Coexpression cluster: Cluster_22 (HCCA)

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Average Expression Profile

Enriched GO Terms (corrected p-value < 0.05) (download table)
ID Label % in cluster Enrichment log2 p-value Corrected p-value
GO:0003735 structural constituent of ribosome 14.35% (30/209) 4.38 0.0 0.0
GO:0006412 translation 13.88% (29/209) 4.36 0.0 0.0
GO:0005198 structural molecule activity 14.35% (30/209) 4.25 0.0 0.0
GO:0043043 peptide biosynthetic process 13.88% (29/209) 4.3 0.0 0.0
GO:0006518 peptide metabolic process 13.88% (29/209) 4.3 0.0 0.0
GO:0043229 intracellular organelle 13.88% (29/209) 4.26 0.0 0.0
GO:0005840 ribosome 13.4% (28/209) 4.34 0.0 0.0
GO:0043604 amide biosynthetic process 13.88% (29/209) 4.2 0.0 0.0
GO:0043232 intracellular non-membrane-bounded organelle 13.4% (28/209) 4.25 0.0 0.0
GO:0043226 organelle 13.88% (29/209) 4.15 0.0 0.0
GO:0034645 cellular macromolecule biosynthetic process 15.79% (33/209) 3.82 0.0 0.0
GO:0043603 cellular amide metabolic process 13.88% (29/209) 4.09 0.0 0.0
GO:0043228 non-membrane-bounded organelle 13.4% (28/209) 4.13 0.0 0.0
GO:0044267 cellular protein metabolic process 14.35% (30/209) 3.91 0.0 0.0
GO:0044249 cellular biosynthetic process 23.44% (49/209) 2.75 0.0 0.0
GO:0044271 cellular nitrogen compound biosynthetic process 18.66% (39/209) 3.19 0.0 0.0
GO:1901576 organic substance biosynthetic process 23.44% (49/209) 2.72 0.0 0.0
GO:1901566 organonitrogen compound biosynthetic process 19.14% (40/209) 3.11 0.0 0.0
GO:0009059 macromolecule biosynthetic process 15.79% (33/209) 3.45 0.0 0.0
GO:0009058 biosynthetic process 24.88% (52/209) 2.42 0.0 0.0
GO:1901564 organonitrogen compound metabolic process 23.44% (49/209) 2.34 0.0 0.0
GO:0019538 protein metabolic process 14.83% (31/209) 3.06 0.0 0.0
GO:0044238 primary metabolic process 29.19% (61/209) 1.9 0.0 0.0
GO:0044237 cellular metabolic process 29.67% (62/209) 1.87 0.0 0.0
GO:0034641 cellular nitrogen compound metabolic process 22.97% (48/209) 2.22 0.0 0.0
GO:0044260 cellular macromolecule metabolic process 17.22% (36/209) 2.62 0.0 0.0
GO:0006807 nitrogen compound metabolic process 27.27% (57/209) 1.87 0.0 0.0
GO:0071704 organic substance metabolic process 30.14% (63/209) 1.69 0.0 0.0
GO:0008152 metabolic process 33.49% (70/209) 1.54 0.0 0.0
GO:0043170 macromolecule metabolic process 19.62% (41/209) 1.94 0.0 0.0
GO:0009987 cellular process 35.41% (74/209) 1.02 0.0 0.0
GO:1902600 proton transmembrane transport 3.35% (7/209) 4.6 0.0 0.0
GO:0019693 ribose phosphate metabolic process 3.83% (8/209) 3.87 0.0 0.0
GO:0009259 ribonucleotide metabolic process 3.83% (8/209) 3.87 0.0 0.0
GO:0009150 purine ribonucleotide metabolic process 3.83% (8/209) 3.87 0.0 0.0
GO:0098655 cation transmembrane transport 3.35% (7/209) 4.18 0.0 0.0
GO:0098662 inorganic cation transmembrane transport 3.35% (7/209) 4.18 0.0 0.0
GO:0098660 inorganic ion transmembrane transport 3.35% (7/209) 4.18 0.0 0.0
GO:0046034 ATP metabolic process 3.35% (7/209) 4.18 0.0 0.0
GO:0015986 ATP synthesis coupled proton transport 2.39% (5/209) 4.96 0.0 0.0
GO:0015985 energy coupled proton transport, down electrochemical gradient 2.39% (5/209) 4.96 0.0 0.0
GO:0009206 purine ribonucleoside triphosphate biosynthetic process 2.39% (5/209) 4.96 0.0 0.0
GO:0009205 purine ribonucleoside triphosphate metabolic process 2.39% (5/209) 4.96 0.0 0.0
GO:0009201 ribonucleoside triphosphate biosynthetic process 2.39% (5/209) 4.96 0.0 0.0
GO:0009199 ribonucleoside triphosphate metabolic process 2.39% (5/209) 4.96 0.0 0.0
GO:0009145 purine nucleoside triphosphate biosynthetic process 2.39% (5/209) 4.96 0.0 0.0
GO:0009142 nucleoside triphosphate biosynthetic process 2.39% (5/209) 4.96 0.0 0.0
GO:0006754 ATP biosynthetic process 2.39% (5/209) 4.96 0.0 0.0
GO:0009144 purine nucleoside triphosphate metabolic process 2.39% (5/209) 4.96 0.0 0.0
GO:0006163 purine nucleotide metabolic process 3.83% (8/209) 3.71 0.0 0.0
GO:0019637 organophosphate metabolic process 5.74% (12/209) 2.85 0.0 0.0
GO:0006796 phosphate-containing compound metabolic process 6.22% (13/209) 2.68 0.0 1e-06
GO:0072521 purine-containing compound metabolic process 3.83% (8/209) 3.64 0.0 1e-06
GO:0009117 nucleotide metabolic process 4.31% (9/209) 3.32 0.0 1e-06
GO:0006793 phosphorus metabolic process 6.22% (13/209) 2.6 0.0 1e-06
GO:0090407 organophosphate biosynthetic process 4.78% (10/209) 3.07 0.0 1e-06
GO:0006753 nucleoside phosphate metabolic process 4.31% (9/209) 3.27 0.0 1e-06
GO:0009152 purine ribonucleotide biosynthetic process 2.87% (6/209) 4.22 0.0 1e-06
GO:0009260 ribonucleotide biosynthetic process 2.87% (6/209) 4.22 0.0 1e-06
GO:0046390 ribose phosphate biosynthetic process 2.87% (6/209) 4.22 0.0 1e-06
GO:0009141 nucleoside triphosphate metabolic process 2.39% (5/209) 4.7 0.0 1e-06
GO:0034220 ion transmembrane transport 3.35% (7/209) 3.77 0.0 2e-06
GO:0006164 purine nucleotide biosynthetic process 2.87% (6/209) 3.96 1e-06 5e-06
GO:0055086 nucleobase-containing small molecule metabolic process 4.78% (10/209) 2.79 1e-06 7e-06
GO:0072522 purine-containing compound biosynthetic process 2.87% (6/209) 3.85 1e-06 9e-06
GO:1901135 carbohydrate derivative metabolic process 5.26% (11/209) 2.59 1e-06 9e-06
GO:0005575 cellular_component 22.01% (46/209) 1.01 2e-06 1.2e-05
GO:1901137 carbohydrate derivative biosynthetic process 3.35% (7/209) 3.38 3e-06 1.5e-05
GO:1901293 nucleoside phosphate biosynthetic process 3.35% (7/209) 3.38 3e-06 1.5e-05
GO:0009165 nucleotide biosynthetic process 3.35% (7/209) 3.38 3e-06 1.5e-05
GO:0034654 nucleobase-containing compound biosynthetic process 4.78% (10/209) 2.67 3e-06 1.5e-05
GO:0008150 biological_process 41.15% (86/209) 0.61 5e-06 2.7e-05
GO:0019843 rRNA binding 1.91% (4/209) 4.64 5e-06 2.9e-05
GO:0110165 cellular anatomical entity 20.1% (42/209) 0.97 1.3e-05 7.5e-05
GO:0003674 molecular_function 51.2% (107/209) 0.47 1.5e-05 8.3e-05
GO:0003723 RNA binding 4.78% (10/209) 2.31 2.7e-05 0.000151
GO:0006351 transcription, DNA-templated 1.44% (3/209) 4.96 3.3e-05 0.000177
GO:0097659 nucleic acid-templated transcription 1.44% (3/209) 4.96 3.3e-05 0.000177
GO:0044281 small molecule metabolic process 8.13% (17/209) 1.52 8.3e-05 0.000443
GO:0034062 5'-3' RNA polymerase activity 1.44% (3/209) 4.55 0.000127 0.000658
GO:0097747 RNA polymerase activity 1.44% (3/209) 4.55 0.000127 0.000658
GO:0003899 DNA-directed 5'-3' RNA polymerase activity 1.44% (3/209) 4.55 0.000127 0.000658
GO:0006139 nucleobase-containing compound metabolic process 9.09% (19/209) 1.36 0.000141 0.00072
GO:0019438 aromatic compound biosynthetic process 4.78% (10/209) 1.98 0.000195 0.000982
GO:0018130 heterocycle biosynthetic process 4.78% (10/209) 1.86 0.000393 0.001961
GO:0046483 heterocycle metabolic process 9.57% (20/209) 1.16 0.000586 0.00289
GO:1901362 organic cyclic compound biosynthetic process 4.78% (10/209) 1.78 0.000621 0.003025
GO:0006812 cation transport 3.83% (8/209) 2.03 0.000671 0.003232
GO:0006725 cellular aromatic compound metabolic process 9.57% (20/209) 1.14 0.000702 0.003346
GO:0009055 electron transfer activity 3.83% (8/209) 2.01 0.000749 0.00353
GO:1901360 organic cyclic compound metabolic process 9.57% (20/209) 1.12 0.000838 0.003905
GO:0000105 histidine biosynthetic process 1.44% (3/209) 3.74 0.001037 0.004532
GO:0006547 histidine metabolic process 1.44% (3/209) 3.74 0.001037 0.004532
GO:0015252 proton channel activity 0.96% (2/209) 4.96 0.001025 0.004576
GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain 0.96% (2/209) 4.96 0.001025 0.004576
GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 0.96% (2/209) 4.96 0.001025 0.004576
GO:0005261 cation channel activity 0.96% (2/209) 4.96 0.001025 0.004576
GO:0051540 metal cluster binding 3.35% (7/209) 2.1 0.001105 0.004734
GO:0051536 iron-sulfur cluster binding 3.35% (7/209) 2.1 0.001105 0.004734
GO:0008610 lipid biosynthetic process 2.39% (5/209) 2.43 0.002055 0.008712
GO:0003905 alkylbase DNA N-glycosylase activity 0.96% (2/209) 4.38 0.003011 0.012393
GO:0019104 DNA N-glycosylase activity 0.96% (2/209) 4.38 0.003011 0.012393
GO:0005216 ion channel activity 0.96% (2/209) 4.38 0.003011 0.012393
GO:0003824 catalytic activity 27.75% (58/209) 0.46 0.004584 0.018512
GO:0006811 ion transport 3.83% (8/209) 1.6 0.00457 0.018632
GO:0098796 membrane protein complex 1.91% (4/209) 2.5 0.004786 0.019144
GO:0044255 cellular lipid metabolic process 2.39% (5/209) 2.11 0.005439 0.021552
GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 1.44% (3/209) 2.96 0.005786 0.0221
GO:0008654 phospholipid biosynthetic process 1.44% (3/209) 2.96 0.005786 0.0221
GO:0006644 phospholipid metabolic process 1.44% (3/209) 2.96 0.005786 0.0221
GO:0015078 proton transmembrane transporter activity 1.91% (4/209) 2.44 0.00565 0.022183
GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 0.96% (2/209) 3.96 0.005894 0.022313
GO:0140098 catalytic activity, acting on RNA 2.87% (6/209) 1.79 0.007273 0.027291
GO:0008299 isoprenoid biosynthetic process 0.96% (2/209) 3.64 0.009616 0.035455
GO:0006720 isoprenoid metabolic process 0.96% (2/209) 3.64 0.009616 0.035455
GO:0016779 nucleotidyltransferase activity 1.91% (4/209) 2.21 0.010134 0.03704
GO:0006520 cellular amino acid metabolic process 3.35% (7/209) 1.5 0.011395 0.041294
GO:0008652 cellular amino acid biosynthetic process 1.91% (4/209) 2.15 0.011532 0.041435
GO:0051287 NAD binding 1.91% (4/209) 2.1 0.013048 0.046489
GO:0016491 oxidoreductase activity 10.05% (21/209) 0.74 0.013537 0.04783
Enriched Clades (corrected p-value < 0.05) (download table)
Clade % in cluster Enrichment log2 p-value Corrected p-value Gene Family Method
No enriched Clades found
Similar Clusters (download table)
Species Clustering Method Target Jaccard index Gene Family Method (for comparison) Actions
Campylobacter jejuni HCCA Cluster_2 0.075 OrthoFinder Compare
Campylobacter jejuni HCCA Cluster_8 0.109 OrthoFinder Compare
Campylobacter jejuni HCCA Cluster_11 0.029 OrthoFinder Compare
Campylobacter jejuni HCCA Cluster_12 0.04 OrthoFinder Compare
Clostridioides difficile HCCA Cluster_2 0.091 OrthoFinder Compare
Clostridioides difficile HCCA Cluster_31 0.031 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_5 0.032 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_7 0.05 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_12 0.057 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_18 0.045 OrthoFinder Compare
Escherichia coli HCCA Cluster_1 0.162 OrthoFinder Compare
Escherichia coli HCCA Cluster_2 0.039 OrthoFinder Compare
Escherichia coli HCCA Cluster_6 0.067 OrthoFinder Compare
