AAK99055 (spr0251, polC)

Aliases : spr0251, polC

Description : DNA polymerase III, alpha subunit [Ensembl]. PHP domain, Exonuclease, DNA polymerase III polC-type N-terminus II, Bacterial DNA polymerase III alpha NTPase domain, Bacterial DNA polymerase III alpha subunit finger domain [Interproscan].

Gene families : OG_02_0001788 (OrthoFinder) Phylogenetic Tree(s): OG0001788_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AAK99055
Cluster	HCCA: Cluster_3

Target	Alias	Description	ECC score	Gene Family Method	Actions
AEA94498	polC, OG1RF_11811	DNA polymerase III PolC [Ensembl]. PHP domain,...	0.04	OrthoFinder
CCG27342	No alias	DNA polymerase III polC-type [Ensembl]....	0.08	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	IEA	Interproscan
MF	GO:0004518	nuclease activity	None	Extended
MF	GO:0004527	exonuclease activity	None	Extended
BP	GO:0006260	DNA replication	IEA	Interproscan
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008408	3'-5' exonuclease activity	IEA	Interproscan
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009059	macromolecule biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016788	hydrolase activity, acting on ester bonds	None	Extended
BP	GO:0034645	cellular macromolecule biosynthetic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000155	phosphorelay sensor kinase activity	IEP	Enrichment
BP	GO:0000160	phosphorelay signal transduction system	IEP	Enrichment
MF	GO:0002161	aminoacyl-tRNA editing activity	IEP	Enrichment
MF	GO:0003677	DNA binding	IEP	Enrichment
MF	GO:0003848	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity	IEP	Enrichment
MF	GO:0004150	dihydroneopterin aldolase activity	IEP	Enrichment
MF	GO:0004177	aminopeptidase activity	IEP	Enrichment
MF	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	IEP	Enrichment
MF	GO:0004618	phosphoglycerate kinase activity	IEP	Enrichment
MF	GO:0004672	protein kinase activity	IEP	Enrichment
MF	GO:0004673	protein histidine kinase activity	IEP	Enrichment
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEP	Enrichment
MF	GO:0004817	cysteine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004832	valine-tRNA ligase activity	IEP	Enrichment
MF	GO:0005488	binding	IEP	Enrichment
CC	GO:0005737	cytoplasm	IEP	Enrichment
BP	GO:0006082	organic acid metabolic process	IEP	Enrichment
BP	GO:0006098	pentose-phosphate shunt	IEP	Enrichment
BP	GO:0006259	DNA metabolic process	IEP	Enrichment
BP	GO:0006281	DNA repair	IEP	Enrichment
BP	GO:0006418	tRNA aminoacylation for protein translation	IEP	Enrichment
BP	GO:0006725	cellular aromatic compound metabolic process	IEP	Enrichment
BP	GO:0006739	NADP metabolic process	IEP	Enrichment
BP	GO:0006740	NADPH regeneration	IEP	Enrichment
BP	GO:0006950	response to stress	IEP	Enrichment
BP	GO:0006974	cellular response to DNA damage stimulus	IEP	Enrichment
BP	GO:0007165	signal transduction	IEP	Enrichment
MF	GO:0008233	peptidase activity	IEP	Enrichment
MF	GO:0008998	ribonucleoside-triphosphate reductase activity	IEP	Enrichment
BP	GO:0015074	DNA integration	IEP	Enrichment
MF	GO:0016301	kinase activity	IEP	Enrichment
MF	GO:0016740	transferase activity	IEP	Enrichment
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	IEP	Enrichment
MF	GO:0016774	phosphotransferase activity, carboxyl group as acceptor	IEP	Enrichment
MF	GO:0016775	phosphotransferase activity, nitrogenous group as acceptor	IEP	Enrichment
MF	GO:0016832	aldehyde-lyase activity	IEP	Enrichment
MF	GO:0016874	ligase activity	IEP	Enrichment
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	IEP	Enrichment
BP	GO:0019752	carboxylic acid metabolic process	IEP	Enrichment
MF	GO:0031072	heat shock protein binding	IEP	Enrichment
BP	GO:0033554	cellular response to stress	IEP	Enrichment
BP	GO:0035556	intracellular signal transduction	IEP	Enrichment
BP	GO:0043436	oxoacid metabolic process	IEP	Enrichment
BP	GO:0046483	heterocycle metabolic process	IEP	Enrichment
BP	GO:0050789	regulation of biological process	IEP	Enrichment
BP	GO:0050794	regulation of cellular process	IEP	Enrichment
BP	GO:0050896	response to stimulus	IEP	Enrichment
BP	GO:0051156	glucose 6-phosphate metabolic process	IEP	Enrichment
BP	GO:0051716	cellular response to stimulus	IEP	Enrichment
MF	GO:0052689	carboxylic ester hydrolase activity	IEP	Enrichment
BP	GO:0065007	biological regulation	IEP	Enrichment
BP	GO:0090304	nucleic acid metabolic process	IEP	Enrichment
MF	GO:0097159	organic cyclic compound binding	IEP	Enrichment
MF	GO:0140096	catalytic activity, acting on a protein	IEP	Enrichment
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Enrichment
MF	GO:0140101	catalytic activity, acting on a tRNA	IEP	Enrichment
MF	GO:0140299	small molecule sensor activity	IEP	Enrichment
BP	GO:1901360	organic cyclic compound metabolic process	IEP	Enrichment
MF	GO:1901363	heterocyclic compound binding	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR028112	DNA_PolC-type_N_I	5	73
IPR004013	PHP_dom	340	699
IPR013520	Exonuclease_RNaseT/DNA_pol3	426	580
IPR011708	DNA_pol3_alpha_NTPase_dom	840	1021
IPR011708	DNA_pol3_alpha_NTPase_dom	1036	1108
IPR024754	DNA_PolC-like_N_II	92	206
IPR040982	DNA_pol3_finger	1112	1267

External Links

No external refs found!

AAK99055 (spr0251, polC)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation