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CRO57149 (hemE)


Aliases : hemE

Description : Uroporphyrinogen decarboxylase [Ensembl]. Uroporphyrinogen decarboxylase (URO-D) [Interproscan].


Gene families : OG_02_0000933 (OrthoFinder) Phylogenetic Tree(s): OG0000933_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: CRO57149
Cluster HCCA: Cluster_61

Target Alias Description ECC score Gene Family Method Actions
AKP15737 hemE, WX61_01702 Uroporphyrinogen decarboxylase [Ensembl].... 0.03 OrthoFinder
CCP45476 hemE, Rv2678c Probable uroporphyrinogen decarboxylase HemE... 0.02 OrthoFinder

Type GO Term Name Evidence Source
MF GO:0004853 uroporphyrinogen decarboxylase activity IEA Interproscan
BP GO:0006779 porphyrin-containing compound biosynthetic process IEA Interproscan
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Type GO Term Name Evidence Source
MF GO:0000166 nucleotide binding IEP Enrichment
BP GO:0001522 pseudouridine synthesis IEP Enrichment
MF GO:0003676 nucleic acid binding IEP Enrichment
MF GO:0003690 double-stranded DNA binding IEP Enrichment
MF GO:0003723 RNA binding IEP Enrichment
MF GO:0003924 GTPase activity IEP Enrichment
MF GO:0004386 helicase activity IEP Enrichment
MF GO:0004486 methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity IEP Enrichment
MF GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity IEP Enrichment
MF GO:0005315 inorganic phosphate transmembrane transporter activity IEP Enrichment
MF GO:0005488 binding IEP Enrichment
MF GO:0005524 ATP binding IEP Enrichment
BP GO:0006139 nucleobase-containing compound metabolic process IEP Enrichment
BP GO:0006298 mismatch repair IEP Enrichment
BP GO:0006817 phosphate ion transport IEP Enrichment
MF GO:0008094 ATPase, acting on DNA IEP Enrichment
CC GO:0009295 nucleoid IEP Enrichment
BP GO:0009451 RNA modification IEP Enrichment
BP GO:0009890 negative regulation of biosynthetic process IEP Enrichment
BP GO:0009892 negative regulation of metabolic process IEP Enrichment
MF GO:0009982 pseudouridine synthase activity IEP Enrichment
BP GO:0010558 negative regulation of macromolecule biosynthetic process IEP Enrichment
BP GO:0010605 negative regulation of macromolecule metabolic process IEP Enrichment
MF GO:0016462 pyrophosphatase activity IEP Enrichment
MF GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors IEP Enrichment
MF GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor IEP Enrichment
MF GO:0016787 hydrolase activity IEP Enrichment
MF GO:0016817 hydrolase activity, acting on acid anhydrides IEP Enrichment
MF GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides IEP Enrichment
MF GO:0016853 isomerase activity IEP Enrichment
MF GO:0016866 intramolecular transferase activity IEP Enrichment
MF GO:0017076 purine nucleotide binding IEP Enrichment
MF GO:0017111 nucleoside-triphosphatase activity IEP Enrichment
MF GO:0030554 adenyl nucleotide binding IEP Enrichment
MF GO:0030983 mismatched DNA binding IEP Enrichment
BP GO:0031324 negative regulation of cellular metabolic process IEP Enrichment
BP GO:0031327 negative regulation of cellular biosynthetic process IEP Enrichment
MF GO:0032553 ribonucleotide binding IEP Enrichment
MF GO:0032555 purine ribonucleotide binding IEP Enrichment
MF GO:0032559 adenyl ribonucleotide binding IEP Enrichment
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Enrichment
MF GO:0036094 small molecule binding IEP Enrichment
MF GO:0043167 ion binding IEP Enrichment
MF GO:0043168 anion binding IEP Enrichment
BP GO:0043412 macromolecule modification IEP Enrichment
BP GO:0045892 negative regulation of transcription, DNA-templated IEP Enrichment
BP GO:0045934 negative regulation of nucleobase-containing compound metabolic process IEP Enrichment
MF GO:0047429 nucleoside-triphosphate diphosphatase activity IEP Enrichment
BP GO:0048519 negative regulation of biological process IEP Enrichment
BP GO:0048523 negative regulation of cellular process IEP Enrichment
BP GO:0051172 negative regulation of nitrogen compound metabolic process IEP Enrichment
BP GO:0051253 negative regulation of RNA metabolic process IEP Enrichment
BP GO:0090304 nucleic acid metabolic process IEP Enrichment
MF GO:0097159 organic cyclic compound binding IEP Enrichment
MF GO:0097367 carbohydrate derivative binding IEP Enrichment
MF GO:1901265 nucleoside phosphate binding IEP Enrichment
MF GO:1901363 heterocyclic compound binding IEP Enrichment
BP GO:1902679 negative regulation of RNA biosynthetic process IEP Enrichment
BP GO:1903507 negative regulation of nucleic acid-templated transcription IEP Enrichment
BP GO:2000113 negative regulation of cellular macromolecule biosynthetic process IEP Enrichment
InterPro domains Description Start Stop
IPR000257 Uroporphyrinogen_deCOase 5 348
Locus_tag PAERUG_E11_London_26_VIM_2_06_13_02831