AAC75622 (lepA, b2569)

Aliases : lepA, b2569

Description : back-translocating elongation factor EF4, GTPase [Ensembl]. Elongation factor Tu domain 2, Elongation factor G C-terminus, GTP-binding protein LepA C-terminus, Elongation factor Tu GTP binding domain [Interproscan].

Gene families : OG_02_0000878 (OrthoFinder) Phylogenetic Tree(s): OG0000878_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AAC75622
Cluster	HCCA: Cluster_40

Target	Alias	Description	ECC score	Gene Family Method
AAK99885	spr1082, lepA	GTP-binding protein LepA [Ensembl]. Elongation factor Tu...	0.06	OrthoFinder
ADK86706	lepA, MPNE_0314	GTP-binding protein LepA [Ensembl]. Elongation factor Tu...	0.04	OrthoFinder
AEA94477	lepA, OG1RF_11790	GTP-binding protein LepA [Ensembl]. Elongation factor Tu...	0.03	OrthoFinder
AGT23121	N559_1359, LepA	GTP-binding protein LepA [Ensembl]. Elongation factor Tu...	0.24	OrthoFinder
AKI49476	lepA, L2625_01578	membrane GTPase [Ensembl]. Translation elongation factor...	0.08	OrthoFinder
CBI66773	lepA, HPB8_1216	GTP-binding protein LepA [Ensembl]. Elongation factor Tu...	0.06	OrthoFinder
CPC82585	lepA, ERS093114_01414	Translation elongation factor LepA [Ensembl]. Elongation...	0.1	OrthoFinder
EDJ91269	CGSHi22421_02084	GTP-binding protein LepA [Ensembl]. Elongation factor Tu...	0.06	OrthoFinder
KNA51131	VCV51_031659, LepA	GTP-binding protein LepA [Ensembl]. Elongation factor Tu...	0.08	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003924	GTPase activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
MF	GO:0005525	GTP binding	IEA	Interproscan
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
MF	GO:0019001	guanyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032561	guanyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0001522	pseudouridine synthesis	IEP	Enrichment
MF	GO:0002161	aminoacyl-tRNA editing activity	IEP	Enrichment
MF	GO:0003676	nucleic acid binding	IEP	Enrichment
MF	GO:0003723	RNA binding	IEP	Enrichment
MF	GO:0003916	DNA topoisomerase activity	IEP	Enrichment
MF	GO:0003918	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity	IEP	Enrichment
MF	GO:0004107	chorismate synthase activity	IEP	Enrichment
MF	GO:0004312	fatty acid synthase activity	IEP	Enrichment
MF	GO:0004315	3-oxoacyl-[acyl-carrier-protein] synthase activity	IEP	Enrichment
MF	GO:0004518	nuclease activity	IEP	Enrichment
MF	GO:0004520	endodeoxyribonuclease activity	IEP	Enrichment
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEP	Enrichment
MF	GO:0004813	alanine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004814	arginine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004817	cysteine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004820	glycine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004832	valine-tRNA ligase activity	IEP	Enrichment
MF	GO:0005524	ATP binding	IEP	Enrichment
MF	GO:0005539	glycosaminoglycan binding	IEP	Enrichment
CC	GO:0005737	cytoplasm	IEP	Enrichment
BP	GO:0006082	organic acid metabolic process	IEP	Enrichment
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	Enrichment
BP	GO:0006260	DNA replication	IEP	Enrichment
BP	GO:0006265	DNA topological change	IEP	Enrichment
BP	GO:0006364	rRNA processing	IEP	Enrichment
BP	GO:0006399	tRNA metabolic process	IEP	Enrichment
BP	GO:0006418	tRNA aminoacylation for protein translation	IEP	Enrichment
BP	GO:0006419	alanyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006420	arginyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006423	cysteinyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006426	glycyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006438	valyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006520	cellular amino acid metabolic process	IEP	Enrichment
BP	GO:0006629	lipid metabolic process	IEP	Enrichment
BP	GO:0006644	phospholipid metabolic process	IEP	Enrichment
BP	GO:0006725	cellular aromatic compound metabolic process	IEP	Enrichment
BP	GO:0006807	nitrogen compound metabolic process	IEP	Enrichment
BP	GO:0006996	organelle organization	IEP	Enrichment
MF	GO:0008094	ATPase, acting on DNA	IEP	Enrichment
BP	GO:0008152	metabolic process	IEP	Enrichment
BP	GO:0008360	regulation of cell shape	IEP	Enrichment
BP	GO:0008610	lipid biosynthetic process	IEP	Enrichment
BP	GO:0008654	phospholipid biosynthetic process	IEP	Enrichment
MF	GO:0008685	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity	IEP	Enrichment
MF	GO:0008915	lipid-A-disaccharide synthase activity	IEP	Enrichment
BP	GO:0009058	biosynthetic process	IEP	Enrichment
BP	GO:0009143	nucleoside triphosphate catabolic process	IEP	Enrichment
BP	GO:0009240	isopentenyl diphosphate biosynthetic process	IEP	Enrichment
BP	GO:0009254	peptidoglycan turnover	IEP	Enrichment
BP	GO:0009451	RNA modification	IEP	Enrichment
MF	GO:0009982	pseudouridine synthase activity	IEP	Enrichment
BP	GO:0009987	cellular process	IEP	Enrichment
BP	GO:0016053	organic acid biosynthetic process	IEP	Enrichment
BP	GO:0016070	RNA metabolic process	IEP	Enrichment
BP	GO:0016072	rRNA metabolic process	IEP	Enrichment
MF	GO:0016726	oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor	IEP	Enrichment
MF	GO:0016788	hydrolase activity, acting on ester bonds	IEP	Enrichment
MF	GO:0016838	carbon-oxygen lyase activity, acting on phosphates	IEP	Enrichment
MF	GO:0016849	phosphorus-oxygen lyase activity	IEP	Enrichment
MF	GO:0016853	isomerase activity	IEP	Enrichment
MF	GO:0016866	intramolecular transferase activity	IEP	Enrichment
MF	GO:0016874	ligase activity	IEP	Enrichment
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	IEP	Enrichment
MF	GO:0016887	ATPase	IEP	Enrichment
BP	GO:0019288	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway	IEP	Enrichment
BP	GO:0019682	glyceraldehyde-3-phosphate metabolic process	IEP	Enrichment
BP	GO:0019752	carboxylic acid metabolic process	IEP	Enrichment
BP	GO:0022603	regulation of anatomical structure morphogenesis	IEP	Enrichment
BP	GO:0022604	regulation of cell morphogenesis	IEP	Enrichment
MF	GO:0030554	adenyl nucleotide binding	IEP	Enrichment
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Enrichment
MF	GO:0032977	membrane insertase activity	IEP	Enrichment
BP	GO:0034641	cellular nitrogen compound metabolic process	IEP	Enrichment
BP	GO:0034645	cellular macromolecule biosynthetic process	IEP	Enrichment
BP	GO:0034660	ncRNA metabolic process	IEP	Enrichment
MF	GO:0035596	methylthiotransferase activity	IEP	Enrichment
MF	GO:0042834	peptidoglycan binding	IEP	Enrichment
BP	GO:0043038	amino acid activation	IEP	Enrichment
BP	GO:0043039	tRNA aminoacylation	IEP	Enrichment
BP	GO:0043170	macromolecule metabolic process	IEP	Enrichment
BP	GO:0043412	macromolecule modification	IEP	Enrichment
BP	GO:0043436	oxoacid metabolic process	IEP	Enrichment
BP	GO:0044237	cellular metabolic process	IEP	Enrichment
BP	GO:0044238	primary metabolic process	IEP	Enrichment
BP	GO:0044249	cellular biosynthetic process	IEP	Enrichment
BP	GO:0044255	cellular lipid metabolic process	IEP	Enrichment
BP	GO:0044260	cellular macromolecule metabolic process	IEP	Enrichment
BP	GO:0044281	small molecule metabolic process	IEP	Enrichment
BP	GO:0044283	small molecule biosynthetic process	IEP	Enrichment
BP	GO:0046483	heterocycle metabolic process	IEP	Enrichment
BP	GO:0046490	isopentenyl diphosphate metabolic process	IEP	Enrichment
MF	GO:0050497	alkylthioltransferase activity	IEP	Enrichment
BP	GO:0050793	regulation of developmental process	IEP	Enrichment
BP	GO:0050992	dimethylallyl diphosphate biosynthetic process	IEP	Enrichment
BP	GO:0050993	dimethylallyl diphosphate metabolic process	IEP	Enrichment
BP	GO:0051276	chromosome organization	IEP	Enrichment
MF	GO:0051745	4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity	IEP	Enrichment
MF	GO:0052689	carboxylic ester hydrolase activity	IEP	Enrichment
MF	GO:0070567	cytidylyltransferase activity	IEP	Enrichment
BP	GO:0071103	DNA conformation change	IEP	Enrichment
BP	GO:0071704	organic substance metabolic process	IEP	Enrichment
BP	GO:0090304	nucleic acid metabolic process	IEP	Enrichment
MF	GO:0140097	catalytic activity, acting on DNA	IEP	Enrichment
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Enrichment
MF	GO:0140101	catalytic activity, acting on a tRNA	IEP	Enrichment
MF	GO:0140104	molecular carrier activity	IEP	Enrichment
MF	GO:0140597	protein carrier activity	IEP	Enrichment
BP	GO:1901135	carbohydrate derivative metabolic process	IEP	Enrichment
BP	GO:1901360	organic cyclic compound metabolic process	IEP	Enrichment
BP	GO:1901564	organonitrogen compound metabolic process	IEP	Enrichment
BP	GO:1901576	organic substance biosynthetic process	IEP	Enrichment
BP	GO:1903509	liposaccharide metabolic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR000640	EFG_V-like	399	482
IPR013842	LepA_CTD	487	592
IPR000795	T_Tr_GTP-bd_dom	2	181
IPR004161	EFTu-like_2	205	275

External Links

UniProtKB	P60785

AAC75622 (lepA, b2569)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation