04	OrthoFinder
AKP14223	proS, WX61_00134	Proline--tRNA ligase [Ensembl]. Anticodon binding...	0.03	OrthoFinder
CPC35118	proS, ERS093114_00161	Prolyl-tRNA synthetase [Ensembl]. Anticodon binding...	0.04	OrthoFinder
CRN72909	proS	Proline--tRNA ligase [Ensembl]. Anticodon binding...	0.02	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEA	Interproscan
MF	GO:0002161	aminoacyl-tRNA editing activity	IEA	Interproscan
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016788	hydrolase activity, acting on ester bonds	None	Extended
MF	GO:0016874	ligase activity	None	Extended
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0052689	carboxylic ester hydrolase activity	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140098	catalytic activity, acting on RNA	None	Extended
MF	GO:0140101	catalytic activity, acting on a tRNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000160	phosphorelay signal transduction system	IEP	Enrichment
MF	GO:0003676	nucleic acid binding	IEP	Enrichment
MF	GO:0003677	DNA binding	IEP	Enrichment
MF	GO:0004177	aminopeptidase activity	IEP	Enrichment
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	Enrichment
BP	GO:0006259	DNA metabolic process	IEP	Enrichment
BP	GO:0006260	DNA replication	IEP	Enrichment
BP	GO:0006281	DNA repair	IEP	Enrichment
BP	GO:0006725	cellular aromatic compound metabolic process	IEP	Enrichment
BP	GO:0006807	nitrogen compound metabolic process	IEP	Enrichment
BP	GO:0006950	response to stress	IEP	Enrichment
BP	GO:0006974	cellular response to DNA damage stimulus	IEP	Enrichment
MF	GO:0008080	N-acetyltransferase activity	IEP	Enrichment
MF	GO:0008144	drug binding	IEP	Enrichment
BP	GO:0008150	biological_process	IEP	Enrichment
BP	GO:0008152	metabolic process	IEP	Enrichment
MF	GO:0008238	exopeptidase activity	IEP	Enrichment
MF	GO:0008658	penicillin binding	IEP	Enrichment
MF	GO:0008963	phospho-N-acetylmuramoyl-pentapeptide-transferase activity	IEP	Enrichment
MF	GO:0009378	four-way junction helicase activity	IEP	Enrichment
BP	GO:0009403	toxin biosynthetic process	IEP	Enrichment
BP	GO:0009404	toxin metabolic process	IEP	Enrichment
MF	GO:0009982	pseudouridine synthase activity	IEP	Enrichment
BP	GO:0009987	cellular process	IEP	Enrichment
BP	GO:0016070	RNA metabolic process	IEP	Enrichment
BP	GO:0016311	dephosphorylation	IEP	Enrichment
MF	GO:0016407	acetyltransferase activity	IEP	Enrichment
MF	GO:0016410	N-acyltransferase activity	IEP	Enrichment
MF	GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	IEP	Enrichment
MF	GO:0016780	phosphotransferase activity, for other substituted phosphate groups	IEP	Enrichment
BP	GO:0019748	secondary metabolic process	IEP	Enrichment
MF	GO:0033218	amide binding	IEP	Enrichment
MF	GO:0033293	monocarboxylic acid binding	IEP	Enrichment
BP	GO:0033554	cellular response to stress	IEP	Enrichment
BP	GO:0034641	cellular nitrogen compound metabolic process	IEP	Enrichment
BP	GO:0035556	intracellular signal transduction	IEP	Enrichment
BP	GO:0043170	macromolecule metabolic process	IEP	Enrichment
BP	GO:0044237	cellular metabolic process	IEP	Enrichment
BP	GO:0044238	primary metabolic process	IEP	Enrichment
BP	GO:0044260	cellular macromolecule metabolic process	IEP	Enrichment
BP	GO:0044550	secondary metabolite biosynthetic process	IEP	Enrichment
BP	GO:0046483	heterocycle metabolic process	IEP	Enrichment
BP	GO:0050896	response to stimulus	IEP	Enrichment
BP	GO:0051716	cellular response to stimulus	IEP	Enrichment
BP	GO:0071704	organic substance metabolic process	IEP	Enrichment
BP	GO:0090304	nucleic acid metabolic process	IEP	Enrichment
MF	GO:0140097	catalytic activity, acting on DNA	IEP	Enrichment
BP	GO:1901360	organic cyclic compound metabolic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR004154	Anticodon-bd	522	611
IPR007214	YbaK/aa-tRNA-synth-assoc-dom	295	414
IPR002314	aa-tRNA-synt_IIb	94	493

External Links

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AAK99047 (spr0243, proS)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation