CRO27413 (spoT_1)


Aliases : spoT_1

Description : Bifunctional (p)ppGpp synthase/hydrolase SpoT [Ensembl]. HD domain, ACT domain, TGS domain, Region found in RelA / SpoT proteins [Interproscan].


Gene families : OG_02_0000300 (OrthoFinder) Phylogenetic Tree(s): OG0000300_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: CRO27413
Cluster HCCA: Cluster_22

Target Alias Description ECC score Gene Family Method Actions
AKP14370 spoT, WX61_00286 Bifunctional (p)ppGpp synthase/hydrolase SpoT [Ensembl].... 0.03 OrthoFinder
AKP14447 relA, WX61_00365 GTP pyrophosphokinase [Ensembl]. HD domain, TGS domain,... 0.02 OrthoFinder
CBI66541 spoT, HPB8_984 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase... 0.04 OrthoFinder
CCG26981 No alias GTP pyrophosphokinase, (p)ppGpp synthetase I [Ensembl].... 0.03 OrthoFinder

Type GO Term Name Evidence Source
BP GO:0015969 guanosine tetraphosphate metabolic process IEA Interproscan
Type GO Term Name Evidence Source
MF GO:0003674 molecular_function IEP Enrichment
MF GO:0003735 structural constituent of ribosome IEP Enrichment
MF GO:0003824 catalytic activity IEP Enrichment
MF GO:0003883 CTP synthase activity IEP Enrichment
MF GO:0003899 DNA-directed 5'-3' RNA polymerase activity IEP Enrichment
MF GO:0003905 alkylbase DNA N-glycosylase activity IEP Enrichment
MF GO:0003954 NADH dehydrogenase activity IEP Enrichment
MF GO:0003955 NAD(P)H dehydrogenase (quinone) activity IEP Enrichment
MF GO:0004018 N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity IEP Enrichment
MF GO:0004150 dihydroneopterin aldolase activity IEP Enrichment
MF GO:0004424 imidazoleglycerol-phosphate dehydratase activity IEP Enrichment
MF GO:0004609 phosphatidylserine decarboxylase activity IEP Enrichment
MF GO:0004618 phosphoglycerate kinase activity IEP Enrichment
MF GO:0004812 aminoacyl-tRNA ligase activity IEP Enrichment
MF GO:0004820 glycine-tRNA ligase activity IEP Enrichment
MF GO:0005198 structural molecule activity IEP Enrichment
CC GO:0005840 ribosome IEP Enrichment
BP GO:0006082 organic acid metabolic process IEP Enrichment
BP GO:0006188 IMP biosynthetic process IEP Enrichment
BP GO:0006220 pyrimidine nucleotide metabolic process IEP Enrichment
BP GO:0006221 pyrimidine nucleotide biosynthetic process IEP Enrichment
BP GO:0006260 DNA replication IEP Enrichment
BP GO:0006351 transcription, DNA-templated IEP Enrichment
BP GO:0006399 tRNA metabolic process IEP Enrichment
BP GO:0006412 translation IEP Enrichment
BP GO:0006418 tRNA aminoacylation for protein translation IEP Enrichment
BP GO:0006426 glycyl-tRNA aminoacylation IEP Enrichment
BP GO:0006518 peptide metabolic process IEP Enrichment
BP GO:0006520 cellular amino acid metabolic process IEP Enrichment
BP GO:0006629 lipid metabolic process IEP Enrichment
BP GO:0006643 membrane lipid metabolic process IEP Enrichment
BP GO:0006644 phospholipid metabolic process IEP Enrichment
BP GO:0006664 glycolipid metabolic process IEP Enrichment
BP GO:0006720 isoprenoid metabolic process IEP Enrichment
BP GO:0006721 terpenoid metabolic process IEP Enrichment
MF GO:0008097 5S rRNA binding IEP Enrichment
MF GO:0008137 NADH dehydrogenase (ubiquinone) activity IEP Enrichment
BP GO:0008299 isoprenoid biosynthetic process IEP Enrichment
MF GO:0008408 3'-5' exonuclease activity IEP Enrichment
BP GO:0008610 lipid biosynthetic process IEP Enrichment
BP GO:0008654 phospholipid biosynthetic process IEP Enrichment
MF GO:0008661 1-deoxy-D-xylulose-5-phosphate synthase activity IEP Enrichment
MF GO:0008725 DNA-3-methyladenine glycosylase activity IEP Enrichment
MF GO:0008759 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity IEP Enrichment
MF GO:0008883 glutamyl-tRNA reductase activity IEP Enrichment
BP GO:0009058 biosynthetic process IEP Enrichment
BP GO:0009059 macromolecule biosynthetic process IEP Enrichment
BP GO:0009123 nucleoside monophosphate metabolic process IEP Enrichment
BP GO:0009124 nucleoside monophosphate biosynthetic process IEP Enrichment
BP GO:0009126 purine nucleoside monophosphate metabolic process IEP Enrichment
BP GO:0009127 purine nucleoside monophosphate biosynthetic process IEP Enrichment
BP GO:0009156 ribonucleoside monophosphate biosynthetic process IEP Enrichment
BP GO:0009161 ribonucleoside monophosphate metabolic process IEP Enrichment
BP GO:0009165 nucleotide biosynthetic process IEP Enrichment
BP GO:0009167 purine ribonucleoside monophosphate metabolic process IEP Enrichment
BP GO:0009168 purine ribonucleoside monophosphate biosynthetic process IEP Enrichment
BP GO:0009245 lipid A biosynthetic process IEP Enrichment
BP GO:0009247 glycolipid biosynthetic process IEP Enrichment
BP GO:0009312 oligosaccharide biosynthetic process IEP Enrichment
BP GO:0016070 RNA metabolic process IEP Enrichment
BP GO:0016114 terpenoid biosynthetic process IEP Enrichment
MF GO:0016491 oxidoreductase activity IEP Enrichment
MF GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEP Enrichment
MF GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor IEP Enrichment
MF GO:0016744 transketolase or transaldolase activity IEP Enrichment
MF GO:0016774 phosphotransferase activity, carboxyl group as acceptor IEP Enrichment
MF GO:0016779 nucleotidyltransferase activity IEP Enrichment
MF GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds IEP Enrichment
MF GO:0016829 lyase activity IEP Enrichment
MF GO:0016830 carbon-carbon lyase activity IEP Enrichment
MF GO:0016842 amidine-lyase activity IEP Enrichment
MF GO:0016855 racemase and epimerase activity, acting on amino acids and derivatives IEP Enrichment
MF GO:0016874 ligase activity IEP Enrichment
MF GO:0016875 ligase activity, forming carbon-oxygen bonds IEP Enrichment
MF GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors IEP Enrichment
BP GO:0018130 heterocycle biosynthetic process IEP Enrichment
MF GO:0019104 DNA N-glycosylase activity IEP Enrichment
MF GO:0019213 deacetylase activity IEP Enrichment
BP GO:0019438 aromatic compound biosynthetic process IEP Enrichment
BP GO:0019538 protein metabolic process IEP Enrichment
BP GO:0019752 carboxylic acid metabolic process IEP Enrichment
BP GO:0032784 regulation of DNA-templated transcription, elongation IEP Enrichment
MF GO:0034062 5'-3' RNA polymerase activity IEP Enrichment
BP GO:0034645 cellular macromolecule biosynthetic process IEP Enrichment
BP GO:0034654 nucleobase-containing compound biosynthetic process IEP Enrichment
BP GO:0034660 ncRNA metabolic process IEP Enrichment
MF GO:0036361 racemase activity, acting on amino acids and derivatives IEP Enrichment
BP GO:0043038 amino acid activation IEP Enrichment
BP GO:0043039 tRNA aminoacylation IEP Enrichment
BP GO:0043043 peptide biosynthetic process IEP Enrichment
BP GO:0043170 macromolecule metabolic process IEP Enrichment
CC GO:0043226 organelle IEP Enrichment
CC GO:0043228 non-membrane-bounded organelle IEP Enrichment
CC GO:0043229 intracellular organelle IEP Enrichment
CC GO:0043232 intracellular non-membrane-bounded organelle IEP Enrichment
BP GO:0043436 oxoacid metabolic process IEP Enrichment
BP GO:0043603 cellular amide metabolic process IEP Enrichment
BP GO:0043604 amide biosynthetic process IEP Enrichment
MF GO:0043733 DNA-3-methylbase glycosylase activity IEP Enrichment
BP GO:0044249 cellular biosynthetic process IEP Enrichment
BP GO:0044255 cellular lipid metabolic process IEP Enrichment
BP GO:0044260 cellular macromolecule metabolic process IEP Enrichment
BP GO:0044267 cellular protein metabolic process IEP Enrichment
BP GO:0044271 cellular nitrogen compound biosynthetic process IEP Enrichment
BP GO:0046040 IMP metabolic process IEP Enrichment
MF GO:0046429 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity IEP Enrichment
BP GO:0046467 membrane lipid biosynthetic process IEP Enrichment
BP GO:0046493 lipid A metabolic process IEP Enrichment
MF GO:0048038 quinone binding IEP Enrichment
MF GO:0050136 NADH dehydrogenase (quinone) activity IEP Enrichment
MF GO:0051287 NAD binding IEP Enrichment
MF GO:0052592 oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor IEP Enrichment
BP GO:0055114 obsolete oxidation-reduction process IEP Enrichment
MF GO:0070567 cytidylyltransferase activity IEP Enrichment
BP GO:0072527 pyrimidine-containing compound metabolic process IEP Enrichment
BP GO:0072528 pyrimidine-containing compound biosynthetic process IEP Enrichment
BP GO:0090407 organophosphate biosynthetic process IEP Enrichment
BP GO:0097659 nucleic acid-templated transcription IEP Enrichment
MF GO:0097747 RNA polymerase activity IEP Enrichment
MF GO:0140098 catalytic activity, acting on RNA IEP Enrichment
MF GO:0140101 catalytic activity, acting on a tRNA IEP Enrichment
BP GO:1901137 carbohydrate derivative biosynthetic process IEP Enrichment
BP GO:1901269 lipooligosaccharide metabolic process IEP Enrichment
BP GO:1901271 lipooligosaccharide biosynthetic process IEP Enrichment
BP GO:1901293 nucleoside phosphate biosynthetic process IEP Enrichment
BP GO:1901362 organic cyclic compound biosynthetic process IEP Enrichment
BP GO:1901566 organonitrogen compound biosynthetic process IEP Enrichment
BP GO:1901576 organic substance biosynthetic process IEP Enrichment
InterPro domains Description Start Stop
IPR007685 RelA_SpoT 177 287
IPR004095 TGS 330 389
IPR002912 ACT_dom 564 640