Escherichia coli HCCA Cluster_38 0.027 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_3 0.057 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_7 0.031 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_8 0.029 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_11 0.031 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_14 0.03 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_17 0.099 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_23 0.028 OrthoFinder Compare
Helicobacter pylori HCCA Cluster_2 0.028 OrthoFinder Compare
Helicobacter pylori HCCA Cluster_6 0.027 OrthoFinder Compare
Helicobacter pylori HCCA Cluster_9 0.115 OrthoFinder Compare
Helicobacter pylori HCCA Cluster_10 0.027 OrthoFinder Compare
Helicobacter pylori HCCA Cluster_14 0.027 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_12 0.108 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_29 0.044 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_34 0.03 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_37 0.027 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_38 0.036 OrthoFinder Compare
Listeria monocytogenes HCCA Cluster_2 0.089 OrthoFinder Compare
Listeria monocytogenes HCCA Cluster_10 0.035 OrthoFinder Compare
Listeria monocytogenes HCCA Cluster_18 0.04 OrthoFinder Compare
Mycoplasma pneumoniae HCAA Cluster_3 0.045 OrthoFinder Compare
Mycoplasma pneumoniae HCAA Cluster_5 0.073 OrthoFinder Compare
Mycobacterium tuberculosis HCCA Cluster_1 0.043 OrthoFinder Compare
Mycobacterium tuberculosis HCCA Cluster_25 0.081 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_5 0.049 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_6 0.085 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_7 0.031 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_12 0.034 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_14 0.031 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_16 0.034 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_17 0.035 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_19 0.041 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_20 0.027 OrthoFinder Compare
Salmonella enterica HCCA Cluster_6 0.08 OrthoFinder Compare
Salmonella enterica HCCA Cluster_23 0.16 OrthoFinder Compare
Salmonella enterica HCCA Cluster_31 0.039 OrthoFinder Compare
Staphylococcus aureus HCCA Cluster_1 0.029 OrthoFinder Compare
Staphylococcus aureus HCCA Cluster_4 0.029 OrthoFinder Compare
Staphylococcus aureus HCCA Cluster_12 0.041 OrthoFinder Compare
Staphylococcus aureus HCCA Cluster_19 0.043 OrthoFinder Compare
Staphylococcus aureus HCCA Cluster_24 0.124 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_7 0.075 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_13 0.067 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_14 0.028 OrthoFinder Compare
Streptococcus pyogenes HCAA Cluster_4 0.095 OrthoFinder Compare
Streptococcus pyogenes HCAA Cluster_11 0.035 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_1 0.035 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_5 0.042 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_8 0.121 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_9 0.039 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_16 0.058 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_24 0.061 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_25 0.03 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_31 0.038 OrthoFinder Compare
Sequences (209) (download table)

InterPro Domains

GO Terms

Family Terms