CRO43647 (metZ)

Aliases : metZ

Description : O-succinylhomoserine sulfhydrylase [Ensembl]. Cys/Met metabolism PLP-dependent enzyme [Interproscan].

Gene families : OG_02_0000095 (OrthoFinder) Phylogenetic Tree(s): OG0000095_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: CRO43647
Cluster	HCCA: Cluster_22

Target	Alias	Description	ECC score	Gene Family Method	Actions
AKP14726	metZ, WX61_00648	O-succinylhomoserine sulfhydrylase [Ensembl]. Cys/Met...	0.04	OrthoFinder
EDJ91184	CGSHi22421_01659	cystathionine beta-lyase [Ensembl]. Cys/Met metabolism...	0.03	OrthoFinder

Type	GO Term	Name	Evidence	Source
BP	GO:0000096	sulfur amino acid metabolic process	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005488	binding	None	Extended
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006520	cellular amino acid metabolic process	None	Extended
BP	GO:0006534	cysteine metabolic process	None	Extended
BP	GO:0006790	sulfur compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009069	serine family amino acid metabolic process	None	Extended
BP	GO:0009092	homoserine metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0019346	transsulfuration	IEA	Interproscan
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
MF	GO:0019842	vitamin binding	None	Extended
MF	GO:0030170	pyridoxal phosphate binding	IEA	Interproscan
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0050667	homocysteine metabolic process	None	Extended
MF	GO:0070279	vitamin B6 binding	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901605	alpha-amino acid metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000049	tRNA binding	IEP	Enrichment
BP	GO:0000105	histidine biosynthetic process	IEP	Enrichment
MF	GO:0000166	nucleotide binding	IEP	Enrichment
MF	GO:0003678	DNA helicase activity	IEP	Enrichment
MF	GO:0003824	catalytic activity	IEP	Enrichment
MF	GO:0003879	ATP phosphoribosyltransferase activity	IEP	Enrichment
MF	GO:0003883	CTP synthase activity	IEP	Enrichment
MF	GO:0003905	alkylbase DNA N-glycosylase activity	IEP	Enrichment
MF	GO:0004019	adenylosuccinate synthase activity	IEP	Enrichment
MF	GO:0004150	dihydroneopterin aldolase activity	IEP	Enrichment
MF	GO:0004399	histidinol dehydrogenase activity	IEP	Enrichment
MF	GO:0004609	phosphatidylserine decarboxylase activity	IEP	Enrichment
MF	GO:0004618	phosphoglycerate kinase activity	IEP	Enrichment
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEP	Enrichment
MF	GO:0004826	phenylalanine-tRNA ligase activity	IEP	Enrichment
BP	GO:0006090	pyruvate metabolic process	IEP	Enrichment
BP	GO:0006096	glycolytic process	IEP	Enrichment
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	Enrichment
BP	GO:0006163	purine nucleotide metabolic process	IEP	Enrichment
BP	GO:0006165	nucleoside diphosphate phosphorylation	IEP	Enrichment
BP	GO:0006220	pyrimidine nucleotide metabolic process	IEP	Enrichment
BP	GO:0006221	pyrimidine nucleotide biosynthetic process	IEP	Enrichment
BP	GO:0006281	DNA repair	IEP	Enrichment
BP	GO:0006399	tRNA metabolic process	IEP	Enrichment
BP	GO:0006418	tRNA aminoacylation for protein translation	IEP	Enrichment
BP	GO:0006432	phenylalanyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006547	histidine metabolic process	IEP	Enrichment
BP	GO:0006553	lysine metabolic process	IEP	Enrichment
BP	GO:0006720	isoprenoid metabolic process	IEP	Enrichment
BP	GO:0006721	terpenoid metabolic process	IEP	Enrichment
BP	GO:0006725	cellular aromatic compound metabolic process	IEP	Enrichment
BP	GO:0006753	nucleoside phosphate metabolic process	IEP	Enrichment
BP	GO:0006757	ATP generation from ADP	IEP	Enrichment
BP	GO:0006760	folic acid-containing compound metabolic process	IEP	Enrichment
BP	GO:0006778	porphyrin-containing compound metabolic process	IEP	Enrichment
BP	GO:0006779	porphyrin-containing compound biosynthetic process	IEP	Enrichment
BP	GO:0006793	phosphorus metabolic process	IEP	Enrichment
BP	GO:0006796	phosphate-containing compound metabolic process	IEP	Enrichment
BP	GO:0006950	response to stress	IEP	Enrichment
BP	GO:0006974	cellular response to DNA damage stimulus	IEP	Enrichment
BP	GO:0008299	isoprenoid biosynthetic process	IEP	Enrichment
BP	GO:0008610	lipid biosynthetic process	IEP	Enrichment
MF	GO:0008641	ubiquitin-like modifier activating enzyme activity	IEP	Enrichment
BP	GO:0008652	cellular amino acid biosynthetic process	IEP	Enrichment
MF	GO:0008725	DNA-3-methyladenine glycosylase activity	IEP	Enrichment
MF	GO:0008837	diaminopimelate epimerase activity	IEP	Enrichment
BP	GO:0009058	biosynthetic process	IEP	Enrichment
BP	GO:0009085	lysine biosynthetic process	IEP	Enrichment
BP	GO:0009089	lysine biosynthetic process via diaminopimelate	IEP	Enrichment
BP	GO:0009117	nucleotide metabolic process	IEP	Enrichment
BP	GO:0009132	nucleoside diphosphate metabolic process	IEP	Enrichment
BP	GO:0009135	purine nucleoside diphosphate metabolic process	IEP	Enrichment
BP	GO:0009165	nucleotide biosynthetic process	IEP	Enrichment
BP	GO:0009179	purine ribonucleoside diphosphate metabolic process	IEP	Enrichment
BP	GO:0009185	ribonucleoside diphosphate metabolic process	IEP	Enrichment
BP	GO:0016052	carbohydrate catabolic process	IEP	Enrichment
BP	GO:0016053	organic acid biosynthetic process	IEP	Enrichment
BP	GO:0016114	terpenoid biosynthetic process	IEP	Enrichment
MF	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	IEP	Enrichment
MF	GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	IEP	Enrichment
MF	GO:0016757	glycosyltransferase activity	IEP	Enrichment
MF	GO:0016774	phosphotransferase activity, carboxyl group as acceptor	IEP	Enrichment
MF	GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	IEP	Enrichment
MF	GO:0016830	carbon-carbon lyase activity	IEP	Enrichment
MF	GO:0016832	aldehyde-lyase activity	IEP	Enrichment
MF	GO:0016854	racemase and epimerase activity	IEP	Enrichment
MF	GO:0016855	racemase and epimerase activity, acting on amino acids and derivatives	IEP	Enrichment
MF	GO:0016874	ligase activity	IEP	Enrichment
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	IEP	Enrichment
MF	GO:0016877	ligase activity, forming carbon-sulfur bonds	IEP	Enrichment
MF	GO:0016879	ligase activity, forming carbon-nitrogen bonds	IEP	Enrichment
MF	GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	IEP	Enrichment
BP	GO:0018130	heterocycle biosynthetic process	IEP	Enrichment
MF	GO:0019104	DNA N-glycosylase activity	IEP	Enrichment
BP	GO:0019438	aromatic compound biosynthetic process	IEP	Enrichment
BP	GO:0019637	organophosphate metabolic process	IEP	Enrichment
BP	GO:0033013	tetrapyrrole metabolic process	IEP	Enrichment
BP	GO:0033014	tetrapyrrole biosynthetic process	IEP	Enrichment
BP	GO:0033554	cellular response to stress	IEP	Enrichment
BP	GO:0034641	cellular nitrogen compound metabolic process	IEP	Enrichment
MF	GO:0036361	racemase activity, acting on amino acids and derivatives	IEP	Enrichment
BP	GO:0043038	amino acid activation	IEP	Enrichment
BP	GO:0043039	tRNA aminoacylation	IEP	Enrichment
MF	GO:0043138	3'-5' DNA helicase activity	IEP	Enrichment
MF	GO:0043733	DNA-3-methylbase glycosylase activity	IEP	Enrichment
MF	GO:0043752	adenosylcobinamide kinase activity	IEP	Enrichment
BP	GO:0044249	cellular biosynthetic process	IEP	Enrichment
BP	GO:0044255	cellular lipid metabolic process	IEP	Enrichment
BP	GO:0044271	cellular nitrogen compound biosynthetic process	IEP	Enrichment
BP	GO:0044283	small molecule biosynthetic process	IEP	Enrichment
BP	GO:0046031	ADP metabolic process	IEP	Enrichment
BP	GO:0046394	carboxylic acid biosynthetic process	IEP	Enrichment
MF	GO:0046429	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity	IEP	Enrichment
BP	GO:0046451	diaminopimelate metabolic process	IEP	Enrichment
BP	GO:0046483	heterocycle metabolic process	IEP	Enrichment
BP	GO:0046939	nucleotide phosphorylation	IEP	Enrichment
MF	GO:0047661	amino-acid racemase activity	IEP	Enrichment
BP	GO:0050896	response to stimulus	IEP	Enrichment
BP	GO:0051259	protein complex oligomerization	IEP	Enrichment
MF	GO:0051287	NAD binding	IEP	Enrichment
BP	GO:0051716	cellular response to stimulus	IEP	Enrichment
MF	GO:0052592	oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor	IEP	Enrichment
BP	GO:0055086	nucleobase-containing small molecule metabolic process	IEP	Enrichment
BP	GO:0055114	obsolete oxidation-reduction process	IEP	Enrichment
BP	GO:0070206	protein trimerization	IEP	Enrichment
MF	GO:0070402	NADPH binding	IEP	Enrichment
BP	GO:0072521	purine-containing compound metabolic process	IEP	Enrichment
BP	GO:0072527	pyrimidine-containing compound metabolic process	IEP	Enrichment
BP	GO:0072528	pyrimidine-containing compound biosynthetic process	IEP	Enrichment
BP	GO:0090407	organophosphate biosynthetic process	IEP	Enrichment
MF	GO:0140101	catalytic activity, acting on a tRNA	IEP	Enrichment
MF	GO:1901265	nucleoside phosphate binding	IEP	Enrichment
BP	GO:1901293	nucleoside phosphate biosynthetic process	IEP	Enrichment
BP	GO:1901360	organic cyclic compound metabolic process	IEP	Enrichment
BP	GO:1901362	organic cyclic compound biosynthetic process	IEP	Enrichment
BP	GO:1901566	organonitrogen compound biosynthetic process	IEP	Enrichment
BP	GO:1901576	organic substance biosynthetic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR000277	Cys/Met-Metab_PyrdxlP-dep_enz	20	400

External Links

Locus_tag	PAERUG_E11_London_26_VIM_2_06_13_02417

CRO43647 (metZ)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation